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Side-by-side financial comparison of Amgen (AMGN) and Humana (HUM), based on the latest 10-Q / 10-K filings. Click either name above to swap in a different company.

Humana is the larger business by last-quarter revenue ($32.5B vs $9.9B, roughly 3.3× Amgen). Amgen runs the higher net margin — 13.5% vs -2.4%, a 16.0% gap on every dollar of revenue. On growth, Humana posted the faster year-over-year revenue change (11.3% vs 8.6%). Amgen produced more free cash flow last quarter ($961.0M vs $-1.9B). Over the past eight quarters, Amgen's revenue compounded faster (15.1% CAGR vs 4.8%).

Amgen Inc. is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California. The company is ranked 18th on the list of largest biomedical companies by revenue. The name "AMGen" is a portmanteau of the company's original name, Applied Molecular Genetics.

Humana Inc. is an American for-profit health insurance company based in Louisville, Kentucky. In 2024, the company ranked 92 on the Fortune 500 list, which made it the highest ranked company based in Kentucky. It is the fourth largest health insurance provider in the U.S.

AMGN vs HUM — Head-to-Head

Bigger by revenue
HUM
HUM
3.3× larger
HUM
$32.5B
$9.9B
AMGN
Growing faster (revenue YoY)
HUM
HUM
+2.7% gap
HUM
11.3%
8.6%
AMGN
Higher net margin
AMGN
AMGN
16.0% more per $
AMGN
13.5%
-2.4%
HUM
More free cash flow
AMGN
AMGN
$2.8B more FCF
AMGN
$961.0M
$-1.9B
HUM
Faster 2-yr revenue CAGR
AMGN
AMGN
Annualised
AMGN
15.1%
4.8%
HUM

Income Statement — Q4 2025 vs Q4 2025

Metric
AMGN
AMGN
HUM
HUM
Revenue
$9.9B
$32.5B
Net Profit
$1.3B
$-796.0M
Gross Margin
69.8%
Operating Margin
27.6%
-2.5%
Net Margin
13.5%
-2.4%
Revenue YoY
8.6%
11.3%
Net Profit YoY
112.6%
-14.9%
EPS (diluted)
$2.45
$-6.59

Green = leading value per metric. Periods may differ when fiscal calendars don't align — see 8-quarter trend below.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history — bar widths are scaled to the larger of the two companies so you can eyeball the size gap and growth trajectory without doing math. Quarters aligned by calendar period (report date) so offset fiscal years line up.

Revenue
AMGN
AMGN
HUM
HUM
Q4 25
$9.9B
$32.5B
Q3 25
$9.6B
$32.6B
Q2 25
$9.2B
$32.4B
Q1 25
$8.1B
$32.1B
Q4 24
$9.1B
$29.2B
Q3 24
$8.5B
$29.4B
Q2 24
$8.4B
$29.5B
Q1 24
$7.4B
$29.6B
Net Profit
AMGN
AMGN
HUM
HUM
Q4 25
$1.3B
$-796.0M
Q3 25
$3.2B
$195.0M
Q2 25
$1.4B
$545.0M
Q1 25
$1.7B
$1.2B
Q4 24
$627.0M
$-693.0M
Q3 24
$2.8B
$480.0M
Q2 24
$746.0M
$679.0M
Q1 24
$-113.0M
$741.0M
Gross Margin
AMGN
AMGN
HUM
HUM
Q4 25
69.8%
Q3 25
67.8%
Q2 25
67.2%
Q1 25
63.6%
Q4 24
65.7%
Q3 24
61.1%
Q2 24
61.4%
Q1 24
57.0%
Operating Margin
AMGN
AMGN
HUM
HUM
Q4 25
27.6%
-2.5%
Q3 25
26.4%
1.2%
Q2 25
28.9%
3.4%
Q1 25
14.5%
6.3%
Q4 24
25.4%
-1.9%
Q3 24
24.1%
2.5%
Q2 24
22.8%
3.9%
Q1 24
13.3%
4.2%
Net Margin
AMGN
AMGN
HUM
HUM
Q4 25
13.5%
-2.4%
Q3 25
33.7%
0.6%
Q2 25
15.6%
1.7%
Q1 25
21.2%
3.9%
Q4 24
6.9%
-2.4%
Q3 24
33.3%
1.6%
Q2 24
8.9%
2.3%
Q1 24
-1.5%
2.5%
EPS (diluted)
AMGN
AMGN
HUM
HUM
Q4 25
$2.45
$-6.59
Q3 25
$5.93
$1.62
Q2 25
$2.65
$4.51
Q1 25
$3.20
$10.30
Q4 24
$1.17
$-5.73
Q3 24
$5.22
$3.98
Q2 24
$1.38
$5.62
Q1 24
$-0.21
$6.11

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest filing — the kind of financial-strength check premium terminals charge for.

Metric
AMGN
AMGN
HUM
HUM
Cash + ST InvestmentsLiquidity on hand
$9.1B
$19.9B
Total DebtLower is stronger
$54.6B
Stockholders' EquityBook value
$8.7B
$17.7B
Total Assets
$90.6B
$48.9B
Debt / EquityLower = less leverage
6.31×

8-quarter trend — quarters aligned by calendar period so offset fiscal years match up.

