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Side-by-side financial comparison of Apellis Pharmaceuticals, Inc. (APLS) and Mission Produce, Inc. (AVO). Click either name above to swap in a different company.

Mission Produce, Inc. is the larger business by last-quarter revenue ($319.0M vs $199.9M, roughly 1.6× Apellis Pharmaceuticals, Inc.). Mission Produce, Inc. runs the higher net margin — 5.0% vs -29.5%, a 34.5% gap on every dollar of revenue. On growth, Apellis Pharmaceuticals, Inc. posted the faster year-over-year revenue change (-5.9% vs -10.0%). Mission Produce, Inc. produced more free cash flow last quarter ($55.6M vs $-14.3M). Over the past eight quarters, Mission Produce, Inc.'s revenue compounded faster (11.0% CAGR vs 7.7%).

Apellis Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing targeted therapies that modulate the complement system to address serious unmet medical needs. Its core products target ophthalmic conditions like geographic atrophy secondary to age-related macular degeneration, as well as rare hematological and autoimmune disorders, with primary operations in the United States and European markets.

Produce Co., Ltd. was a Japanese video game company. Founded on April 6, 1990 by former Irem employees, it developed a number of games for both Enix and Hudson Soft. Produce! have created games for arcades and for the Super Nintendo Entertainment System, Nintendo 64, PlayStation, and PC Engine systems.

APLS vs AVO — Head-to-Head

Bigger by revenue
AVO
AVO
1.6× larger
AVO
$319.0M
$199.9M
APLS
Growing faster (revenue YoY)
APLS
APLS
+4.1% gap
APLS
-5.9%
-10.0%
AVO
Higher net margin
AVO
AVO
34.5% more per $
AVO
5.0%
-29.5%
APLS
More free cash flow
AVO
AVO
$69.9M more FCF
AVO
$55.6M
$-14.3M
APLS
Faster 2-yr revenue CAGR
AVO
AVO
Annualised
AVO
11.0%
7.7%
APLS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
APLS
APLS
AVO
AVO
Revenue
$199.9M
$319.0M
Net Profit
$-59.0M
$16.0M
Gross Margin
17.5%
Operating Margin
-25.6%
8.8%
Net Margin
-29.5%
5.0%
Revenue YoY
-5.9%
-10.0%
Net Profit YoY
-62.2%
-7.5%
EPS (diluted)
$-0.40
$0.23

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APLS
APLS
AVO
AVO
Q4 25
$199.9M
$319.0M
Q3 25
$458.6M
$357.7M
Q2 25
$178.5M
$380.3M
Q1 25
$166.8M
$334.2M
Q4 24
$212.5M
$354.4M
Q3 24
$196.8M
$324.0M
Q2 24
$199.7M
$297.6M
Q1 24
$172.3M
$258.7M
Net Profit
APLS
APLS
AVO
AVO
Q4 25
$-59.0M
$16.0M
Q3 25
$215.7M
$14.7M
Q2 25
$-42.2M
$3.1M
Q1 25
$-92.2M
$3.9M
Q4 24
$-36.4M
$17.3M
Q3 24
$-57.4M
$12.4M
Q2 24
$-37.7M
$7.0M
Q1 24
$-66.4M
$0
Gross Margin
APLS
APLS
AVO
AVO
Q4 25
17.5%
Q3 25
12.6%
Q2 25
7.5%
Q1 25
9.4%
Q4 24
15.7%
Q3 24
11.4%
Q2 24
10.4%
Q1 24
11.1%
Operating Margin
APLS
APLS
AVO
AVO
Q4 25
-25.6%
8.8%
Q3 25
48.7%
5.9%
Q2 25
-18.6%
1.8%
Q1 25
-50.0%
2.8%
Q4 24
-12.3%
8.1%
Q3 24
-24.0%
5.2%
Q2 24
-14.7%
4.1%
Q1 24
-36.0%
3.1%
Net Margin
APLS
APLS
AVO
AVO
Q4 25
-29.5%
5.0%
Q3 25
47.0%
4.1%
Q2 25
-23.6%
0.8%
Q1 25
-55.3%
1.2%
Q4 24
-17.1%
4.9%
Q3 24
-29.2%
3.8%
Q2 24
-18.9%
2.4%
Q1 24
-38.5%
EPS (diluted)
APLS
APLS
AVO
AVO
Q4 25
$-0.40
$0.23
Q3 25
$1.67
$0.21
Q2 25
$-0.33
$0.04
Q1 25
$-0.74
$0.05
Q4 24
$-0.30
$0.25
Q3 24
$-0.46
$0.17
Q2 24
$-0.30
$0.10
Q1 24
$-0.54
$0.00

