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Side-by-side financial comparison of AEMETIS, INC (AMTX) and OptimizeRx Corp (OPRX). Click either name above to swap in a different company.

AEMETIS, INC is the larger business by last-quarter revenue ($43.3M vs $32.2M, roughly 1.3× OptimizeRx Corp). On growth, OptimizeRx Corp posted the faster year-over-year revenue change (-0.2% vs -7.9%). OptimizeRx Corp produced more free cash flow last quarter ($7.1M vs $-10.8M). Over the past eight quarters, OptimizeRx Corp's revenue compounded faster (28.0% CAGR vs -22.8%).

Aemetis, Inc. is a renewable fuels and sustainable biochemicals producer operating across North America and India. Its core products include low-carbon ethanol, renewable natural gas and biodiesel, serving transportation, industrial and agricultural sectors with decarbonization solutions for commercial clients.

OptimizeRx Corp is a U.S.-headquartered digital health technology company that delivers patient engagement, medication affordability and clinical communication solutions to life sciences enterprises, healthcare providers and pharmacy partners. Its core offerings include digital medication savings tools, patient support programs, and therapeutic area-specific resources to boost medication access and treatment adherence.

AMTX vs OPRX — Head-to-Head

Bigger by revenue
AMTX
AMTX
1.3× larger
AMTX
$43.3M
$32.2M
OPRX
Growing faster (revenue YoY)
OPRX
OPRX
+7.6% gap
OPRX
-0.2%
-7.9%
AMTX
More free cash flow
OPRX
OPRX
$17.9M more FCF
OPRX
$7.1M
$-10.8M
AMTX
Faster 2-yr revenue CAGR
OPRX
OPRX
Annualised
OPRX
28.0%
-22.8%
AMTX

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AMTX
AMTX
OPRX
OPRX
Revenue
$43.3M
$32.2M
Net Profit
$5.0M
Gross Margin
17.8%
74.8%
Operating Margin
-5.7%
26.6%
Net Margin
15.6%
Revenue YoY
-7.9%
-0.2%
Net Profit YoY
6535.9%
EPS (diluted)
$-0.03
$0.27

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AMTX
AMTX
OPRX
OPRX
Q4 25
$43.3M
$32.2M
Q3 25
$59.2M
$26.1M
Q2 25
$52.2M
$29.2M
Q1 25
$42.9M
$21.9M
Q4 24
$47.0M
$32.3M
Q3 24
$81.4M
$21.3M
Q2 24
$66.6M
$18.8M
Q1 24
$72.6M
$19.7M
Net Profit
AMTX
AMTX
OPRX
OPRX
Q4 25
$5.0M
Q3 25
$-23.7M
$779.0K
Q2 25
$-23.4M
$1.5M
Q1 25
$-24.5M
$-2.2M
Q4 24
$-78.0K
Q3 24
$-17.9M
$-9.1M
Q2 24
$-29.2M
$-4.0M
Q1 24
$-24.2M
$-6.9M
Gross Margin
AMTX
AMTX
OPRX
OPRX
Q4 25
17.8%
74.8%
Q3 25
-0.1%
67.2%
Q2 25
-6.4%
63.8%
Q1 25
-11.8%
60.9%
Q4 24
-4.3%
68.1%
Q3 24
4.8%
63.1%
Q2 24
-2.7%
62.2%
Q1 24
-0.8%
62.0%
Operating Margin
AMTX
AMTX
OPRX
OPRX
Q4 25
-5.7%
26.6%
Q3 25
-14.4%
7.9%
Q2 25
-20.4%
10.9%
Q1 25
-36.3%
-9.6%
Q4 24
-28.7%
11.2%
Q3 24
-4.8%
-40.2%
Q2 24
-20.4%
-19.9%
Q1 24
-13.0%
-25.5%
Net Margin
AMTX
AMTX
OPRX
OPRX
Q4 25
15.6%
Q3 25
-40.1%
3.0%
Q2 25
-44.8%
5.2%
Q1 25
-57.2%
-10.0%
Q4 24
-0.2%
Q3 24
-22.0%
-42.8%
Q2 24
-43.8%
-21.3%
Q1 24
-33.4%
-35.0%
EPS (diluted)
AMTX
AMTX
OPRX
OPRX
Q4 25
$-0.03
$0.27
Q3 25
$-0.37
$0.04
Q2 25
$-0.41
$0.08
Q1 25
$-0.47
$-0.12
Q4 24
$-0.29
$0.00
Q3 24
$-0.38
$-0.50
Q2 24
$-0.66
$-0.22
Q1 24
$-0.58
$-0.38

