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Side-by-side financial comparison of Amgen (AMGN) and Hewlett Packard Enterprise (HPE). Click either name above to swap in a different company.

Amgen is the larger business by last-quarter revenue ($9.9B vs $9.7B, roughly 1.0× Hewlett Packard Enterprise). Amgen runs the higher net margin — 13.5% vs 1.8%, a 11.7% gap on every dollar of revenue. On growth, Hewlett Packard Enterprise posted the faster year-over-year revenue change (14.4% vs 8.6%). Hewlett Packard Enterprise produced more free cash flow last quarter ($1.8B vs $961.0M). Over the past eight quarters, Hewlett Packard Enterprise's revenue compounded faster (19.7% CAGR vs 15.1%).

Amgen Inc. is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California. The company is ranked 18th on the list of largest biomedical companies by revenue. The name "AMGen" is a portmanteau of the company's original name, Applied Molecular Genetics.

The Hewlett Packard Enterprise Company (HPE) is an American multinational information technology company based in Spring, Texas. It is a business-focused organization which works in servers, storage, networking, containerization software and consulting and support. HPE was ranked No. 107 in the 2018 Fortune 500 list of the largest United States corporations by total revenue.

AMGN vs HPE — Head-to-Head

Bigger by revenue
AMGN
AMGN
1.0× larger
AMGN
$9.9B
$9.7B
HPE
Growing faster (revenue YoY)
HPE
HPE
+5.9% gap
HPE
14.4%
8.6%
AMGN
Higher net margin
AMGN
AMGN
11.7% more per $
AMGN
13.5%
1.8%
HPE
More free cash flow
HPE
HPE
$863.0M more FCF
HPE
$1.8B
$961.0M
AMGN
Faster 2-yr revenue CAGR
HPE
HPE
Annualised
HPE
19.7%
15.1%
AMGN

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AMGN
AMGN
HPE
HPE
Revenue
$9.9B
$9.7B
Net Profit
$1.3B
$175.0M
Gross Margin
69.8%
Operating Margin
27.6%
-0.1%
Net Margin
13.5%
1.8%
Revenue YoY
8.6%
14.4%
Net Profit YoY
112.6%
-87.2%
EPS (diluted)
$2.45
$0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AMGN
AMGN
HPE
HPE
Q4 25
$9.9B
$9.7B
Q3 25
$9.6B
$9.1B
Q2 25
$9.2B
$7.6B
Q1 25
$8.1B
$7.9B
Q4 24
$9.1B
$8.5B
Q3 24
$8.5B
$7.7B
Q2 24
$8.4B
$7.2B
Q1 24
$7.4B
$6.8B
Net Profit
AMGN
AMGN
HPE
HPE
Q4 25
$1.3B
$175.0M
Q3 25
$3.2B
$305.0M
Q2 25
$1.4B
$-1.1B
Q1 25
$1.7B
$627.0M
Q4 24
$627.0M
$1.4B
Q3 24
$2.8B
$512.0M
Q2 24
$746.0M
$314.0M
Q1 24
$-113.0M
$387.0M
Gross Margin
AMGN
AMGN
HPE
HPE
Q4 25
69.8%
Q3 25
67.8%
Q2 25
67.2%
Q1 25
63.6%
Q4 24
65.7%
Q3 24
61.1%
Q2 24
61.4%
Q1 24
57.0%
Operating Margin
AMGN
AMGN
HPE
HPE
Q4 25
27.6%
-0.1%
Q3 25
26.4%
2.7%
Q2 25
28.9%
-14.5%
Q1 25
14.5%
5.5%
Q4 24
25.4%
8.2%
Q3 24
24.1%
7.1%
Q2 24
22.8%
5.9%
Q1 24
13.3%
7.8%
Net Margin
AMGN
AMGN
HPE
HPE
Q4 25
13.5%
1.8%
Q3 25
33.7%
3.3%
Q2 25
15.6%
-13.8%
Q1 25
21.2%
8.0%
Q4 24
6.9%
16.2%
Q3 24
33.3%
6.6%
Q2 24
8.9%
4.4%
Q1 24
-1.5%
5.7%
EPS (diluted)
AMGN
AMGN
HPE
HPE
Q4 25
$2.45
$0.13
Q3 25
$5.93
$0.21
Q2 25
$2.65
$-0.82
Q1 25
$3.20
$0.44
Q4 24
$1.17
$1.02
Q3 24
$5.22
$0.38
Q2 24
$1.38
$0.24
Q1 24
$-0.21
$0.29

