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Side-by-side financial comparison of Apellis Pharmaceuticals, Inc. (APLS) and Core Laboratories Inc. (CLB). Click either name above to swap in a different company.

Apellis Pharmaceuticals, Inc. is the larger business by last-quarter revenue ($199.9M vs $138.3M, roughly 1.4× Core Laboratories Inc.). Core Laboratories Inc. runs the higher net margin — 5.3% vs -29.5%, a 34.7% gap on every dollar of revenue. On growth, Core Laboratories Inc. posted the faster year-over-year revenue change (2.8% vs -5.9%). Core Laboratories Inc. produced more free cash flow last quarter ($5.1M vs $-14.3M). Over the past eight quarters, Apellis Pharmaceuticals, Inc.'s revenue compounded faster (7.7% CAGR vs 2.9%).

Apellis Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing targeted therapies that modulate the complement system to address serious unmet medical needs. Its core products target ophthalmic conditions like geographic atrophy secondary to age-related macular degeneration, as well as rare hematological and autoimmune disorders, with primary operations in the United States and European markets.

Abbott Laboratories, commonly known as Abbott, is an American multinational medical devices and health care company with headquarters in Abbott Park, Illinois. The company produces pharmaceuticals for sale outside the United States, diagnostic products, nutritional products, and medical devices.

APLS vs CLB — Head-to-Head

Bigger by revenue
APLS
APLS
1.4× larger
APLS
$199.9M
$138.3M
CLB
Growing faster (revenue YoY)
CLB
CLB
+8.7% gap
CLB
2.8%
-5.9%
APLS
Higher net margin
CLB
CLB
34.7% more per $
CLB
5.3%
-29.5%
APLS
More free cash flow
CLB
CLB
$19.4M more FCF
CLB
$5.1M
$-14.3M
APLS
Faster 2-yr revenue CAGR
APLS
APLS
Annualised
APLS
7.7%
2.9%
CLB

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
APLS
APLS
CLB
CLB
Revenue
$199.9M
$138.3M
Net Profit
$-59.0M
$7.3M
Gross Margin
Operating Margin
-25.6%
11.5%
Net Margin
-29.5%
5.3%
Revenue YoY
-5.9%
2.8%
Net Profit YoY
-62.2%
1.2%
EPS (diluted)
$-0.40
$0.16

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APLS
APLS
CLB
CLB
Q1 26
$138.3M
Q4 25
$199.9M
$138.3M
Q3 25
$458.6M
$134.5M
Q2 25
$178.5M
$130.2M
Q1 25
$166.8M
$123.6M
Q4 24
$212.5M
$129.2M
Q3 24
$196.8M
$134.4M
Q2 24
$199.7M
$130.6M
Net Profit
APLS
APLS
CLB
CLB
Q1 26
$7.3M
Q4 25
$-59.0M
$4.9M
Q3 25
$215.7M
$14.2M
Q2 25
$-42.2M
$10.6M
Q1 25
$-92.2M
$-154.0K
Q4 24
$-36.4M
$7.4M
Q3 24
$-57.4M
$11.7M
Q2 24
$-37.7M
$9.0M
Gross Margin
APLS
APLS
CLB
CLB
Q1 26
Q4 25
20.8%
Q3 25
22.0%
Q2 25
20.3%
Q1 25
19.5%
Q4 24
17.8%
Q3 24
20.5%
Q2 24
21.2%
Operating Margin
APLS
APLS
CLB
CLB
Q1 26
11.5%
Q4 25
-25.6%
11.5%
Q3 25
48.7%
15.6%
Q2 25
-18.6%
11.7%
Q1 25
-50.0%
3.6%
Q4 24
-12.3%
11.0%
Q3 24
-24.0%
14.7%
Q2 24
-14.7%
12.3%
Net Margin
APLS
APLS
CLB
CLB
Q1 26
5.3%
Q4 25
-29.5%
3.6%
Q3 25
47.0%
10.6%
Q2 25
-23.6%
8.2%
Q1 25
-55.3%
-0.1%
Q4 24
-17.1%
5.7%
Q3 24
-29.2%
8.7%
Q2 24
-18.9%
6.9%
EPS (diluted)
APLS
APLS
CLB
CLB
Q1 26
$0.16
Q4 25
$-0.40
$0.11
Q3 25
$1.67
$0.30
Q2 25
$-0.33
$0.22
Q1 25
$-0.74
$0.00
Q4 24
$-0.30
$0.15
Q3 24
$-0.46
$0.25
Q2 24
$-0.30
$0.19

