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Side-by-side financial comparison of Alkermes plc. (ALKS) and BeOne Medicines Ltd. (ONC). Click either name above to swap in a different company.

BeOne Medicines Ltd. is the larger business by last-quarter revenue ($1.5B vs $384.5M, roughly 3.9× Alkermes plc.). Alkermes plc. runs the higher net margin — 12.8% vs 4.4%, a 8.4% gap on every dollar of revenue. On growth, BeOne Medicines Ltd. posted the faster year-over-year revenue change (32.8% vs -10.6%). BeOne Medicines Ltd. produced more free cash flow last quarter ($379.8M vs $170.0M). Over the past eight quarters, BeOne Medicines Ltd.'s revenue compounded faster (41.2% CAGR vs 4.8%).

Alkermes plc is a fully-integrated biopharmaceutical company that focuses on developing medicines for psychiatric and neurological disorders. The company was founded in 1987 by Michael Wall. In September 2011 Alkermes, Inc. merged with Elan Drug Technologies (EDT), the former drug formulation and manufacturing division of Élan Corporation, plc. The company is headquartered in Dublin, and has an R&D center in Waltham, Massachusetts, and a manufacturing facility in Wilmington, Ohio.

BeOne Medicines, formerly known as BeiGene, Ltd. is a multinational oncology company. It specializes in the development of drugs for cancer treatment.

ALKS vs ONC — Head-to-Head

Bigger by revenue
ONC
ONC
3.9× larger
ONC
$1.5B
$384.5M
ALKS
Growing faster (revenue YoY)
ONC
ONC
+43.4% gap
ONC
32.8%
-10.6%
ALKS
Higher net margin
ALKS
ALKS
8.4% more per $
ALKS
12.8%
4.4%
ONC
More free cash flow
ONC
ONC
$209.8M more FCF
ONC
$379.8M
$170.0M
ALKS
Faster 2-yr revenue CAGR
ONC
ONC
Annualised
ONC
41.2%
4.8%
ALKS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ALKS
ALKS
ONC
ONC
Revenue
$384.5M
$1.5B
Net Profit
$49.3M
$66.5M
Gross Margin
88.0%
90.5%
Operating Margin
15.1%
12.4%
Net Margin
12.8%
4.4%
Revenue YoY
-10.6%
32.8%
Net Profit YoY
-66.3%
143.8%
EPS (diluted)
$0.29
$0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ALKS
ALKS
ONC
ONC
Q4 25
$384.5M
$1.5B
Q3 25
$394.2M
$1.4B
Q2 25
$390.7M
$1.3B
Q1 25
$306.5M
$1.1B
Q4 24
$430.0M
$1.1B
Q3 24
$378.1M
$1.0B
Q2 24
$399.1M
$929.2M
Q1 24
$350.4M
$751.7M
Net Profit
ALKS
ALKS
ONC
ONC
Q4 25
$49.3M
$66.5M
Q3 25
$82.8M
$124.8M
Q2 25
$87.1M
$94.3M
Q1 25
$22.5M
$1.3M
Q4 24
$146.5M
$-151.9M
Q3 24
$92.4M
$-121.3M
Q2 24
$91.4M
$-120.4M
Q1 24
$36.8M
$-251.2M
Gross Margin
ALKS
ALKS
ONC
ONC
Q4 25
88.0%
90.5%
Q3 25
86.9%
86.1%
Q2 25
87.3%
87.5%
Q1 25
83.9%
85.2%
Q4 24
85.6%
85.8%
Q3 24
83.3%
83.0%
Q2 24
84.6%
85.1%
Q1 24
83.3%
83.4%
Operating Margin
ALKS
ALKS
ONC
ONC
Q4 25
15.1%
12.4%
Q3 25
22.6%
11.5%
Q2 25
23.8%
6.7%
Q1 25
4.5%
1.0%
Q4 24
37.8%
-7.0%
Q3 24
27.7%
-12.0%
Q2 24
27.5%
-11.5%
Q1 24
12.4%
-34.8%
Net Margin
ALKS
ALKS
ONC
ONC
Q4 25
12.8%
4.4%
Q3 25
21.0%
8.8%
Q2 25
22.3%
7.2%
Q1 25
7.3%
0.1%
Q4 24
34.1%
-13.5%
Q3 24
24.4%
-12.1%
Q2 24
22.9%
-13.0%
Q1 24
10.5%
-33.4%
EPS (diluted)
ALKS
ALKS
ONC
ONC
Q4 25
$0.29
$0.05
Q3 25
$0.49
$0.08
Q2 25
$0.52
$0.06
Q1 25
$0.13
$0.00
Q4 24
$0.88
$-0.10
Q3 24
$0.55
$-0.09
Q2 24
$0.53
$-0.09
Q1 24
$0.21
$-0.19

