vs

Side-by-side financial comparison of BeOne Medicines Ltd. (ONC) and UNITED THERAPEUTICS Corp (UTHR). Click either name above to swap in a different company.

BeOne Medicines Ltd. is the larger business by last-quarter revenue ($1.5B vs $790.2M, roughly 1.9× UNITED THERAPEUTICS Corp). UNITED THERAPEUTICS Corp runs the higher net margin — 46.1% vs 4.4%, a 41.7% gap on every dollar of revenue. On growth, BeOne Medicines Ltd. posted the faster year-over-year revenue change (32.8% vs 7.4%). BeOne Medicines Ltd. produced more free cash flow last quarter ($379.8M vs $173.3M). Over the past eight quarters, BeOne Medicines Ltd.'s revenue compounded faster (41.2% CAGR vs 8.0%).

BeOne Medicines, formerly known as BeiGene, Ltd. is a multinational oncology company. It specializes in the development of drugs for cancer treatment.

United Therapeutics Corporation is an American biotechnology company that develops pharmaceuticals and technologies related to organ transplantation, including xenotransplantation. Many of the company's products are focused towards lung disease and organ manufacturing. United Therapeutics is co-headquartered in Silver Spring, Maryland and Research Triangle Park, North Carolina, with additional facilities in Magog and Bromont, Quebec; Melbourne and Jacksonville, Florida; Blacksburg, Virginia; ...

ONC vs UTHR — Head-to-Head

Bigger by revenue
ONC
ONC
1.9× larger
ONC
$1.5B
$790.2M
UTHR
Growing faster (revenue YoY)
ONC
ONC
+25.5% gap
ONC
32.8%
7.4%
UTHR
Higher net margin
UTHR
UTHR
41.7% more per $
UTHR
46.1%
4.4%
ONC
More free cash flow
ONC
ONC
$206.5M more FCF
ONC
$379.8M
$173.3M
UTHR
Faster 2-yr revenue CAGR
ONC
ONC
Annualised
ONC
41.2%
8.0%
UTHR

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ONC
ONC
UTHR
UTHR
Revenue
$1.5B
$790.2M
Net Profit
$66.5M
$364.3M
Gross Margin
90.5%
86.9%
Operating Margin
12.4%
45.1%
Net Margin
4.4%
46.1%
Revenue YoY
32.8%
7.4%
Net Profit YoY
143.8%
20.9%
EPS (diluted)
$0.05
$7.66

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ONC
ONC
UTHR
UTHR
Q4 25
$1.5B
$790.2M
Q3 25
$1.4B
$799.5M
Q2 25
$1.3B
$798.6M
Q1 25
$1.1B
$794.4M
Q4 24
$1.1B
$735.9M
Q3 24
$1.0B
$748.9M
Q2 24
$929.2M
$714.9M
Q1 24
$751.7M
$677.7M
Net Profit
ONC
ONC
UTHR
UTHR
Q4 25
$66.5M
$364.3M
Q3 25
$124.8M
$338.7M
Q2 25
$94.3M
$309.5M
Q1 25
$1.3M
$322.2M
Q4 24
$-151.9M
$301.3M
Q3 24
$-121.3M
$309.1M
Q2 24
$-120.4M
$278.1M
Q1 24
$-251.2M
$306.6M
Gross Margin
ONC
ONC
UTHR
UTHR
Q4 25
90.5%
86.9%
Q3 25
86.1%
87.4%
Q2 25
87.5%
89.0%
Q1 25
85.2%
88.4%
Q4 24
85.8%
89.7%
Q3 24
83.0%
88.9%
Q2 24
85.1%
89.1%
Q1 24
83.4%
89.2%
Operating Margin
ONC
ONC
UTHR
UTHR
Q4 25
12.4%
45.1%
Q3 25
11.5%
48.6%
Q2 25
6.7%
45.6%
Q1 25
1.0%
48.2%
Q4 24
-7.0%
48.6%
Q3 24
-12.0%
45.8%
Q2 24
-11.5%
44.7%
Q1 24
-34.8%
52.6%
Net Margin
ONC
ONC
UTHR
UTHR
Q4 25
4.4%
46.1%
Q3 25
8.8%
42.4%
Q2 25
7.2%
38.8%
Q1 25
0.1%
40.6%
Q4 24
-13.5%
40.9%
Q3 24
-12.1%
41.3%
Q2 24
-13.0%
38.9%
Q1 24
-33.4%
45.2%
EPS (diluted)
ONC
ONC
UTHR
UTHR
Q4 25
$0.05
$7.66
Q3 25
$0.08
$7.16
Q2 25
$0.06
$6.41
Q1 25
$0.00
$6.63
Q4 24
$-0.10
$6.23
Q3 24
$-0.09
$6.39
Q2 24
$-0.09
$5.85
Q1 24
$-0.19
$6.17