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APLS
APLS
AVO
AVO
Cash + ST InvestmentsLiquidity on hand
$466.2M
$64.8M
Total DebtLower is stronger
$95.8M
Stockholders' EquityBook value
$370.1M
$587.3M
Total Assets
$1.1B
$983.0M
Debt / EquityLower = less leverage
0.16×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APLS
APLS
AVO
AVO
Q4 25
$466.2M
$64.8M
Q3 25
$479.2M
$43.7M
Q2 25
$370.0M
$36.7M
Q1 25
$358.4M
$40.1M
Q4 24
$411.3M
$58.0M
Q3 24
$396.9M
$49.5M
Q2 24
$360.1M
$46.2M
Q1 24
$325.9M
$39.9M
Total Debt
APLS
APLS
AVO
AVO
Q4 25
$95.8M
Q3 25
$131.5M
Q2 25
$147.2M
Q1 25
$117.9M
Q4 24
$113.7M
Q3 24
$134.4M
Q2 24
$170.2M
Q1 24
$93.1M
$156.1M
Stockholders' Equity
APLS
APLS
AVO
AVO
Q4 25
$370.1M
$587.3M
Q3 25
$401.2M
$568.7M
Q2 25
$156.3M
$552.3M
Q1 25
$164.2M
$550.8M
Q4 24
$228.5M
$547.3M
Q3 24
$237.1M
$527.3M
Q2 24
$264.3M
$513.3M
Q1 24
$266.7M
$505.1M
Total Assets
APLS
APLS
AVO
AVO
Q4 25
$1.1B
$983.0M
Q3 25
$1.1B
$1.0B
Q2 25
$821.4M
$1.0B
Q1 25
$807.3M
$997.8M
Q4 24
$885.1M
$971.5M
Q3 24
$901.9M
$959.9M
Q2 24
$904.5M
$966.9M
Q1 24
$831.9M
$937.5M
Debt / Equity
APLS
APLS
AVO
AVO
Q4 25
0.16×
Q3 25
0.23×
Q2 25
0.27×
Q1 25
0.21×
Q4 24
0.21×
Q3 24
0.25×
Q2 24
0.33×
Q1 24
0.35×
0.31×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APLS
APLS
AVO
AVO
Operating Cash FlowLast quarter
$-14.2M
$67.2M
Free Cash FlowOCF − Capex
$-14.3M
$55.6M
FCF MarginFCF / Revenue
-7.1%
17.4%
Capex IntensityCapex / Revenue
0.1%
3.6%
Cash ConversionOCF / Net Profit
4.20×
TTM Free Cash FlowTrailing 4 quarters
$45.0M
$37.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APLS
APLS
AVO
AVO
Q4 25
$-14.2M
$67.2M
Q3 25
$108.5M
$34.4M
Q2 25
$4.4M
$-11.8M
Q1 25
$-53.4M
$-1.2M
Q4 24
$19.4M
$38.0M
Q3 24
$34.1M
$42.5M
Q2 24
$-8.3M
$3.4M
Q1 24
$-133.0M
$9.5M
Free Cash Flow
APLS
APLS
AVO
AVO
Q4 25
$-14.3M
$55.6M
Q3 25
$108.3M
$22.6M
Q2 25
$4.4M
$-25.0M
Q1 25
$-53.4M
$-16.0M
Q4 24
$19.3M
$31.1M
Q3 24
$34.9M
Q2 24
$-8.4M
$-4.4M
Q1 24
$-133.3M
$-400.0K
FCF Margin
APLS
APLS
AVO
AVO
Q4 25
-7.1%
17.4%
Q3 25
23.6%
6.3%
Q2 25
2.5%
-6.6%
Q1 25
-32.0%
-4.8%
Q4 24
9.1%
8.8%
Q3 24
10.8%
Q2 24
-4.2%
-1.5%
Q1 24
-77.3%
-0.2%
Capex Intensity
APLS
APLS
AVO
AVO
Q4 25
0.1%
3.6%
Q3 25
0.0%
3.3%
Q2 25
0.0%
3.5%
Q1 25
0.0%
4.4%
Q4 24
0.0%
1.9%
Q3 24
0.0%
2.3%
Q2 24
0.0%
2.6%
Q1 24
0.2%
3.8%
Cash Conversion
APLS
APLS
AVO
AVO
Q4 25
4.20×
Q3 25
0.50×
2.34×
Q2 25
-3.81×
Q1 25
-0.31×
Q4 24
2.20×
Q3 24
3.43×
Q2 24
0.49×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APLS
APLS

Syfovre$155.2M78%
Empaveli Pegcetacoplan$35.1M18%
Licensing And Other Revenue$9.6M5%

AVO
AVO

Avocado$256.9M81%
Blueberry$36.5M11%
Mango$18.7M6%
Other$6.9M2%

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