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Side-by-side financial comparison of Alkermes plc. (ALKS) and PROSPERITY BANCSHARES INC (PB). Click either name above to swap in a different company.

Alkermes plc. is the larger business by last-quarter revenue ($384.5M vs $367.6M, roughly 1.0× PROSPERITY BANCSHARES INC). PROSPERITY BANCSHARES INC runs the higher net margin — 31.6% vs 12.8%, a 18.8% gap on every dollar of revenue. Over the past eight quarters, PROSPERITY BANCSHARES INC's revenue compounded faster (19.2% CAGR vs 4.8%).

Alkermes plc is a fully-integrated biopharmaceutical company that focuses on developing medicines for psychiatric and neurological disorders. The company was founded in 1987 by Michael Wall. In September 2011 Alkermes, Inc. merged with Elan Drug Technologies (EDT), the former drug formulation and manufacturing division of Élan Corporation, plc. The company is headquartered in Dublin, and has an R&D center in Waltham, Massachusetts, and a manufacturing facility in Wilmington, Ohio.

Prosperity Bancshares, Inc. is a bank holding company headquartered in Houston, Texas with operations in Texas and central Oklahoma. As of December 31, 2019, the company operated 285 branches: 65 in the Houston area, including The Woodlands, Texas; 30 in South Texas, including Corpus Christi, Texas and Victoria, Texas; 75 in the Dallas–Fort Worth metroplex; 22 in East Texas; 29 in Central Texas, including Austin, Texas and San Antonio; 34 in West Texas, including Lubbock, Texas, Midland–Odess...

ALKS vs PB — Head-to-Head

Bigger by revenue
ALKS
ALKS
1.0× larger
ALKS
$384.5M
$367.6M
PB
Higher net margin
PB
PB
18.8% more per $
PB
31.6%
12.8%
ALKS
Faster 2-yr revenue CAGR
PB
PB
Annualised
PB
19.2%
4.8%
ALKS

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
ALKS
ALKS
PB
PB
Revenue
$384.5M
$367.6M
Net Profit
$49.3M
$116.3M
Gross Margin
88.0%
Operating Margin
15.1%
Net Margin
12.8%
31.6%
Revenue YoY
-10.6%
Net Profit YoY
-66.3%
-10.7%
EPS (diluted)
$0.29
$1.16

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ALKS
ALKS
PB
PB
Q1 26
$367.6M
Q4 25
$384.5M
$275.0M
Q3 25
$394.2M
$273.4M
Q2 25
$390.7M
$267.7M
Q1 25
$306.5M
$265.4M
Q4 24
$430.0M
$267.8M
Q3 24
$378.1M
$261.7M
Q2 24
$399.1M
$258.8M
Net Profit
ALKS
ALKS
PB
PB
Q1 26
$116.3M
Q4 25
$49.3M
$139.9M
Q3 25
$82.8M
$137.6M
Q2 25
$87.1M
$135.2M
Q1 25
$22.5M
$130.2M
Q4 24
$146.5M
$130.1M
Q3 24
$92.4M
$127.3M
Q2 24
$91.4M
$111.6M
Gross Margin
ALKS
ALKS
PB
PB
Q1 26
Q4 25
88.0%
Q3 25
86.9%
Q2 25
87.3%
Q1 25
83.9%
Q4 24
85.6%
Q3 24
83.3%
Q2 24
84.6%
Operating Margin
ALKS
ALKS
PB
PB
Q1 26
Q4 25
15.1%
65.1%
Q3 25
22.6%
64.4%
Q2 25
23.8%
64.3%
Q1 25
4.5%
62.7%
Q4 24
37.8%
62.0%
Q3 24
27.7%
62.1%
Q2 24
27.5%
55.2%
Net Margin
ALKS
ALKS
PB
PB
Q1 26
31.6%
Q4 25
12.8%
50.9%
Q3 25
21.0%
50.3%
Q2 25
22.3%
50.5%
Q1 25
7.3%
49.1%
Q4 24
34.1%
48.6%
Q3 24
24.4%
48.6%
Q2 24
22.9%
43.1%
EPS (diluted)
ALKS
ALKS
PB
PB
Q1 26
$1.16
Q4 25
$0.29
$1.48
Q3 25
$0.49
$1.45
Q2 25
$0.52
$1.42
Q1 25
$0.13
$1.37
Q4 24
$0.88
$1.36
Q3 24
$0.55
$1.34
Q2 24
$0.53
$1.17