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ALKS
ALKS
ONC
ONC
Cash + ST InvestmentsLiquidity on hand
$388.6M
$4.5B
Total DebtLower is stronger
$836.4M
Stockholders' EquityBook value
$1.8B
$4.4B
Total Assets
$2.5B
$8.2B
Debt / EquityLower = less leverage
0.19×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ALKS
ALKS
ONC
ONC
Q4 25
$388.6M
$4.5B
Q3 25
$616.4M
$4.0B
Q2 25
$521.2M
$2.8B
Q1 25
$399.8M
$2.5B
Q4 24
$291.1M
$2.6B
Q3 24
$396.3M
$2.7B
Q2 24
$535.1M
$2.6B
Q1 24
$420.8M
$2.8B
Total Debt
ALKS
ALKS
ONC
ONC
Q4 25
$836.4M
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Stockholders' Equity
ALKS
ALKS
ONC
ONC
Q4 25
$1.8B
$4.4B
Q3 25
$1.7B
$4.1B
Q2 25
$1.6B
$3.8B
Q1 25
$1.5B
$3.5B
Q4 24
$1.5B
$3.3B
Q3 24
$1.3B
$3.4B
Q2 24
$1.3B
$3.4B
Q1 24
$1.3B
$3.4B
Total Assets
ALKS
ALKS
ONC
ONC
Q4 25
$2.5B
$8.2B
Q3 25
$2.3B
$7.6B
Q2 25
$2.3B
$6.3B
Q1 25
$2.1B
$5.8B
Q4 24
$2.1B
$5.9B
Q3 24
$2.2B
$5.8B
Q2 24
$2.2B
$5.7B
Q1 24
$2.1B
$5.7B
Debt / Equity
ALKS
ALKS
ONC
ONC
Q4 25
0.19×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ALKS
ALKS
ONC
ONC
Operating Cash FlowLast quarter
$170.1M
$417.3M
Free Cash FlowOCF − Capex
$170.0M
$379.8M
FCF MarginFCF / Revenue
44.2%
25.4%
Capex IntensityCapex / Revenue
0.0%
2.5%
Cash ConversionOCF / Net Profit
3.45×
6.28×
TTM Free Cash FlowTrailing 4 quarters
$480.3M
$941.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ALKS
ALKS
ONC
ONC
Q4 25
$170.1M
$417.3M
Q3 25
$101.7M
$402.6M
Q2 25
$150.2M
$263.6M
Q1 25
$98.8M
$44.1M
Q4 24
$190.4M
$75.2M
Q3 24
$81.6M
$188.4M
Q2 24
$146.0M
$-95.6M
Q1 24
$21.1M
$-308.6M
Free Cash Flow
ALKS
ALKS
ONC
ONC
Q4 25
$170.0M
$379.8M
Q3 25
$84.4M
$354.5M
Q2 25
$137.2M
$219.8M
Q1 25
$88.7M
$-12.3M
Q4 24
$180.6M
$-17.3M
Q3 24
$73.3M
$54.7M
Q2 24
$138.9M
$-205.5M
Q1 24
$12.8M
$-465.1M
FCF Margin
ALKS
ALKS
ONC
ONC
Q4 25
44.2%
25.4%
Q3 25
21.4%
25.1%
Q2 25
35.1%
16.7%
Q1 25
28.9%
-1.1%
Q4 24
42.0%
-1.5%
Q3 24
19.4%
5.5%
Q2 24
34.8%
-22.1%
Q1 24
3.6%
-61.9%
Capex Intensity
ALKS
ALKS
ONC
ONC
Q4 25
0.0%
2.5%
Q3 25
4.4%
3.4%
Q2 25
3.3%
3.3%
Q1 25
3.3%
5.0%
Q4 24
2.3%
8.2%
Q3 24
2.2%
13.3%
Q2 24
1.8%
11.8%
Q1 24
2.4%
20.8%
Cash Conversion
ALKS
ALKS
ONC
ONC
Q4 25
3.45×
6.28×
Q3 25
1.23×
3.22×
Q2 25
1.72×
2.79×
Q1 25
4.40×
34.71×
Q4 24
1.30×
Q3 24
0.88×
Q2 24
1.60×
Q1 24
0.57×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ALKS
ALKS

Vivitrol$124.1M32%
Aristada And Aristada Initio$97.2M25%
LYBALVI$94.1M24%
Royalty$65.7M17%
Manufacturing Revenue$3.3M1%

ONC
ONC

Segment breakdown not available.

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