Cash + ST Investments
AMGN
AMGN
HUM
HUM
Q4 25
$9.1B
$19.9B
Q3 25
$9.4B
$22.1B
Q2 25
$8.0B
$21.7B
Q1 25
$8.8B
$22.1B
Q4 24
$12.0B
$20.4B
Q3 24
$9.0B
$24.1B
Q2 24
$9.3B
$22.9B
Q1 24
$9.7B
$22.6B
Total Debt
AMGN
AMGN
HUM
HUM
Q4 25
$54.6B
Q3 25
$54.6B
Q2 25
$56.2B
Q1 25
$57.4B
Q4 24
$60.1B
Q3 24
$60.4B
Q2 24
$62.6B
Q1 24
$64.0B
Stockholders' Equity
AMGN
AMGN
HUM
HUM
Q4 25
$8.7B
$17.7B
Q3 25
$9.6B
$18.5B
Q2 25
$7.4B
$18.2B
Q1 25
$6.2B
$17.8B
Q4 24
$5.9B
$16.4B
Q3 24
$7.5B
$17.6B
Q2 24
$5.9B
$16.7B
Q1 24
$5.0B
$16.1B
Total Assets
AMGN
AMGN
HUM
HUM
Q4 25
$90.6B
$48.9B
Q3 25
$90.1B
$49.7B
Q2 25
$87.9B
$50.4B
Q1 25
$89.4B
$50.9B
Q4 24
$91.8B
$46.5B
Q3 24
$90.9B
$50.0B
Q2 24
$90.9B
$50.1B
Q1 24
$93.0B
$50.1B
Debt / Equity
AMGN
AMGN
HUM
HUM
Q4 25
6.31×
Q3 25
5.67×
Q2 25
7.57×
Q1 25
9.24×
Q4 24
10.23×
Q3 24
8.02×
Q2 24
10.57×
Q1 24
12.75×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Net income can be massaged; cash flow is harder to fake.

Metric
AMGN
AMGN
HUM
HUM
Operating Cash FlowLast quarter
$1.6B
$-1.7B
Free Cash FlowOCF − Capex
$961.0M
$-1.9B
FCF MarginFCF / Revenue
9.7%
-5.7%
Capex IntensityCapex / Revenue; lower = less reinvestment burden
6.5%
0.6%
Cash ConversionOCF / Net Profit; >1× = earnings back up with cash
1.20×
TTM Free Cash FlowTrailing 4 quarters
$8.1B
$375.0M

8-quarter trend — quarters aligned by calendar period so offset fiscal years match up.

Operating Cash Flow
AMGN
AMGN
HUM
HUM
Q4 25
$1.6B
$-1.7B
Q3 25
$4.7B
$971.0M
Q2 25
$2.3B
$1.3B
Q1 25
$1.4B
$331.0M
Q4 24
$4.8B
$-528.0M
Q3 24
$3.6B
$1.9B
Q2 24
$2.5B
$1.2B
Q1 24
$689.0M
$423.0M
Free Cash Flow
AMGN
AMGN
HUM
HUM
Q4 25
$961.0M
$-1.9B
Q3 25
$4.2B
$836.0M
Q2 25
$1.9B
$1.2B
Q1 25
$980.0M
$236.0M
Q4 24
$4.4B
$-682.0M
Q3 24
$3.3B
$1.7B
Q2 24
$2.2B
$1.1B
Q1 24
$459.0M
$246.0M
FCF Margin
AMGN
AMGN
HUM
HUM
Q4 25
9.7%
-5.7%
Q3 25
44.4%
2.6%
Q2 25
20.8%
3.6%
Q1 25
12.0%
0.7%
Q4 24
48.4%
-2.3%
Q3 24
39.0%
5.9%
Q2 24
26.5%
3.7%
Q1 24
6.2%
0.8%
Capex Intensity
AMGN
AMGN
HUM
HUM
Q4 25
6.5%
0.6%
Q3 25
4.6%
0.4%
Q2 25
4.0%
0.4%
Q1 25
5.0%
0.3%
Q4 24
4.1%
0.5%
Q3 24
3.0%
0.4%
Q2 24
2.8%
0.4%
Q1 24
3.1%
0.6%
Cash Conversion
AMGN
AMGN
HUM
HUM
Q4 25
1.20×
Q3 25
1.46×
4.98×
Q2 25
1.59×
2.33×
Q1 25
0.80×
0.27×
Q4 24
7.61×
Q3 24
1.26×
3.87×
Q2 24
3.30×
1.79×
Q1 24
0.57×

Financial Flow Comparison

Sankey diagram of revenue → gross profit → operating profit → net profit for each company. Charts shown full-width and stacked so both segment hierarchies are readable side-by-side on desktop and mobile.

Revenue Breakdown by Segment

AMGN
AMGN

Products$9.4B95%
Xgeva$291.0M3%
Vectibix$163.0M2%
Aranesp$115.0M1%

HUM
HUM

Insurance Segment$31.3B96%
Other$880.0M3%
Services$292.0M1%

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