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Side-by-side financial comparison of Amesite Inc. (AMST) and VYNE Therapeutics Inc. (VYNE). Click either name above to swap in a different company.

Amesite Inc. is the larger business by last-quarter revenue ($108.0K vs $69.0K, roughly 1.6× VYNE Therapeutics Inc.). Amesite Inc. runs the higher net margin — -678.0% vs -8340.6%, a 7662.6% gap on every dollar of revenue. On growth, Amesite Inc. posted the faster year-over-year revenue change (746.8% vs -65.2%). Over the past eight quarters, VYNE Therapeutics Inc.'s revenue compounded faster (-22.2% CAGR vs -32.5%).

Amesite Inc is a US-based edtech firm that develops and delivers AI-powered cloud learning management systems and customized online learning solutions. Its core offerings cater to higher education institutions, corporate clients, and government organizations, enabling scalable, personalized upskilling, professional training, and academic course delivery across North America.

VYNE Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing innovative therapies for dermatological conditions. Its product pipeline targets both common and underserved skin disorders, with primary operations and market reach across the United States, partnering with healthcare providers and specialty pharmacy networks to serve patients.

AMST vs VYNE — Head-to-Head

Bigger by revenue
AMST
AMST
1.6× larger
AMST
$108.0K
$69.0K
VYNE
Growing faster (revenue YoY)
AMST
AMST
+811.9% gap
AMST
746.8%
-65.2%
VYNE
Higher net margin
AMST
AMST
7662.6% more per $
AMST
-678.0%
-8340.6%
VYNE
Faster 2-yr revenue CAGR
VYNE
VYNE
Annualised
VYNE
-22.2%
-32.5%
AMST

Income Statement — Q2 FY2026 vs Q2 FY2025

Metric
AMST
AMST
VYNE
VYNE
Revenue
$108.0K
$69.0K
Net Profit
$-732.5K
$-5.8M
Gross Margin
Operating Margin
-689.7%
-10930.4%
Net Margin
-678.0%
-8340.6%
Revenue YoY
746.8%
-65.2%
Net Profit YoY
34.7%
38.8%
EPS (diluted)
$-0.16
$-0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AMST
AMST
VYNE
VYNE
Q4 25
$108.0K
Q3 25
$94.3K
Q2 25
$55.8K
$69.0K
Q1 25
$202.0K
Q4 24
$84.0K
Q3 24
$121.0K
Q2 24
$198.0K
Q1 24
$98.0K
Net Profit
AMST
AMST
VYNE
VYNE
Q4 25
$-732.5K
Q3 25
$-642.3K
Q2 25
$-924.0K
$-5.8M
Q1 25
$-8.6M
Q4 24
$-12.0M
Q3 24
$-12.2M
Q2 24
$-9.4M
Q1 24
$-6.2M
Operating Margin
AMST
AMST
VYNE
VYNE
Q4 25
-689.7%
Q3 25
-702.2%
Q2 25
-1538.2%
-10930.4%
Q1 25
-4553.0%
Q4 24
-15202.4%
Q3 24
-10819.0%
Q2 24
-5250.5%
Q1 24
-7530.6%
Net Margin
AMST
AMST
VYNE
VYNE
Q4 25
-678.0%
Q3 25
-681.1%
Q2 25
-1657.1%
-8340.6%
Q1 25
-4262.9%
Q4 24
-14311.9%
Q3 24
-10047.1%
Q2 24
-4750.5%
Q1 24
-6376.5%
EPS (diluted)
AMST
AMST
VYNE
VYNE
Q4 25
$-0.16
Q3 25
$-0.14
Q2 25
$-0.13
$-0.13
Q1 25
$-0.20
Q4 24
$-0.27
Q3 24
$-0.29
Q2 24
$-0.22
Q1 24
$-0.15

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AMST
AMST
VYNE
VYNE
Cash + ST InvestmentsLiquidity on hand
$1.2M
$39.6M
Total DebtLower is stronger
$0
Stockholders' EquityBook value
$1.5M
$38.9M
Total Assets
$2.0M
$44.7M
Debt / EquityLower = less leverage
0.00×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AMST
AMST
VYNE
VYNE
Q4 25
$1.2M
Q3 25
$1.8M
Q2 25
$2.3M
$39.6M
Q1 25
$50.3M
Q4 24
$61.5M
Q3 24
$70.2M
Q2 24
$78.1M
Q1 24
$86.0M
Total Debt
AMST
AMST
VYNE
VYNE
Q4 25
Q3 25
Q2 25
$0
Q1 25
$0
Q4 24
$0
Q3 24
$0
Q2 24
$0
Q1 24
$0
Stockholders' Equity
AMST
AMST
VYNE
VYNE
Q4 25
$1.5M
Q3 25
$2.2M
Q2 25
$2.7M
$38.9M
Q1 25
$44.1M
Q4 24
$52.1M
Q3 24
$63.5M
Q2 24
$74.9M
Q1 24
$83.4M
Total Assets
AMST
AMST
VYNE
VYNE
Q4 25
$2.0M
Q3 25
$2.6M
Q2 25
$3.1M
$44.7M
Q1 25
$56.4M
Q4 24
$66.9M
Q3 24
$76.2M
Q2 24
$86.6M
Q1 24
$91.7M
Debt / Equity
AMST
AMST
VYNE
VYNE
Q4 25
Q3 25
Q2 25
0.00×
Q1 25
0.00×
Q4 24
0.00×
Q3 24
0.00×
Q2 24
0.00×
Q1 24
0.00×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AMST
AMST
VYNE
VYNE
Operating Cash FlowLast quarter
$-621.1K
$-10.8M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AMST
AMST
VYNE
VYNE
Q4 25
$-621.1K
Q3 25
$-415.8K
Q2 25
$-439.4K
$-10.8M
Q1 25
$-11.5M
Q4 24
$-9.0M
Q3 24
$-8.5M
Q2 24
$-8.5M
Q1 24
$-8.0M

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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