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Side-by-side financial comparison of Apellis Pharmaceuticals, Inc. (APLS) and MACH NATURAL RESOURCES LP (MNR). Click either name above to swap in a different company.

MACH NATURAL RESOURCES LP is the larger business by last-quarter revenue ($387.5M vs $199.9M, roughly 1.9× Apellis Pharmaceuticals, Inc.). MACH NATURAL RESOURCES LP runs the higher net margin — 18.9% vs -29.5%, a 48.3% gap on every dollar of revenue. On growth, MACH NATURAL RESOURCES LP posted the faster year-over-year revenue change (65.0% vs -5.9%). Over the past eight quarters, MACH NATURAL RESOURCES LP's revenue compounded faster (27.3% CAGR vs 7.7%).

Apellis Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing targeted therapies that modulate the complement system to address serious unmet medical needs. Its core products target ophthalmic conditions like geographic atrophy secondary to age-related macular degeneration, as well as rare hematological and autoimmune disorders, with primary operations in the United States and European markets.

Mach Natural Resources LP is a US-based upstream energy enterprise focused on the exploration, development, and production of oil, natural gas, and natural gas liquids. Its core operations are located in onshore US hydrocarbon basins including the Permian Basin, prioritizing low-cost, high-yield assets to drive sustainable returns for stakeholders.

APLS vs MNR — Head-to-Head

Bigger by revenue
MNR
MNR
1.9× larger
MNR
$387.5M
$199.9M
APLS
Growing faster (revenue YoY)
MNR
MNR
+70.9% gap
MNR
65.0%
-5.9%
APLS
Higher net margin
MNR
MNR
48.3% more per $
MNR
18.9%
-29.5%
APLS
Faster 2-yr revenue CAGR
MNR
MNR
Annualised
MNR
27.3%
7.7%
APLS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
APLS
APLS
MNR
MNR
Revenue
$199.9M
$387.5M
Net Profit
$-59.0M
$73.1M
Gross Margin
Operating Margin
-25.6%
26.1%
Net Margin
-29.5%
18.9%
Revenue YoY
-5.9%
65.0%
Net Profit YoY
-62.2%
100.2%
EPS (diluted)
$-0.40
$0.47

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APLS
APLS
MNR
MNR
Q4 25
$199.9M
$387.5M
Q3 25
$458.6M
$272.6M
Q2 25
$178.5M
$288.5M
Q1 25
$166.8M
$226.8M
Q4 24
$212.5M
$234.9M
Q3 24
$196.8M
$255.5M
Q2 24
$199.7M
$240.0M
Q1 24
$172.3M
$239.2M
Net Profit
APLS
APLS
MNR
MNR
Q4 25
$-59.0M
$73.1M
Q3 25
$215.7M
$-35.7M
Q2 25
$-42.2M
$89.7M
Q1 25
$-92.2M
$15.9M
Q4 24
$-36.4M
$36.5M
Q3 24
$-57.4M
$67.4M
Q2 24
$-37.7M
$39.5M
Q1 24
$-66.4M
$41.7M
Operating Margin
APLS
APLS
MNR
MNR
Q4 25
-25.6%
26.1%
Q3 25
48.7%
-7.0%
Q2 25
-18.6%
38.6%
Q1 25
-50.0%
22.8%
Q4 24
-12.3%
24.9%
Q3 24
-24.0%
37.1%
Q2 24
-14.7%
29.4%
Q1 24
-36.0%
28.1%
Net Margin
APLS
APLS
MNR
MNR
Q4 25
-29.5%
18.9%
Q3 25
47.0%
-13.1%
Q2 25
-23.6%
31.1%
Q1 25
-55.3%
7.0%
Q4 24
-17.1%
15.5%
Q3 24
-29.2%
26.4%
Q2 24
-18.9%
16.5%
Q1 24
-38.5%
17.4%
EPS (diluted)
APLS
APLS
MNR
MNR
Q4 25
$-0.40
$0.47
Q3 25
$1.67
$-0.28
Q2 25
$-0.33
$0.76
Q1 25
$-0.74
$0.14
Q4 24
$-0.30
$0.34
Q3 24
$-0.46
$0.70
Q2 24
$-0.30
$0.42
Q1 24
$-0.54
$0.44

