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Side-by-side financial comparison of AGIOS PHARMACEUTICALS, INC. (AGIO) and Zeo Energy Corp. (ZEO). Click either name above to swap in a different company.
AGIOS PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($20.0M vs $18.6M, roughly 1.1× Zeo Energy Corp.). Zeo Energy Corp. runs the higher net margin — -10.8% vs -541.1%, a 530.3% gap on every dollar of revenue. On growth, AGIOS PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (86.1% vs -0.4%). Zeo Energy Corp. produced more free cash flow last quarter ($2.3M vs $-97.3M). Over the past eight quarters, AGIOS PHARMACEUTICALS, INC.'s revenue compounded faster (56.1% CAGR vs -4.0%).
Agios Pharmaceuticals Inc. is a publicly trading American pharmaceutical company pioneering therapies for genetically defined diseases, with a near-term focus on developing therapies for hemolytic anemias. The company was founded in 2008 by Lewis Cantley, Tak Mak and Craig Thompson. Agios is a Delaware corporation headquartered in Cambridge, Massachusetts. The company tendered an initial public offering in July 2013.
AGIO vs ZEO — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $20.0M | $18.6M |
| Net Profit | $-108.0M | $-2.0M |
| Gross Margin | 90.6% | — |
| Operating Margin | -608.9% | -11.8% |
| Net Margin | -541.1% | -10.8% |
| Revenue YoY | 86.1% | -0.4% |
| Net Profit YoY | -11.9% | -360.9% |
| EPS (diluted) | $-1.86 | — |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $20.0M | $18.6M | ||
| Q3 25 | $12.9M | $23.9M | ||
| Q2 25 | $12.5M | $18.1M | ||
| Q1 25 | $8.7M | $8.8M | ||
| Q4 24 | $10.7M | $18.6M | ||
| Q3 24 | $9.0M | $19.7M | ||
| Q2 24 | $8.6M | $14.8M | ||
| Q1 24 | $8.2M | $20.1M |
| Q4 25 | $-108.0M | $-2.0M | ||
| Q3 25 | $-103.4M | $-3.2M | ||
| Q2 25 | $-112.0M | $-2.4M | ||
| Q1 25 | $-89.3M | $-6.4M | ||
| Q4 24 | $-96.5M | $-435.3K | ||
| Q3 24 | $947.9M | $-424.3K | ||
| Q2 24 | $-96.1M | $-277.8K | ||
| Q1 24 | $-81.5M | $-1.5M |
| Q4 25 | 90.6% | — | ||
| Q3 25 | 87.0% | 57.9% | ||
| Q2 25 | 86.3% | 59.8% | ||
| Q1 25 | 87.6% | 99.3% | ||
| Q4 24 | 88.3% | — | ||
| Q3 24 | 91.3% | 50.2% | ||
| Q2 24 | 82.6% | 52.3% | ||
| Q1 24 | 92.3% | — |
| Q4 25 | -608.9% | -11.8% | ||
| Q3 25 | -907.4% | -8.3% | ||
| Q2 25 | -1020.1% | -15.8% | ||
| Q1 25 | -1222.0% | -153.8% | ||
| Q4 24 | -1165.3% | -6.0% | ||
| Q3 24 | -1146.9% | -15.2% | ||
| Q2 24 | -1228.3% | -18.0% | ||
| Q1 24 | -1124.3% | -20.1% |
| Q4 25 | -541.1% | -10.8% | ||
| Q3 25 | -803.1% | -13.5% | ||
| Q2 25 | -899.4% | -13.3% | ||
| Q1 25 | -1023.3% | -72.4% | ||
| Q4 24 | -899.6% | -2.3% | ||
| Q3 24 | 10574.7% | -2.2% | ||
| Q2 24 | -1115.7% | -1.9% | ||
| Q1 24 | -995.8% | -7.6% |
| Q4 25 | $-1.86 | — | ||
| Q3 25 | $-1.78 | — | ||
| Q2 25 | $-1.93 | — | ||
| Q1 25 | $-1.55 | $-0.48 | ||
| Q4 24 | $-1.44 | $1.11 | ||
