vs
Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and SANDRIDGE ENERGY INC (SD). Click either name above to swap in a different company.
SANDRIDGE ENERGY INC is the larger business by last-quarter revenue ($39.4M vs $20.0M, roughly 2.0× AGIOS PHARMACEUTICALS, INC.). SANDRIDGE ENERGY INC runs the higher net margin — 54.9% vs -541.1%, a 596.0% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs 1.1%). SANDRIDGE ENERGY INC produced more free cash flow last quarter ($14.4M vs $-97.3M). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs 14.1%).
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
SandRidge Energy, Inc. is a company engaged in hydrocarbon exploration in the Mid-Continent region of the United States. It is organized in Delaware and headquartered in Oklahoma City, Oklahoma.
AGIO vs SD — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $20.0M | $39.4M |
| Net Profit | $-108.0M | $21.6M |
| Gross Margin | 90.6% | — |
| Operating Margin | -608.9% | 38.5% |
| Net Margin | -541.1% | 54.9% |
| Revenue YoY | 86.1% | 1.1% |
| Net Profit YoY | -11.9% | 23.1% |
| EPS (diluted) | $-1.86 | $0.59 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $20.0M | $39.4M | ||
| Q3 25 | $12.9M | $39.8M | ||
| Q2 25 | $12.5M | $34.5M | ||
| Q1 25 | $8.7M | $42.6M | ||
| Q4 24 | $10.7M | $39.0M | ||
| Q3 24 | $9.0M | $30.1M | ||
| Q2 24 | $8.6M | $26.0M | ||
| Q1 24 | $8.2M | $30.3M |
| Q4 25 | $-108.0M | $21.6M | ||
| Q3 25 | $-103.4M | $16.0M | ||
| Q2 25 | $-112.0M | $19.6M | ||
| Q1 25 | $-89.3M | $13.0M | ||
| Q4 24 | $-96.5M | $17.6M | ||
| Q3 24 | $947.9M | $25.5M | ||
| Q2 24 | $-96.1M | $8.8M | ||
| Q1 24 | $-81.5M | $11.1M |
| Q4 25 | 90.6% | — | ||
| Q3 25 | 87.0% | — | ||
| Q2 25 | 86.3% | — | ||
| Q1 25 | 87.6% | — | ||
| Q4 24 | 88.3% | — | ||
| Q3 24 | 91.3% | — | ||
| Q2 24 | 82.6% | — | ||
| Q1 24 | 92.3% | — |
| Q4 25 | -608.9% | 38.5% | ||
| Q3 25 | -907.4% | 37.8% | ||
| Q2 25 | -1020.1% | 53.7% | ||
| Q1 25 | -1222.0% | 28.6% | ||
| Q4 24 | -1165.3% | 25.9% | ||
| Q3 24 | -1146.9% | 28.3% | ||
| Q2 24 | -1228.3% | 23.9% | ||
| Q1 24 | -1124.3% | 27.8% |
| Q4 25 | -541.1% | 54.9% | ||
| Q3 25 | -803.1% | 40.1% | ||
| Q2 25 | -899.4% | 56.6% | ||
| Q1 25 | -1023.3% | 30.6% | ||
| Q4 24 | -899.6% | 45.1% | ||
| Q3 24 | 10574.7% | 84.8% | ||
| Q2 24 | -1115.7% | 33.9% | ||
| Q1 24 | -995.8% | 36.7% |
| Q4 25 | $-1.86 | $0.59 | ||
| Q3 25 | $-1.78 | $0.43 | ||
| Q2 25 | $-1.93 | $0.53 | ||
| Q1 25 | $-1.55 | $0.35 | ||
| Q4 24 | $-1.44 | $0.46 | ||
| Q3 24 | $16.22 | $0.69 | ||
| Q2 24 | $-1.69 | $0.24 | ||
| Q1 24 | $-1.45 | $0.30 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.1M | $111.0M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $1.2B | $510.9M |
