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Side-by-side financial comparison of ANAPTYSBIO, INC (ANAB) and H2O AMERICA (HTO). Click either name above to swap in a different company.

H2O AMERICA is the larger business by last-quarter revenue ($199.4M vs $108.2M, roughly 1.8× ANAPTYSBIO, INC). ANAPTYSBIO, INC runs the higher net margin — 45.8% vs 8.1%, a 37.7% gap on every dollar of revenue. On growth, ANAPTYSBIO, INC posted the faster year-over-year revenue change (151.1% vs 1.5%). Over the past eight quarters, ANAPTYSBIO, INC's revenue compounded faster (288.3% CAGR vs 15.3%).

AnaptysBio, Inc. is a clinical-stage biotechnology company focused on developing antibody-based immunotherapies for inflammatory diseases, immuno-oncology indications, and rare disease conditions. It primarily serves the U.S. market, advancing its innovative product candidate pipeline to address unmet medical needs via rigorous research and clinical development.

H2O Wireless is a United States-based prepaid cell phone service, that utilizes the AT&T network. It is a brand of the mobile virtual network operator (MVNO) Locus Telecommunications, a subsidiary of Telrite Holdings, Inc., since 2019. Locus was formerly a subsidiary of KDDI America corporation, starting in 2010. H2O Wireless is primarily advertised as a non-restrictive phone service for customers to bring or buy unlocked smartphones, although AT&T contract/locked phones may be accepted as well.

ANAB vs HTO — Head-to-Head

Bigger by revenue
HTO
HTO
1.8× larger
HTO
$199.4M
$108.2M
ANAB
Growing faster (revenue YoY)
ANAB
ANAB
+149.6% gap
ANAB
151.1%
1.5%
HTO
Higher net margin
ANAB
ANAB
37.7% more per $
ANAB
45.8%
8.1%
HTO
Faster 2-yr revenue CAGR
ANAB
ANAB
Annualised
ANAB
288.3%
15.3%
HTO

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ANAB
ANAB
HTO
HTO
Revenue
$108.2M
$199.4M
Net Profit
$49.6M
$16.2M
Gross Margin
Operating Margin
61.8%
16.6%
Net Margin
45.8%
8.1%
Revenue YoY
151.1%
1.5%
Net Profit YoY
327.8%
-29.2%
EPS (diluted)
$1.64
$0.45

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ANAB
ANAB
HTO
HTO
Q4 25
$108.2M
$199.4M
Q3 25
$76.3M
$243.5M
Q2 25
$22.3M
$197.8M
Q1 25
$27.8M
$164.9M
Q4 24
$43.1M
$196.5M
Q3 24
$30.0M
$216.7M
Q2 24
$11.0M
$173.1M
Q1 24
$7.2M
$150.0M
Net Profit
ANAB
ANAB
HTO
HTO
Q4 25
$49.6M
$16.2M
Q3 25
$15.1M
$45.1M
Q2 25
$-38.6M
$24.7M
Q1 25
$-39.3M
$16.6M
Q4 24
$-21.8M
$22.9M
Q3 24
$-32.9M
$38.7M
Q2 24
$-46.7M
$20.7M
Q1 24
$-43.9M
$11.7M
Operating Margin
ANAB
ANAB
HTO
HTO
Q4 25
61.8%
16.6%
Q3 25
45.5%
26.5%
Q2 25
-117.5%
22.2%
Q1 25
-99.2%
21.8%
Q4 24
-22.4%
22.2%
Q3 24
-75.8%
26.9%
Q2 24
-367.5%
23.4%
Q1 24
-587.8%
18.6%
Net Margin
ANAB
ANAB
HTO
HTO
Q4 25
45.8%
8.1%
Q3 25
19.8%
18.5%
Q2 25
-173.5%
12.5%
Q1 25
-141.6%
10.0%
Q4 24
-50.5%
11.7%
Q3 24
-109.4%
17.8%
Q2 24
-425.3%
12.0%
Q1 24
-612.0%
7.8%
EPS (diluted)
ANAB
ANAB
HTO
HTO
Q4 25
$1.64
$0.45
Q3 25
$0.52
$1.27
Q2 25
$-1.34
$0.71
Q1 25
$-1.28
$0.49
Q4 24
$-0.63
$0.70
Q3 24
$-1.14
$1.17
Q2 24
$-1.71
$0.64
Q1 24
$-1.64
$0.36

