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Side-by-side financial comparison of Align Technology (ALGN) and Cellectis S.A. (CLLS). Click either name above to swap in a different company.

Align Technology is the larger business by last-quarter revenue ($1.0B vs $9.5M, roughly 110.2× Cellectis S.A.). Align Technology runs the higher net margin — 13.0% vs -265.9%, a 278.8% gap on every dollar of revenue. On growth, Cellectis S.A. posted the faster year-over-year revenue change (375.0% vs 5.3%). Align Technology produced more free cash flow last quarter ($187.3M vs $27.6M).

Align Technology, Inc., a medical device company, designs, manufactures, and markets Invisalign clear aligners and iTero intraoral scanners and services for orthodontists and general practitioner dentists, and restorative and aesthetic dentistry. It operates in two segments, Clear Aligner; and Scanners and Services. The Clear Aligner segment consists of comprehensive products, including Invisalign comprehensive treatment that addresses the orthodontic needs of teenage patients, such as mandib...

Cellectis is a French biopharmaceutical company. It develops genome-edited chimeric antigen receptor T-cell technologies for cancer immunotherapy. It has offices in Paris, New York City, and Raleigh, North Carolina.

ALGN vs CLLS — Head-to-Head

Bigger by revenue
ALGN
ALGN
110.2× larger
ALGN
$1.0B
$9.5M
CLLS
Growing faster (revenue YoY)
CLLS
CLLS
+369.7% gap
CLLS
375.0%
5.3%
ALGN
Higher net margin
ALGN
ALGN
278.8% more per $
ALGN
13.0%
-265.9%
CLLS
More free cash flow
ALGN
ALGN
$159.7M more FCF
ALGN
$187.3M
$27.6M
CLLS

Income Statement — Q4 2025 vs Q2 2024

Metric
ALGN
ALGN
CLLS
CLLS
Revenue
$1.0B
$9.5M
Net Profit
$135.8M
$-25.3M
Gross Margin
65.3%
Operating Margin
14.8%
-181.1%
Net Margin
13.0%
-265.9%
Revenue YoY
5.3%
375.0%
Net Profit YoY
30.8%
-51.9%
EPS (diluted)
$1.88
$-0.28

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ALGN
ALGN
CLLS
CLLS
Q4 25
$1.0B
Q3 25
$995.7M
Q2 25
$1.0B
Q1 25
$979.3M
Q4 24
$995.2M
Q3 24
$977.9M
Q2 24
$1.0B
$9.5M
Q1 24
$997.4M
Net Profit
ALGN
ALGN
CLLS
CLLS
Q4 25
$135.8M
Q3 25
$56.8M
Q2 25
$124.6M
Q1 25
$93.2M
Q4 24
$103.8M
Q3 24
$116.0M
Q2 24
$96.6M
$-25.3M
Q1 24
$105.0M
Gross Margin
ALGN
ALGN
CLLS
CLLS
Q4 25
65.3%
Q3 25
64.2%
Q2 25
69.9%
Q1 25
69.5%
Q4 24
70.0%
Q3 24
69.7%
Q2 24
70.3%
Q1 24
70.0%
Operating Margin
ALGN
ALGN
CLLS
CLLS
Q4 25
14.8%
Q3 25
9.7%
Q2 25
16.1%
Q1 25
13.4%
Q4 24
14.5%
Q3 24
16.6%
Q2 24
14.3%
-181.1%
Q1 24
15.5%
Net Margin
ALGN
ALGN
CLLS
CLLS
Q4 25
13.0%
Q3 25
5.7%
Q2 25
12.3%
Q1 25
9.5%
Q4 24
10.4%
Q3 24
11.9%
Q2 24
9.4%
-265.9%
Q1 24
10.5%
EPS (diluted)
ALGN
ALGN
CLLS
CLLS
Q4 25
$1.88
Q3 25
$0.78
Q2 25
$1.72
Q1 25
$1.27
Q4 24
$1.40
Q3 24
$1.55
Q2 24
$1.28
$-0.28
Q1 24
$1.39

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ALGN
ALGN
CLLS
CLLS
Cash + ST InvestmentsLiquidity on hand
$1.1B
$149.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$4.0B
$148.6M
Total Assets
$6.2B
$407.1M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ALGN
ALGN
CLLS
CLLS
Q4 25
$1.1B
Q3 25
$1.0B
Q2 25
$901.2M
Q1 25
$873.0M
Q4 24
$1.0B
Q3 24
$1.0B
Q2 24
$761.4M
$149.0M
Q1 24
$865.8M
Stockholders' Equity
ALGN
ALGN
CLLS
CLLS
Q4 25
$4.0B
Q3 25
$4.0B
Q2 25
$3.9B
Q1 25
$3.8B
Q4 24
$3.9B
Q3 24
$3.9B
Q2 24
$3.8B
$148.6M
Q1 24
$3.8B
Total Assets
ALGN
ALGN
CLLS
CLLS
Q4 25
$6.2B
Q3 25
$6.2B
Q2 25
$6.2B
Q1 25
$6.1B
Q4 24
$6.2B
Q3 24
$6.4B
Q2 24
$6.2B
$407.1M
Q1 24
$6.2B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ALGN
ALGN
CLLS
CLLS
Operating Cash FlowLast quarter
$223.2M
$28.9M
Free Cash FlowOCF − Capex
$187.3M
$27.6M
FCF MarginFCF / Revenue
17.9%
290.5%
Capex IntensityCapex / Revenue
3.4%
13.2%
Cash ConversionOCF / Net Profit
1.64×
TTM Free Cash FlowTrailing 4 quarters
$490.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ALGN
ALGN
CLLS
CLLS
Q4 25
$223.2M
Q3 25
$188.7M
Q2 25
$128.7M
Q1 25
$52.7M
Q4 24
$286.1M
Q3 24
$263.7M
Q2 24
$159.8M
$28.9M
Q1 24
$28.7M
Free Cash Flow
ALGN
ALGN
CLLS
CLLS
Q4 25
$187.3M
Q3 25
$169.0M
Q2 25
$107.2M
Q1 25
$27.4M
Q4 24
$263.1M
Q3 24
$233.9M
Q2 24
$106.4M
$27.6M
Q1 24
$19.3M
FCF Margin
ALGN
ALGN
CLLS
CLLS
Q4 25
17.9%
Q3 25
17.0%
Q2 25
10.6%
Q1 25
2.8%
Q4 24
26.4%
Q3 24
23.9%
Q2 24
10.3%
290.5%
Q1 24
1.9%
Capex Intensity
ALGN
ALGN
CLLS
CLLS
Q4 25
3.4%
Q3 25
2.0%
Q2 25
2.1%
Q1 25
2.6%
Q4 24
2.3%
Q3 24
3.0%
Q2 24
5.2%
13.2%
Q1 24
0.9%
Cash Conversion
ALGN
ALGN
CLLS
CLLS
Q4 25
1.64×
Q3 25
3.33×
Q2 25
1.03×
Q1 25
0.57×
Q4 24
2.76×
Q3 24
2.27×
Q2 24
1.66×
Q1 24
0.27×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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