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Side-by-side financial comparison of AMERISAFE INC (AMSF) and ARDELYX, INC. (ARDX). Click either name above to swap in a different company.

ARDELYX, INC. is the larger business by last-quarter revenue ($94.5M vs $80.1M, roughly 1.2× AMERISAFE INC). AMERISAFE INC runs the higher net margin — 10.2% vs -39.8%, a 50.0% gap on every dollar of revenue. On growth, ARDELYX, INC. posted the faster year-over-year revenue change (27.5% vs 10.3%). Over the past eight quarters, ARDELYX, INC.'s revenue compounded faster (13.6% CAGR vs 2.8%).

AMERISAFE Inc. is a specialty insurance provider that focuses exclusively on workers' compensation coverage for small and mid-sized businesses in high-hazard industries including construction, logging, trucking, and manufacturing. It operates across 49 U.S. states, offering tailored insurance policies paired with targeted risk management support for clients.

Ardelyx, Inc. is a commercial-stage biopharmaceutical firm developing and commercializing innovative therapies for gastrointestinal, cardiorenal and metabolic diseases with high unmet medical needs. Its lead product is approved in the US for irritable bowel syndrome with constipation, and it holds a robust pipeline of early and late-stage drug candidates.

AMSF vs ARDX — Head-to-Head

Bigger by revenue
ARDX
ARDX
1.2× larger
ARDX
$94.5M
$80.1M
AMSF
Growing faster (revenue YoY)
ARDX
ARDX
+17.1% gap
ARDX
27.5%
10.3%
AMSF
Higher net margin
AMSF
AMSF
50.0% more per $
AMSF
10.2%
-39.8%
ARDX
Faster 2-yr revenue CAGR
ARDX
ARDX
Annualised
ARDX
13.6%
2.8%
AMSF

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
AMSF
AMSF
ARDX
ARDX
Revenue
$80.1M
$94.5M
Net Profit
$8.1M
$-37.6M
Gross Margin
Operating Margin
Net Margin
10.2%
-39.8%
Revenue YoY
10.3%
27.5%
Net Profit YoY
-9.0%
EPS (diluted)
$0.43
$-0.15

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AMSF
AMSF
ARDX
ARDX
Q1 26
$80.1M
$94.5M
Q4 25
$81.6M
$125.2M
Q3 25
$82.0M
$110.3M
Q2 25
$81.1M
$97.7M
Q1 25
$72.6M
$74.1M
Q4 24
$74.0M
$116.1M
Q3 24
$78.7M
$98.2M
Q2 24
$75.8M
$73.2M
Net Profit
AMSF
AMSF
ARDX
ARDX
Q1 26
$8.1M
$-37.6M
Q4 25
$10.4M
$-407.0K
Q3 25
$13.8M
$-969.0K
Q2 25
$14.0M
$-19.1M
Q1 25
$8.9M
$-41.1M
Q4 24
$13.2M
$4.6M
Q3 24
$14.3M
$-809.0K
Q2 24
$11.0M
$-16.5M
Gross Margin
AMSF
AMSF
ARDX
ARDX
Q1 26
Q4 25
91.3%
Q3 25
96.4%
Q2 25
87.3%
Q1 25
83.4%
Q4 24
84.3%
Q3 24
84.0%
Q2 24
87.1%
Operating Margin
AMSF
AMSF
ARDX
ARDX
Q1 26
Q4 25
15.6%
4.1%
Q3 25
21.3%
4.2%
Q2 25
21.5%
-14.7%
Q1 25
15.5%
-49.0%
Q4 24
22.7%
7.0%
Q3 24
22.6%
2.3%
Q2 24
18.1%
-18.6%
Net Margin
AMSF
AMSF
ARDX
ARDX
Q1 26
10.2%
-39.8%
Q4 25
12.8%
-0.3%
Q3 25
16.9%
-0.9%
Q2 25
17.2%
-19.5%
Q1 25
12.3%
-55.5%
Q4 24
17.8%
4.0%
Q3 24
18.2%
-0.8%
Q2 24
14.5%
-22.5%
EPS (diluted)
AMSF
AMSF
ARDX
ARDX
Q1 26
$0.43
$-0.15
Q4 25
$0.55
$-0.01
Q3 25
$0.72
$0.00
Q2 25
$0.73
$-0.08
Q1 25
$0.47
$-0.17
Q4 24
$0.69
$0.01
Q3 24
$0.75
$0.00
Q2 24
$0.57
$-0.07

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AMSF
AMSF
ARDX
ARDX
Cash + ST InvestmentsLiquidity on hand
$34.2M
$238.1M
Total DebtLower is stronger
$203.5M
Stockholders' EquityBook value
$246.6M
$148.6M
Total Assets
$504.5M
Debt / EquityLower = less leverage
1.37×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AMSF
AMSF
ARDX
ARDX
Q1 26
$34.2M
$238.1M
Q4 25
$61.9M
$68.0M
Q3 25
$54.7M
$42.7M
Q2 25
$48.5M
$90.0M
Q1 25
$44.8M
$30.8M
Q4 24
$44.1M
$64.9M
Q3 24
$63.7M
$47.4M
Q2 24
$30.6M
$41.9M
Total Debt
AMSF
AMSF
ARDX
ARDX
Q1 26
$203.5M
Q4 25
$202.8M
Q3 25
$202.1M
Q2 25
$201.4M
Q1 25
$151.3M
Q4 24
$150.9M
Q3 24
$100.7M
Q2 24
$100.2M
Stockholders' Equity
AMSF
AMSF
ARDX
ARDX
Q1 26
$246.6M
$148.6M
Q4 25
$251.6M
$166.9M
Q3 25
$274.8M
$154.3M
Q2 25
$265.6M
$139.5M
Q1 25
$260.8M
$145.7M
Q4 24
$257.3M
$173.3M
Q3 24
$314.4M
$158.3M
Q2 24
$301.0M
$147.0M
Total Assets
AMSF
AMSF
ARDX
ARDX
Q1 26
$504.5M
Q4 25
$1.1B
$501.6M
Q3 25
$1.2B
$486.2M
Q2 25
$1.2B
$466.8M
Q1 25
$1.2B
$410.2M
Q4 24
$1.2B
$435.8M
Q3 24
$1.3B
$367.9M
Q2 24
$1.2B
$343.5M
Debt / Equity
AMSF
AMSF
ARDX
ARDX
Q1 26
1.37×
Q4 25
1.21×
Q3 25
1.31×
Q2 25
1.44×
Q1 25
1.04×
Q4 24
0.87×
Q3 24
0.64×
Q2 24
0.68×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AMSF
AMSF

Segment breakdown not available.

ARDX
ARDX

IBSRELA$70.1M74%
XPHOZAH$23.3M25%
Non-cash royalty revenue related to the sale of future royalties$695.0K1%
Product supply revenue$354.0K0%

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