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AMTX
AMTX
OPRX
OPRX
Cash + ST InvestmentsLiquidity on hand
$4.9M
$23.4M
Total DebtLower is stronger
$26.3M
Stockholders' EquityBook value
$-306.8M
$128.3M
Total Assets
$259.8M
$176.9M
Debt / EquityLower = less leverage
0.20×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AMTX
AMTX
OPRX
OPRX
Q4 25
$4.9M
$23.4M
Q3 25
$5.6M
$19.5M
Q2 25
$1.6M
$16.6M
Q1 25
$499.0K
$16.6M
Q4 24
$898.0K
$13.4M
Q3 24
$296.0K
$16.1M
Q2 24
$234.0K
Q1 24
$1.6M
Total Debt
AMTX
AMTX
OPRX
OPRX
Q4 25
$26.3M
Q3 25
$28.8M
Q2 25
$29.3M
Q1 25
$33.8M
Q4 24
$338.1M
$34.3M
Q3 24
$322.2M
$36.8M
Q2 24
$309.0M
$37.3M
Q1 24
$307.2M
$37.8M
Stockholders' Equity
AMTX
AMTX
OPRX
OPRX
Q4 25
$-306.8M
$128.3M
Q3 25
$-304.9M
$122.3M
Q2 25
$-289.3M
$119.3M
Q1 25
$-280.7M
$116.3M
Q4 24
$-263.9M
$117.0M
Q3 24
$-258.9M
$114.5M
Q2 24
$-249.0M
$121.0M
Q1 24
$-232.1M
$122.5M
Total Assets
AMTX
AMTX
OPRX
OPRX
Q4 25
$259.8M
$176.9M
Q3 25
$241.1M
$170.3M
Q2 25
$240.0M
$169.3M
Q1 25
$242.5M
$167.8M
Q4 24
$259.3M
$171.2M
Q3 24
$259.3M
$165.2M
Q2 24
$259.3M
$172.9M
Q1 24
$259.3M
$176.4M
Debt / Equity
AMTX
AMTX
OPRX
OPRX
Q4 25
0.20×
Q3 25
0.24×
Q2 25
0.25×
Q1 25
0.29×
Q4 24
0.29×
Q3 24
0.32×
Q2 24
0.31×
Q1 24
0.31×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AMTX
AMTX
OPRX
OPRX
Operating Cash FlowLast quarter
$5.8M
$7.1M
Free Cash FlowOCF − Capex
$-10.8M
$7.1M
FCF MarginFCF / Revenue
-24.9%
22.0%
Capex IntensityCapex / Revenue
38.2%
0.0%
Cash ConversionOCF / Net Profit
1.41×
TTM Free Cash FlowTrailing 4 quarters
$-22.7M
$18.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AMTX
AMTX
OPRX
OPRX
Q4 25
$5.8M
$7.1M
Q3 25
$3.1M
$3.2M
Q2 25
$-5.7M
$4.6M
Q1 25
$160.0K
$3.9M
Q4 24
$-12.6M
$198.0K
Q3 24
$-5.0M
$1.8M
Q2 24
$-5.1M
$782.0K
Q1 24
$-10.3M
$2.1M
Free Cash Flow
AMTX
AMTX
OPRX
OPRX
Q4 25
$-10.8M
$7.1M
Q3 25
$-1.0M
$3.2M
Q2 25
$-9.3M
$4.6M
Q1 25
$-1.7M
$3.8M
Q4 24
$-19.4M
$181.0K
Q3 24
$-9.5M
$1.8M
Q2 24
$-10.5M
$737.0K
Q1 24
$-13.9M
$2.1M
FCF Margin
AMTX
AMTX
OPRX
OPRX
Q4 25
-24.9%
22.0%
Q3 25
-1.7%
12.2%
Q2 25
-17.7%
15.6%
Q1 25
-3.9%
17.5%
Q4 24
-41.2%
0.6%
Q3 24
-11.6%
8.3%
Q2 24
-15.8%
3.9%
Q1 24
-19.1%
10.6%
Capex Intensity
AMTX
AMTX
OPRX
OPRX
Q4 25
38.2%
0.0%
Q3 25
6.9%
0.0%
Q2 25
6.7%
0.0%
Q1 25
4.3%
0.1%
Q4 24
14.4%
0.1%
Q3 24
5.5%
0.1%
Q2 24
8.1%
0.2%
Q1 24
4.9%
0.2%
Cash Conversion
AMTX
AMTX
OPRX
OPRX
Q4 25
1.41×
Q3 25
4.11×
Q2 25
2.98×
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AMTX
AMTX

Ethanol Sales$28.8M66%
Wet Distillers Grains$6.8M16%
California Dairy Renewable Natural Gas$5.2M12%
Other$1.8M4%

OPRX
OPRX

Segment breakdown not available.

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