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ALKS
ALKS
PB
PB
Cash + ST InvestmentsLiquidity on hand
$388.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.8B
$8.2B
Total Assets
$2.5B
$43.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ALKS
ALKS
PB
PB
Q1 26
Q4 25
$388.6M
Q3 25
$616.4M
Q2 25
$521.2M
Q1 25
$399.8M
Q4 24
$291.1M
Q3 24
$396.3M
Q2 24
$535.1M
Stockholders' Equity
ALKS
ALKS
PB
PB
Q1 26
$8.2B
Q4 25
$1.8B
$7.6B
Q3 25
$1.7B
$7.7B
Q2 25
$1.6B
$7.6B
Q1 25
$1.5B
$7.5B
Q4 24
$1.5B
$7.4B
Q3 24
$1.3B
$7.4B
Q2 24
$1.3B
$7.3B
Total Assets
ALKS
ALKS
PB
PB
Q1 26
$43.6B
Q4 25
$2.5B
$38.5B
Q3 25
$2.3B
$38.3B
Q2 25
$2.3B
$38.4B
Q1 25
$2.1B
$38.8B
Q4 24
$2.1B
$39.6B
Q3 24
$2.2B
$40.1B
Q2 24
$2.2B
$39.8B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ALKS
ALKS
PB
PB
Operating Cash FlowLast quarter
$170.1M
Free Cash FlowOCF − Capex
$170.0M
FCF MarginFCF / Revenue
44.2%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
3.45×
TTM Free Cash FlowTrailing 4 quarters
$480.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ALKS
ALKS
PB
PB
Q1 26
Q4 25
$170.1M
$78.3M
Q3 25
$101.7M
$194.8M
Q2 25
$150.2M
$98.2M
Q1 25
$98.8M
$178.2M
Q4 24
$190.4M
$-205.8M
Q3 24
$81.6M
$274.6M
Q2 24
$146.0M
$216.5M
Free Cash Flow
ALKS
ALKS
PB
PB
Q1 26
Q4 25
$170.0M
$68.5M
Q3 25
$84.4M
$185.7M
Q2 25
$137.2M
$91.8M
Q1 25
$88.7M
$171.1M
Q4 24
$180.6M
$-210.7M
Q3 24
$73.3M
$270.2M
Q2 24
$138.9M
$211.8M
FCF Margin
ALKS
ALKS
PB
PB
Q1 26
Q4 25
44.2%
24.9%
Q3 25
21.4%
67.9%
Q2 25
35.1%
34.3%
Q1 25
28.9%
64.5%
Q4 24
42.0%
-78.7%
Q3 24
19.4%
103.3%
Q2 24
34.8%
81.8%
Capex Intensity
ALKS
ALKS
PB
PB
Q1 26
Q4 25
0.0%
3.6%
Q3 25
4.4%
3.3%
Q2 25
3.3%
2.4%
Q1 25
3.3%
2.7%
Q4 24
2.3%
1.8%
Q3 24
2.2%
1.7%
Q2 24
1.8%
1.8%
Cash Conversion
ALKS
ALKS
PB
PB
Q1 26
Q4 25
3.45×
0.56×
Q3 25
1.23×
1.42×
Q2 25
1.72×
0.73×
Q1 25
4.40×
1.37×
Q4 24
1.30×
-1.58×
Q3 24
0.88×
2.16×
Q2 24
1.60×
1.94×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ALKS
ALKS

Vivitrol$124.1M32%
Aristada And Aristada Initio$97.2M25%
LYBALVI$94.1M24%
Royalty$65.7M17%
Manufacturing Revenue$3.3M1%

PB
PB

Net Interest Income$321.1M87%
Noninterest Income$46.5M13%

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