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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and Seaport Entertainment Group Inc. (SEG). Click either name above to swap in a different company.
Seaport Entertainment Group Inc. is the larger business by last-quarter revenue ($29.5M vs $20.0M, roughly 1.5× AGIOS PHARMACEUTICALS, INC.). Seaport Entertainment Group Inc. runs the higher net margin — -125.0% vs -541.1%, a 416.1% gap on every dollar of revenue.
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
AGIO vs SEG — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $20.0M | $29.5M |
| Net Profit | $-108.0M | $-36.9M |
| Gross Margin | 90.6% | — |
| Operating Margin | -608.9% | -120.5% |
| Net Margin | -541.1% | -125.0% |
| Revenue YoY | 86.1% | — |
| Net Profit YoY | -11.9% | — |
| EPS (diluted) | $-1.86 | $-2.90 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $20.0M | $29.5M | ||
| Q3 25 | $12.9M | $45.0M | ||
| Q2 25 | $12.5M | $39.8M | ||
| Q1 25 | $8.7M | $16.1M | ||
| Q4 24 | $10.7M | — | ||
| Q3 24 | $9.0M | $39.4M | ||
| Q2 24 | $8.6M | $33.7M | ||
| Q1 24 | $8.2M | — |
| Q4 25 | $-108.0M | $-36.9M | ||
| Q3 25 | $-103.4M | $-33.2M | ||
| Q2 25 | $-112.0M | $-14.8M | ||
| Q1 25 | $-89.3M | $-31.9M | ||
| Q4 24 | $-96.5M | — | ||
| Q3 24 | $947.9M | $-32.5M | ||
| Q2 24 | $-96.1M | $-35.0M | ||
| Q1 24 | $-81.5M | — |
| Q4 25 | 90.6% | — | ||
| Q3 25 | 87.0% | — | ||
| Q2 25 | 86.3% | — | ||
| Q1 25 | 87.6% | — | ||
| Q4 24 | 88.3% | — | ||
| Q3 24 | 91.3% | — | ||
| Q2 24 | 82.6% | — | ||
| Q1 24 | 92.3% | — |
| Q4 25 | -608.9% | -120.5% | ||
| Q3 25 | -907.4% | -75.2% | ||
| Q2 25 | -1020.1% | -40.2% | ||
| Q1 25 | -1222.0% | -203.5% | ||
| Q4 24 | -1165.3% | — | ||
| Q3 24 | -1146.9% | -51.0% | ||
| Q2 24 | -1228.3% | -75.3% | ||
| Q1 24 | -1124.3% | — |
| Q4 25 | -541.1% | -125.0% | ||
| Q3 25 | -803.1% | -73.7% | ||
| Q2 25 | -899.4% | -37.1% | ||
| Q1 25 | -1023.3% | -198.4% | ||
| Q4 24 | -899.6% | — | ||
| Q3 24 | 10574.7% | -82.5% | ||
| Q2 24 | -1115.7% | -103.9% | ||
| Q1 24 | -995.8% | — |
| Q4 25 | $-1.86 | $-2.90 | ||
| Q3 25 | $-1.78 | $-2.61 | ||
| Q2 25 | $-1.93 | $-1.16 | ||
| Q1 25 | $-1.55 | $-2.51 | ||
| Q4 24 | $-1.44 | — | ||
| Q3 24 | $16.22 | $-5.89 | ||
| Q2 24 | $-1.69 | $-6.34 | ||
| Q1 24 | $-1.45 | — |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.1M | $77.8M |
| Total DebtLower is stronger | — | $38.3M |
| Stockholders' EquityBook value | $1.2B | $456.5M |
| Total Assets | $1.3B | $650.1M |
| Debt / EquityLower = less leverage | — | 0.08× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $89.1M | $77.8M | ||