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AMGN
AMGN
HPE
HPE
Cash + ST InvestmentsLiquidity on hand
$9.1B
$5.8B
Total DebtLower is stronger
$54.6B
$17.8B
Stockholders' EquityBook value
$8.7B
$24.7B
Total Assets
$90.6B
$75.9B
Debt / EquityLower = less leverage
6.31×
0.72×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AMGN
AMGN
HPE
HPE
Q4 25
$9.1B
$5.8B
Q3 25
$9.4B
$4.6B
Q2 25
$8.0B
$11.7B
Q1 25
$8.8B
$13.4B
Q4 24
$12.0B
$14.8B
Q3 24
$9.0B
$3.6B
Q2 24
$9.3B
$2.7B
Q1 24
$9.7B
$3.8B
Total Debt
AMGN
AMGN
HPE
HPE
Q4 25
$54.6B
$17.8B
Q3 25
$54.6B
$16.9B
Q2 25
$56.2B
$12.4B
Q1 25
$57.4B
$13.3B
Q4 24
$60.1B
$13.5B
Q3 24
$60.4B
$7.9B
Q2 24
$62.6B
$7.5B
Q1 24
$64.0B
$7.8B
Stockholders' Equity
AMGN
AMGN
HPE
HPE
Q4 25
$8.7B
$24.7B
Q3 25
$9.6B
$24.4B
Q2 25
$7.4B
$23.9B
Q1 25
$6.2B
$25.2B
Q4 24
$5.9B
$24.8B
Q3 24
$7.5B
$22.1B
Q2 24
$5.9B
$21.7B
Q1 24
$5.0B
$21.4B
Total Assets
AMGN
AMGN
HPE
HPE
Q4 25
$90.6B
$75.9B
Q3 25
$90.1B
$77.3B
Q2 25
$87.9B
$67.9B
Q1 25
$89.4B
$70.3B
Q4 24
$91.8B
$71.3B
Q3 24
$90.9B
$60.9B
Q2 24
$90.9B
$59.7B
Q1 24
$93.0B
$58.6B
Debt / Equity
AMGN
AMGN
HPE
HPE
Q4 25
6.31×
0.72×
Q3 25
5.67×
0.69×
Q2 25
7.57×
0.52×
Q1 25
9.24×
0.53×
Q4 24
10.23×
0.54×
Q3 24
8.02×
0.36×
Q2 24
10.57×
0.35×
Q1 24
12.75×
0.37×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AMGN
AMGN
HPE
HPE
Operating Cash FlowLast quarter
$1.6B
$2.5B
Free Cash FlowOCF − Capex
$961.0M
$1.8B
FCF MarginFCF / Revenue
9.7%
18.8%
Capex IntensityCapex / Revenue
6.5%
6.6%
Cash ConversionOCF / Net Profit
1.20×
14.09×
TTM Free Cash FlowTrailing 4 quarters
$8.1B
$627.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AMGN
AMGN
HPE
HPE
Q4 25
$1.6B
$2.5B
Q3 25
$4.7B
$1.3B
Q2 25
$2.3B
$-461.0M
Q1 25
$1.4B
$-390.0M
Q4 24
$4.8B
$2.0B
Q3 24
$3.6B
$1.2B
Q2 24
$2.5B
$1.1B
Q1 24
$689.0M
$64.0M
Free Cash Flow
AMGN
AMGN
HPE
HPE
Q4 25
$961.0M
$1.8B
Q3 25
$4.2B
$729.0M
Q2 25
$1.9B
$-1.0B
Q1 25
$980.0M
$-918.0M
Q4 24
$4.4B
$1.4B
Q3 24
$3.3B
$611.0M
Q2 24
$2.2B
$533.0M
Q1 24
$459.0M
$-592.0M
FCF Margin
AMGN
AMGN
HPE
HPE
Q4 25
9.7%
18.8%
Q3 25
44.4%
8.0%
Q2 25
20.8%
-13.2%
Q1 25
12.0%
-11.7%
Q4 24
48.4%
16.8%
Q3 24
39.0%
7.9%
Q2 24
26.5%
7.4%
Q1 24
6.2%
-8.8%
Capex Intensity
AMGN
AMGN
HPE
HPE
Q4 25
6.5%
6.6%
Q3 25
4.6%
6.3%
Q2 25
4.0%
7.2%
Q1 25
5.0%
6.7%
Q4 24
4.1%
7.2%
Q3 24
3.0%
7.0%
Q2 24
2.8%
7.8%
Q1 24
3.1%
9.7%
Cash Conversion
AMGN
AMGN
HPE
HPE
Q4 25
1.20×
14.09×
Q3 25
1.46×
4.28×
Q2 25
1.59×
Q1 25
0.80×
-0.62×
Q4 24
7.61×
1.49×
Q3 24
1.26×
2.25×
Q2 24
3.30×
3.48×
Q1 24
0.17×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AMGN
AMGN

Products$9.4B95%
Xgeva$291.0M3%
Vectibix$163.0M2%
Aranesp$115.0M1%

HPE
HPE

Products$6.2B64%
Services$3.3B34%
Other$199.0M2%

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