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APLS
APLS
MNR
MNR
Cash + ST InvestmentsLiquidity on hand
$466.2M
$42.6M
Total DebtLower is stronger
Stockholders' EquityBook value
$370.1M
Total Assets
$1.1B
$3.8B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APLS
APLS
MNR
MNR
Q4 25
$466.2M
$42.6M
Q3 25
$479.2M
$53.6M
Q2 25
$370.0M
$13.8M
Q1 25
$358.4M
$7.8M
Q4 24
$411.3M
$105.8M
Q3 24
$396.9M
$184.5M
Q2 24
$360.1M
$144.6M
Q1 24
$325.9M
$151.3M
Total Debt
APLS
APLS
MNR
MNR
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
$93.1M
Stockholders' Equity
APLS
APLS
MNR
MNR
Q4 25
$370.1M
Q3 25
$401.2M
Q2 25
$156.3M
Q1 25
$164.2M
Q4 24
$228.5M
Q3 24
$237.1M
Q2 24
$264.3M
Q1 24
$266.7M
Total Assets
APLS
APLS
MNR
MNR
Q4 25
$1.1B
$3.8B
Q3 25
$1.1B
$3.8B
Q2 25
$821.4M
$2.3B
Q1 25
$807.3M
$2.2B
Q4 24
$885.1M
$2.3B
Q3 24
$901.9M
$2.3B
Q2 24
$904.5M
$2.2B
Q1 24
$831.9M
$2.3B
Debt / Equity
APLS
APLS
MNR
MNR
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
0.35×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APLS
APLS
MNR
MNR
Operating Cash FlowLast quarter
$-14.2M
$128.7M
Free Cash FlowOCF − Capex
$-14.3M
FCF MarginFCF / Revenue
-7.1%
Capex IntensityCapex / Revenue
0.1%
Cash ConversionOCF / Net Profit
1.76×
TTM Free Cash FlowTrailing 4 quarters
$45.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APLS
APLS
MNR
MNR
Q4 25
$-14.2M
$128.7M
Q3 25
$108.5M
$105.5M
Q2 25
$4.4M
$130.1M
Q1 25
$-53.4M
$142.5M
Q4 24
$19.4M
$133.7M
Q3 24
$34.1M
$110.8M
Q2 24
$-8.3M
$116.8M
Q1 24
$-133.0M
$144.0M
Free Cash Flow
APLS
APLS
MNR
MNR
Q4 25
$-14.3M
Q3 25
$108.3M
Q2 25
$4.4M
Q1 25
$-53.4M
Q4 24
$19.3M
Q3 24
Q2 24
$-8.4M
Q1 24
$-133.3M
FCF Margin
APLS
APLS
MNR
MNR
Q4 25
-7.1%
Q3 25
23.6%
Q2 25
2.5%
Q1 25
-32.0%
Q4 24
9.1%
Q3 24
Q2 24
-4.2%
Q1 24
-77.3%
Capex Intensity
APLS
APLS
MNR
MNR
Q4 25
0.1%
Q3 25
0.0%
Q2 25
0.0%
Q1 25
0.0%
Q4 24
0.0%
Q3 24
0.0%
Q2 24
0.0%
Q1 24
0.2%
Cash Conversion
APLS
APLS
MNR
MNR
Q4 25
1.76×
Q3 25
0.50×
Q2 25
1.45×
Q1 25
8.97×
Q4 24
3.66×
Q3 24
1.64×
Q2 24
2.96×
Q1 24
3.45×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APLS
APLS

Syfovre$155.2M78%
Empaveli Pegcetacoplan$35.1M18%
Licensing And Other Revenue$9.6M5%

MNR
MNR

Oil Gas And Natural Gas Liquids Net$331.0M85%
Natural Gas Liquids Reserves$44.8M12%
Natural Gas Midstream$8.6M2%
Products$6.3M2%

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