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ONC
ONC
UTHR
UTHR
Cash + ST InvestmentsLiquidity on hand
$4.5B
$2.9B
Total DebtLower is stronger
$836.4M
Stockholders' EquityBook value
$4.4B
$7.1B
Total Assets
$8.2B
$7.9B
Debt / EquityLower = less leverage
0.19×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ONC
ONC
UTHR
UTHR
Q4 25
$4.5B
$2.9B
Q3 25
$4.0B
$2.8B
Q2 25
$2.8B
$3.0B
Q1 25
$2.5B
$3.3B
Q4 24
$2.6B
$3.3B
Q3 24
$2.7B
$3.3B
Q2 24
$2.6B
$3.0B
Q1 24
$2.8B
$2.7B
Total Debt
ONC
ONC
UTHR
UTHR
Q4 25
$836.4M
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Stockholders' Equity
ONC
ONC
UTHR
UTHR
Q4 25
$4.4B
$7.1B
Q3 25
$4.1B
$6.6B
Q2 25
$3.8B
$7.2B
Q1 25
$3.5B
$6.8B
Q4 24
$3.3B
$6.4B
Q3 24
$3.4B
$6.1B
Q2 24
$3.4B
$5.7B
Q1 24
$3.4B
$5.3B
Total Assets
ONC
ONC
UTHR
UTHR
Q4 25
$8.2B
$7.9B
Q3 25
$7.6B
$7.4B
Q2 25
$6.3B
$7.9B
Q1 25
$5.8B
$7.7B
Q4 24
$5.9B
$7.4B
Q3 24
$5.8B
$7.1B
Q2 24
$5.7B
$6.7B
Q1 24
$5.7B
$6.5B
Debt / Equity
ONC
ONC
UTHR
UTHR
Q4 25
0.19×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ONC
ONC
UTHR
UTHR
Operating Cash FlowLast quarter
$417.3M
$346.2M
Free Cash FlowOCF − Capex
$379.8M
$173.3M
FCF MarginFCF / Revenue
25.4%
21.9%
Capex IntensityCapex / Revenue
2.5%
21.9%
Cash ConversionOCF / Net Profit
6.28×
0.95×
TTM Free Cash FlowTrailing 4 quarters
$941.7M
$1.0B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ONC
ONC
UTHR
UTHR
Q4 25
$417.3M
$346.2M
Q3 25
$402.6M
$562.1M
Q2 25
$263.6M
$191.7M
Q1 25
$44.1M
$461.2M
Q4 24
$75.2M
$341.2M
Q3 24
$188.4M
$377.2M
Q2 24
$-95.6M
$232.2M
Q1 24
$-308.6M
$376.5M
Free Cash Flow
ONC
ONC
UTHR
UTHR
Q4 25
$379.8M
$173.3M
Q3 25
$354.5M
$351.6M
Q2 25
$219.8M
$129.5M
Q1 25
$-12.3M
$386.3M
Q4 24
$-17.3M
$254.5M
Q3 24
$54.7M
$300.7M
Q2 24
$-205.5M
$187.1M
Q1 24
$-465.1M
$338.3M
FCF Margin
ONC
ONC
UTHR
UTHR
Q4 25
25.4%
21.9%
Q3 25
25.1%
44.0%
Q2 25
16.7%
16.2%
Q1 25
-1.1%
48.6%
Q4 24
-1.5%
34.6%
Q3 24
5.5%
40.2%
Q2 24
-22.1%
26.2%
Q1 24
-61.9%
49.9%
Capex Intensity
ONC
ONC
UTHR
UTHR
Q4 25
2.5%
21.9%
Q3 25
3.4%
26.3%
Q2 25
3.3%
7.8%
Q1 25
5.0%
9.4%
Q4 24
8.2%
11.8%
Q3 24
13.3%
10.2%
Q2 24
11.8%
6.3%
Q1 24
20.8%
5.6%
Cash Conversion
ONC
ONC
UTHR
UTHR
Q4 25
6.28×
0.95×
Q3 25
3.22×
1.66×
Q2 25
2.79×
0.62×
Q1 25
34.71×
1.43×
Q4 24
1.13×
Q3 24
1.22×
Q2 24
0.83×
Q1 24
1.23×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ONC
ONC

Segment breakdown not available.

UTHR
UTHR

Tyvaso DPI$338.6M43%
Remodulin$128.0M16%
Nebulized Tyvaso$125.7M16%
Orenitram$121.2M15%
Unituxin$62.3M8%
Adcirca$7.8M1%
Other$6.6M1%

Related Comparisons