| Total Assets | $1.3B | $644.0M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $89.1M | $111.0M | ||
| Q3 25 | $92.7M | $101.2M | ||
| Q2 25 | $80.9M | $102.8M | ||
| Q1 25 | $79.0M | $99.7M | ||
| Q4 24 | $76.2M | $98.1M | ||
| Q3 24 | $253.7M | $92.7M | ||
| Q2 24 | $84.5M | $209.9M | ||
| Q1 24 | $118.8M | $207.0M |
| Q4 25 | $1.2B | $510.9M | ||
| Q3 25 | $1.3B | $492.4M | ||
| Q2 25 | $1.4B | $480.2M | ||
| Q1 25 | $1.5B | $464.9M | ||
| Q4 24 | $1.5B | $460.5M | ||
| Q3 24 | $1.6B | $446.8M | ||
| Q2 24 | $660.5M | $424.8M | ||
| Q1 24 | $743.9M | $419.7M |
| Q4 25 | $1.3B | $644.0M | ||
| Q3 25 | $1.4B | $619.0M | ||
| Q2 25 | $1.5B | $602.3M | ||
| Q1 25 | $1.6B | $588.3M | ||
| Q4 24 | $1.7B | $581.5M | ||
| Q3 24 | $1.8B | $565.2M | ||
| Q2 24 | $773.1M | $529.6M | ||
| Q1 24 | $849.7M | $527.4M |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-96.2M | $31.7M |
| Free Cash FlowOCF − Capex | $-97.3M | $14.4M |
| FCF MarginFCF / Revenue | -487.5% | 36.6% |
| Capex IntensityCapex / Revenue | 5.6% | 43.8% |
| Cash ConversionOCF / Net Profit | — | 1.46× |
| TTM Free Cash FlowTrailing 4 quarters | $-377.3M | $41.5M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-96.2M | $31.7M | ||
| Q3 25 | $-88.2M | $25.3M | ||
| Q2 25 | $-77.1M | $22.9M | ||
| Q1 25 | $-111.5M | $20.3M | ||
| Q4 24 | $-133.2M | $26.0M | ||
| Q3 24 | $-84.2M | $20.8M | ||
| Q2 24 | $-72.6M | $11.4M | ||
| Q1 24 | $-99.9M | $15.7M |
| Q4 25 | $-97.3M | $14.4M | ||
| Q3 25 | $-89.7M | $5.9M | ||
| Q2 25 | $-78.0M | $7.3M | ||
| Q1 25 | $-112.3M | $13.9M | ||
| Q4 24 | $-134.1M | $13.2M | ||
| Q3 24 | $-84.6M | $10.8M | ||
| Q2 24 | $-72.7M | $9.0M | ||
| Q1 24 | $-100.0M | $14.6M |
| Q4 25 | -487.5% | 36.6% | ||
| Q3 25 | -696.5% | 14.9% | ||
| Q2 25 | -626.2% | 21.0% | ||
| Q1 25 | -1286.4% | 32.7% | ||
| Q4 24 | -1250.1% | 33.8% | ||
| Q3 24 | -944.2% | 36.1% | ||
| Q2 24 | -844.4% | 34.5% | ||
| Q1 24 | -1221.2% | 48.1% |
| Q4 25 | 5.6% | 43.8% | ||
| Q3 25 | 12.1% | 48.6% | ||
| Q2 25 | 7.0% | 45.2% | ||
| Q1 25 | 8.8% | 15.0% | ||
| Q4 24 | 9.0% | 32.9% | ||
| Q3 24 | 4.7% | 33.3% | ||
| Q2 24 | 1.8% | 9.4% | ||
| Q1 24 | 1.7% | 3.7% |
| Q4 25 | — | 1.46× | ||
| Q3 25 | — | 1.58× | ||
| Q2 25 | — | 1.17× | ||
| Q1 25 | — | 1.56× | ||
| Q4 24 | — | 1.48× | ||
| Q3 24 | -0.09× | 0.82× | ||
| Q2 24 | — | 1.30× | ||
| Q1 24 | — | 1.41× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AGIO
Segment breakdown not available.
SD
| Oil Reserves | $19.0M | 48% |
| Natural Gas Reserves | $11.6M | 30% |
| Natural Gas Liquids Reserves | $8.7M | 22% |