| Q3 25 | $92.7M | $106.2M | ||
| Q2 25 | $80.9M | $123.3M | ||
| Q1 25 | $79.0M | $129.9M | ||
| Q4 24 | $76.2M | — | ||
| Q3 24 | $253.7M | $23.7M | ||
| Q2 24 | $84.5M | $3.3M | ||
| Q1 24 | $118.8M | — |
| Q4 25 | — | $38.3M | ||
| Q3 25 | — | $39.3M | ||
| Q2 25 | — | $100.6M | ||
| Q1 25 | — | $101.6M | ||
| Q4 24 | — | — | ||
| Q3 24 | — | $103.3M | ||
| Q2 24 | — | $157.1M | ||
| Q1 24 | — | — |
| Q4 25 | $1.2B | $456.5M | ||
| Q3 25 | $1.3B | $485.8M | ||
| Q2 25 | $1.4B | $517.9M | ||
| Q1 25 | $1.5B | $531.2M | ||
| Q4 24 | $1.5B | — | ||
| Q3 24 | $1.6B | $433.8M | ||
| Q2 24 | $660.5M | $380.7M | ||
| Q1 24 | $743.9M | — |
| Q4 25 | $1.3B | $650.1M | ||
| Q3 25 | $1.4B | $699.1M | ||
| Q2 25 | $1.5B | $717.2M | ||
| Q1 25 | $1.6B | $718.4M | ||
| Q4 24 | $1.7B | — | ||
| Q3 24 | $1.8B | $622.8M | ||
| Q2 24 | $773.1M | $610.1M | ||
| Q1 24 | $849.7M | — |
| Q4 25 | — | 0.08× | ||
| Q3 25 | — | 0.08× | ||
| Q2 25 | — | 0.19× | ||
| Q1 25 | — | 0.19× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 0.24× | ||
| Q2 24 | — | 0.41× | ||
| Q1 24 | — | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-96.2M | $-23.1M |
| Free Cash FlowOCF − Capex | $-97.3M | — |
| FCF MarginFCF / Revenue | -487.5% | — |
| Capex IntensityCapex / Revenue | 5.6% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-377.3M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-96.2M | $-23.1M | ||
| Q3 25 | $-88.2M | $-5.3M | ||
| Q2 25 | $-77.1M | $-754.0K | ||
| Q1 25 | $-111.5M | $-20.5M | ||
| Q4 24 | $-133.2M | — | ||
| Q3 24 | $-84.2M | $-8.8M | ||
| Q2 24 | $-72.6M | — | ||
| Q1 24 | $-99.9M | — |
| Q4 25 | $-97.3M | — | ||
| Q3 25 | $-89.7M | — | ||
| Q2 25 | $-78.0M | — | ||
| Q1 25 | $-112.3M | — | ||
| Q4 24 | $-134.1M | — | ||
| Q3 24 | $-84.6M | — | ||
| Q2 24 | $-72.7M | — | ||
| Q1 24 | $-100.0M | — |
| Q4 25 | -487.5% | — | ||
| Q3 25 | -696.5% | — | ||
| Q2 25 | -626.2% | — | ||
| Q1 25 | -1286.4% | — | ||
| Q4 24 | -1250.1% | — | ||
| Q3 24 | -944.2% | — | ||
| Q2 24 | -844.4% | — | ||
| Q1 24 | -1221.2% | — |
| Q4 25 | 5.6% | — | ||
| Q3 25 | 12.1% | — | ||
| Q2 25 | 7.0% | — | ||
| Q1 25 | 8.8% | — | ||
| Q4 24 | 9.0% | — | ||
| Q3 24 | 4.7% | — | ||
| Q2 24 | 1.8% | — | ||
| Q1 24 | 1.7% | — |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | -0.09× | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AGIO
Segment breakdown not available.
SEG
| Sponsorships Events And Entertainment | $12.5M | 43% |
| Hospitality | $12.2M | 41% |
| Rental | $4.1M | 14% |
| Other | $631.0K | 2% |
