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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and SIFCO INDUSTRIES INC (SIF). Click either name above to swap in a different company.
SIFCO INDUSTRIES INC is the larger business by last-quarter revenue ($24.0M vs $20.0M, roughly 1.2× AGIOS PHARMACEUTICALS, INC.). SIFCO INDUSTRIES INC runs the higher net margin — 7.5% vs -541.1%, a 548.6% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs 14.8%). SIFCO INDUSTRIES INC produced more free cash flow last quarter ($8.0M vs $-97.3M). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs 8.1%).
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
SIFCO Industries, Inc. (SIFCO), is a global metal component manufacturer based in Cleveland, Ohio.
AGIO vs SIF — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $20.0M | $24.0M |
| Net Profit | $-108.0M | $1.8M |
| Gross Margin | 90.6% | 21.6% |
| Operating Margin | -608.9% | 10.7% |
| Net Margin | -541.1% | 7.5% |
| Revenue YoY | 86.1% | 14.8% |
| Net Profit YoY | -11.9% | 177.3% |
| EPS (diluted) | $-1.86 | $0.29 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $20.0M | $24.0M | ||
| Q3 25 | $12.9M | $22.8M | ||
| Q2 25 | $12.5M | $22.1M | ||
| Q1 25 | $8.7M | $19.0M | ||
| Q4 24 | $10.7M | $20.9M | ||
| Q3 24 | $9.0M | $21.7M | ||
| Q2 24 | $8.6M | $22.0M | ||
| Q1 24 | $8.2M | $20.5M |
| Q4 25 | $-108.0M | $1.8M | ||
| Q3 25 | $-103.4M | $-429.0K | ||
| Q2 25 | $-112.0M | $3.4M | ||
| Q1 25 | $-89.3M | $-1.4M | ||
| Q4 24 | $-96.5M | $-2.3M | ||
| Q3 24 | $947.9M | $-443.0K | ||
| Q2 24 | $-96.1M | $72.0K | ||
| Q1 24 | $-81.5M | $-1.6M |
| Q4 25 | 90.6% | 21.6% | ||
| Q3 25 | 87.0% | 9.6% | ||
| Q2 25 | 86.3% | 26.7% | ||
| Q1 25 | 87.6% | 8.3% | ||
| Q4 24 | 88.3% | 4.4% | ||
| Q3 24 | 91.3% | 10.7% | ||
| Q2 24 | 82.6% | 12.3% | ||
| Q1 24 | 92.3% | 7.3% |
| Q4 25 | -608.9% | 10.7% | ||
| Q3 25 | -907.4% | -1.7% | ||
| Q2 25 | -1020.1% | 14.8% | ||
| Q1 25 | -1222.0% | -4.1% | ||
| Q4 24 | -1165.3% | -9.2% | ||
| Q3 24 | -1146.9% | -1.5% | ||
| Q2 24 | -1228.3% | 0.7% | ||
| Q1 24 | -1124.3% | -6.5% |
| Q4 25 | -541.1% | 7.5% | ||
| Q3 25 | -803.1% | -1.9% | ||
| Q2 25 | -899.4% | 15.4% | ||
| Q1 25 | -1023.3% | -7.3% | ||
| Q4 24 | -899.6% | -11.1% | ||
| Q3 24 | 10574.7% | -2.0% | ||
| Q2 24 | -1115.7% | 0.3% | ||
| Q1 24 | -995.8% | -7.8% |
| Q4 25 | $-1.86 | $0.29 | ||
| Q3 25 | $-1.78 | $-0.07 | ||
| Q2 25 | $-1.93 | $0.56 | ||
| Q1 25 | $-1.55 | $-0.23 | ||
| Q4 24 | $-1.44 | $-0.38 | ||
| Q3 24 | $16.22 | $-0.07 | ||
| Q2 24 | $-1.69 | $0.01 | ||
| Q1 24 | $-1.45 | $-0.27 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.1M | $1.1M |
| Total DebtLower is stronger | — | $39.0K |
| Stockholders' EquityBook value | $1.2B | $38.7M |
| Total Assets | $1.3B | $74.9M |
| Debt / EquityLower = less leverage | — | 0.00× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $89.1M | $1.1M | ||