| Q3 24 | $16.22 | $-0.08 | ||
| Q2 24 | $-1.69 | $0.03 | ||
| Q1 24 | $-1.45 | $-1.54 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $89.1M | $6.1M |
| Total DebtLower is stronger | — | $79.1K |
| Stockholders' EquityBook value | $1.2B | $5.3M |
| Total Assets | $1.3B | $56.9M |
| Debt / EquityLower = less leverage | — | 0.01× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $89.1M | $6.1M | ||
| Q3 25 | $92.7M | $3.9M | ||
| Q2 25 | $80.9M | $68.7K | ||
| Q1 25 | $79.0M | $2.9M | ||
| Q4 24 | $76.2M | $5.6M | ||
| Q3 24 | $253.7M | $4.3M | ||
| Q2 24 | $84.5M | $5.3M | ||
| Q1 24 | $118.8M | — |
| Q4 25 | — | $79.1K | ||
| Q3 25 | — | $84.6K | ||
| Q2 25 | — | $642.8K | ||
| Q1 25 | — | $715.4K | ||
| Q4 24 | — | $787.7K | ||
| Q3 24 | — | $858.6K | ||
| Q2 24 | — | $1.6M | ||
| Q1 24 | — | $748.8K |
| Q4 25 | $1.2B | $5.3M | ||
| Q3 25 | $1.3B | $-1.7M | ||
| Q2 25 | $1.4B | $-59.4M | ||
| Q1 25 | $1.5B | $-23.1M | ||
| Q4 24 | $1.5B | $-88.9M | ||
| Q3 24 | $1.6B | $-39.3M | ||
| Q2 24 | $660.5M | $-53.0M | ||
| Q1 24 | $743.9M | $-173.0M |
| Q4 25 | $1.3B | $56.9M | ||
| Q3 25 | $1.4B | $58.5M | ||
| Q2 25 | $1.5B | $46.2M | ||
| Q1 25 | $1.6B | $47.4M | ||
| Q4 24 | $1.7B | $61.0M | ||
| Q3 24 | $1.8B | $47.1M | ||
| Q2 24 | $773.1M | $49.1M | ||
| Q1 24 | $849.7M | $50.1M |
| Q4 25 | — | 0.01× | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-96.2M | $2.4M |
| Free Cash FlowOCF − Capex | $-97.3M | $2.3M |
| FCF MarginFCF / Revenue | -487.5% | 12.2% |
| Capex IntensityCapex / Revenue | 5.6% | 0.9% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-377.3M | $-9.9M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-96.2M | $2.4M | ||
| Q3 25 | $-88.2M | $-6.6M | ||
| Q2 25 | $-77.1M | $-2.3M | ||
| Q1 25 | $-111.5M | $-2.3M | ||
| Q4 24 | $-133.2M | $3.5M | ||
| Q3 24 | $-84.2M | $162.2K | ||
| Q2 24 | $-72.6M | $-2.2M | ||
| Q1 24 | $-99.9M | $-10.2M |
| Q4 25 | $-97.3M | $2.3M | ||
| Q3 25 | $-89.7M | $-6.8M | ||
| Q2 25 | $-78.0M | $-2.7M | ||
| Q1 25 | $-112.3M | $-2.6M | ||
| Q4 24 | $-134.1M | $3.4M | ||
| Q3 24 | $-84.6M | $116.5K | ||
| Q2 24 | $-72.7M | $-2.3M | ||
| Q1 24 | $-100.0M | $-10.4M |
| Q4 25 | -487.5% | 12.2% | ||
| Q3 25 | -696.5% | -28.6% | ||
| Q2 25 | -626.2% | -15.0% | ||
| Q1 25 | -1286.4% | -30.0% | ||
| Q4 24 | -1250.1% | 18.2% | ||
| Q3 24 | -944.2% | 0.6% | ||
| Q2 24 | -844.4% | -15.6% | ||
| Q1 24 | -1221.2% | -51.5% |
| Q4 25 | 5.6% | 0.9% | ||
| Q3 25 | 12.1% | 1.0% | ||
| Q2 25 | 7.0% | 2.4% | ||
| Q1 25 | 8.8% | 4.2% | ||
| Q4 24 | 9.0% | 0.5% | ||
| Q3 24 | 4.7% | 0.2% | ||
| Q2 24 | 1.8% | 0.7% | ||
| Q1 24 | 1.7% | 1.1% |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | -0.09× | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AGIO
Segment breakdown not available.
ZEO
| Nonrelated Party | $18.1M | 98% |
| Related Party | $432.1K | 2% |