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APLS
APLS
CLB
CLB
Cash + ST InvestmentsLiquidity on hand
$466.2M
$22.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$370.1M
$279.8M
Total Assets
$1.1B
$597.0M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APLS
APLS
CLB
CLB
Q1 26
$22.8M
Q4 25
$466.2M
$22.7M
Q3 25
$479.2M
$25.6M
Q2 25
$370.0M
$31.2M
Q1 25
$358.4M
$22.1M
Q4 24
$411.3M
$19.2M
Q3 24
$396.9M
$21.5M
Q2 24
$360.1M
$17.7M
Total Debt
APLS
APLS
CLB
CLB
Q1 26
Q4 25
$110.3M
Q3 25
$114.1M
Q2 25
$124.6M
Q1 25
$124.4M
Q4 24
$126.1M
Q3 24
$139.9M
Q2 24
$147.6M
Stockholders' Equity
APLS
APLS
CLB
CLB
Q1 26
$279.8M
Q4 25
$370.1M
$266.0M
Q3 25
$401.2M
$271.3M
Q2 25
$156.3M
$261.3M
Q1 25
$164.2M
$253.4M
Q4 24
$228.5M
$246.6M
Q3 24
$237.1M
$250.7M
Q2 24
$264.3M
$240.3M
Total Assets
APLS
APLS
CLB
CLB
Q1 26
$597.0M
Q4 25
$1.1B
$584.0M
Q3 25
$1.1B
$591.4M
Q2 25
$821.4M
$602.1M
Q1 25
$807.3M
$591.5M
Q4 24
$885.1M
$585.1M
Q3 24
$901.9M
$600.5M
Q2 24
$904.5M
$597.8M
Debt / Equity
APLS
APLS
CLB
CLB
Q1 26
Q4 25
0.41×
Q3 25
0.42×
Q2 25
0.48×
Q1 25
0.49×
Q4 24
0.51×
Q3 24
0.56×
Q2 24
0.61×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APLS
APLS
CLB
CLB
Operating Cash FlowLast quarter
$-14.2M
$37.2M
Free Cash FlowOCF − Capex
$-14.3M
$5.1M
FCF MarginFCF / Revenue
-7.1%
3.7%
Capex IntensityCapex / Revenue
0.1%
Cash ConversionOCF / Net Profit
5.12×
TTM Free Cash FlowTrailing 4 quarters
$45.0M
$27.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APLS
APLS
CLB
CLB
Q1 26
$37.2M
Q4 25
$-14.2M
$7.9M
Q3 25
$108.5M
$8.5M
Q2 25
$4.4M
$13.9M
Q1 25
$-53.4M
$6.7M
Q4 24
$19.4M
$20.6M
Q3 24
$34.1M
$13.1M
Q2 24
$-8.3M
$17.1M
Free Cash Flow
APLS
APLS
CLB
CLB
Q1 26
$5.1M
Q4 25
$-14.3M
$5.0M
Q3 25
$108.3M
$6.5M
Q2 25
$4.4M
$10.4M
Q1 25
$-53.4M
$3.9M
Q4 24
$19.3M
$17.4M
Q3 24
$10.4M
Q2 24
$-8.4M
$14.3M
FCF Margin
APLS
APLS
CLB
CLB
Q1 26
3.7%
Q4 25
-7.1%
3.6%
Q3 25
23.6%
4.8%
Q2 25
2.5%
8.0%
Q1 25
-32.0%
3.1%
Q4 24
9.1%
13.4%
Q3 24
7.7%
Q2 24
-4.2%
10.9%
Capex Intensity
APLS
APLS
CLB
CLB
Q1 26
Q4 25
0.1%
2.1%
Q3 25
0.0%
1.5%
Q2 25
0.0%
2.7%
Q1 25
0.0%
2.3%
Q4 24
0.0%
2.5%
Q3 24
0.0%
2.0%
Q2 24
0.0%
2.2%
Cash Conversion
APLS
APLS
CLB
CLB
Q1 26
5.12×
Q4 25
1.61×
Q3 25
0.50×
0.60×
Q2 25
1.31×
Q1 25
Q4 24
2.78×
Q3 24
1.12×
Q2 24
1.90×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APLS
APLS

Syfovre$155.2M78%
Empaveli Pegcetacoplan$35.1M18%
Licensing And Other Revenue$9.6M5%

CLB
CLB

Segment breakdown not available.

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