| Q3 25 | $92.7M | $491.0K | ||
| Q2 25 | $80.9M | $2.0M | ||
| Q1 25 | $79.0M | $1.9M | ||
| Q4 24 | $76.2M | $3.1M | ||
| Q3 24 | $253.7M | $1.7M | ||
| Q2 24 | $84.5M | $3.4M | ||
| Q1 24 | $118.8M | $2.5M |
| Q4 25 | — | $39.0K | ||
| Q3 25 | — | $51.0K | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | $0 | ||
| Q2 24 | — | $3.6M | ||
| Q1 24 | — | $4.1M |
| Q4 25 | $1.2B | $38.7M | ||
| Q3 25 | $1.3B | $36.9M | ||
| Q2 25 | $1.4B | $35.8M | ||
| Q1 25 | $1.5B | $32.4M | ||
| Q4 24 | $1.5B | $33.7M | ||
| Q3 24 | $1.6B | $30.4M | ||
| Q2 24 | $660.5M | $29.8M | ||
| Q1 24 | $743.9M | $29.7M |
| Q4 25 | $1.3B | $74.9M | ||
| Q3 25 | $1.4B | $73.4M | ||
| Q2 25 | $1.5B | $77.3M | ||
| Q1 25 | $1.6B | $78.8M | ||
| Q4 24 | $1.7B | $81.0M | ||
| Q3 24 | $1.8B | $104.6M | ||
| Q2 24 | $773.1M | $106.3M | ||
| Q1 24 | $849.7M | $104.2M |
| Q4 25 | — | 0.00× | ||
| Q3 25 | — | 0.00× | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 0.00× | ||
| Q2 24 | — | 0.12× | ||
| Q1 24 | — | 0.14× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-96.2M | $8.1M |
| Free Cash FlowOCF − Capex | $-97.3M | $8.0M |
| FCF MarginFCF / Revenue | -487.5% | 33.3% |
| Capex IntensityCapex / Revenue | 5.6% | 0.4% |
| Cash ConversionOCF / Net Profit | — | 4.51× |
| TTM Free Cash FlowTrailing 4 quarters | $-377.3M | $11.5M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-96.2M | $8.1M | ||
| Q3 25 | $-88.2M | $726.0K | ||
| Q2 25 | $-77.1M | $371.0K | ||
| Q1 25 | $-111.5M | $2.8M | ||
| Q4 24 | $-133.2M | $-3.8M | ||
| Q3 24 | $-84.2M | $857.0K | ||
| Q2 24 | $-72.6M | $382.0K | ||
| Q1 24 | $-99.9M | $-3.2M |
| Q4 25 | $-97.3M | $8.0M | ||
| Q3 25 | $-89.7M | $566.0K | ||
| Q2 25 | $-78.0M | $310.0K | ||
| Q1 25 | $-112.3M | $2.7M | ||
| Q4 24 | $-134.1M | $-3.9M | ||
| Q3 24 | $-84.6M | $580.0K | ||
| Q2 24 | $-72.7M | $-175.0K | ||
| Q1 24 | $-100.0M | $-3.9M |
| Q4 25 | -487.5% | 33.3% | ||
| Q3 25 | -696.5% | 2.5% | ||
| Q2 25 | -626.2% | 1.4% | ||
| Q1 25 | -1286.4% | 14.1% | ||
| Q4 24 | -1250.1% | -18.8% | ||
| Q3 24 | -944.2% | 2.7% | ||
| Q2 24 | -844.4% | -0.8% | ||
| Q1 24 | -1221.2% | -18.9% |
| Q4 25 | 5.6% | 0.4% | ||
| Q3 25 | 12.1% | 0.7% | ||
| Q2 25 | 7.0% | 0.3% | ||
| Q1 25 | 8.8% | 0.8% | ||
| Q4 24 | 9.0% | 0.5% | ||
| Q3 24 | 4.7% | 1.3% | ||
| Q2 24 | 1.8% | 2.5% | ||
| Q1 24 | 1.7% | 3.3% |
| Q4 25 | — | 4.51× | ||
| Q3 25 | — | — | ||
| Q2 25 | — | 0.11× | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | -0.09× | — | ||
| Q2 24 | — | 5.31× | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AGIO
Segment breakdown not available.
SIF
| Fixed Wing Aircraft Revenue | $10.5M | 44% |
| Commercial Revenue | $8.7M | 36% |
| Commercial Product And Other Revenue | $2.8M | 12% |
| Commercial Space | $1.1M | 5% |
| Other | $840.0K | 4% |