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ANAB
ANAB
HTO
HTO
Cash + ST InvestmentsLiquidity on hand
$238.2M
$20.7M
Total DebtLower is stronger
$1.9B
Stockholders' EquityBook value
$37.2M
$1.5B
Total Assets
$364.4M
$5.1B
Debt / EquityLower = less leverage
1.23×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ANAB
ANAB
HTO
HTO
Q4 25
$238.2M
$20.7M
Q3 25
$109.8M
$11.3M
Q2 25
$44.3M
$19.8M
Q1 25
$98.6M
$23.7M
Q4 24
$123.1M
$11.1M
Q3 24
$191.6M
$4.0M
Q2 24
$71.8M
$22.8M
Q1 24
$53.7M
$4.5M
Total Debt
ANAB
ANAB
HTO
HTO
Q4 25
$1.9B
Q3 25
Q2 25
Q1 25
Q4 24
$1.7B
Q3 24
Q2 24
Q1 24
Stockholders' Equity
ANAB
ANAB
HTO
HTO
Q4 25
$37.2M
$1.5B
Q3 25
$-29.4M
$1.5B
Q2 25
$-44.7M
$1.5B
Q1 25
$34.0M
$1.4B
Q4 24
$70.9M
$1.4B
Q3 24
$84.4M
$1.3B
Q2 24
$9.9M
$1.3B
Q1 24
$47.8M
$1.2B
Total Assets
ANAB
ANAB
HTO
HTO
Q4 25
$364.4M
$5.1B
Q3 25
$353.1M
$5.0B
Q2 25
$335.3M
$4.8B
Q1 25
$422.1M
$4.7B
Q4 24
$483.8M
$4.7B
Q3 24
$493.4M
$4.6B
Q2 24
$427.4M
$4.4B
Q1 24
$405.8M
$4.4B
Debt / Equity
ANAB
ANAB
HTO
HTO
Q4 25
1.23×
Q3 25
Q2 25
Q1 25
Q4 24
1.26×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ANAB
ANAB
HTO
HTO
Operating Cash FlowLast quarter
$98.0M
$63.5M
Free Cash FlowOCF − Capex
$98.0M
FCF MarginFCF / Revenue
90.5%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
1.98×
3.92×
TTM Free Cash FlowTrailing 4 quarters
$19.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ANAB
ANAB
HTO
HTO
Q4 25
$98.0M
$63.5M
Q3 25
$-27.4M
$77.3M
Q2 25
$-40.2M
$60.8M
Q1 25
$-10.7M
$43.2M
Q4 24
$-66.7M
$41.5M
Q3 24
$-10.1M
$53.5M
Q2 24
$-21.3M
$49.3M
Q1 24
$-37.3M
$51.2M
Free Cash Flow
ANAB
ANAB
HTO
HTO
Q4 25
$98.0M
Q3 25
$-27.4M
Q2 25
$-40.3M
Q1 25
$-10.7M
Q4 24
$-66.9M
Q3 24
$-10.1M
Q2 24
$-21.4M
Q1 24
$-37.3M
FCF Margin
ANAB
ANAB
HTO
HTO
Q4 25
90.5%
Q3 25
-35.9%
Q2 25
-180.9%
Q1 25
-38.7%
Q4 24
-155.3%
Q3 24
-33.7%
Q2 24
-194.6%
Q1 24
-519.3%
Capex Intensity
ANAB
ANAB
HTO
HTO
Q4 25
0.0%
Q3 25
0.0%
Q2 25
0.2%
Q1 25
0.1%
Q4 24
0.6%
Q3 24
0.1%
Q2 24
0.3%
Q1 24
0.4%
Cash Conversion
ANAB
ANAB
HTO
HTO
Q4 25
1.98×
3.92×
Q3 25
-1.81×
1.71×
Q2 25
2.47×
Q1 25
2.61×
Q4 24
1.81×
Q3 24
1.39×
Q2 24
2.38×
Q1 24
4.38×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ANAB
ANAB

Segment breakdown not available.

HTO
HTO

Water Utility Services$191.0M96%
Other$8.4M4%

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