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Side-by-side financial comparison of Apellis Pharmaceuticals, Inc. (APLS) and SkyWater Technology, Inc (SKYT). Click either name above to swap in a different company.

Apellis Pharmaceuticals, Inc. is the larger business by last-quarter revenue ($199.9M vs $171.0M, roughly 1.2× SkyWater Technology, Inc). SkyWater Technology, Inc runs the higher net margin — -4.5% vs -29.5%, a 24.9% gap on every dollar of revenue. On growth, SkyWater Technology, Inc posted the faster year-over-year revenue change (126.6% vs -5.9%). Apellis Pharmaceuticals, Inc. produced more free cash flow last quarter ($-14.3M vs $-42.2M). Over the past eight quarters, SkyWater Technology, Inc's revenue compounded faster (46.6% CAGR vs 7.7%).

Apellis Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing targeted therapies that modulate the complement system to address serious unmet medical needs. Its core products target ophthalmic conditions like geographic atrophy secondary to age-related macular degeneration, as well as rare hematological and autoimmune disorders, with primary operations in the United States and European markets.

SkyWater Technology, Inc. is an American semiconductor engineering and fabrication foundry, based in Bloomington, Minnesota. It is the only US-owned pure-play silicon foundry.

APLS vs SKYT — Head-to-Head

Bigger by revenue
APLS
APLS
1.2× larger
APLS
$199.9M
$171.0M
SKYT
Growing faster (revenue YoY)
SKYT
SKYT
+132.5% gap
SKYT
126.6%
-5.9%
APLS
Higher net margin
SKYT
SKYT
24.9% more per $
SKYT
-4.5%
-29.5%
APLS
More free cash flow
APLS
APLS
$27.9M more FCF
APLS
$-14.3M
$-42.2M
SKYT
Faster 2-yr revenue CAGR
SKYT
SKYT
Annualised
SKYT
46.6%
7.7%
APLS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
APLS
APLS
SKYT
SKYT
Revenue
$199.9M
$171.0M
Net Profit
$-59.0M
$-7.8M
Gross Margin
14.9%
Operating Margin
-25.6%
0.0%
Net Margin
-29.5%
-4.5%
Revenue YoY
-5.9%
126.6%
Net Profit YoY
-62.2%
-1045.8%
EPS (diluted)
$-0.40
$-0.15

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APLS
APLS
SKYT
SKYT
Q4 25
$199.9M
$171.0M
Q3 25
$458.6M
$150.7M
Q2 25
$178.5M
$59.1M
Q1 25
$166.8M
$61.3M
Q4 24
$212.5M
$75.5M
Q3 24
$196.8M
$93.8M
Q2 24
$199.7M
$93.3M
Q1 24
$172.3M
$79.6M
Net Profit
APLS
APLS
SKYT
SKYT
Q4 25
$-59.0M
$-7.8M
Q3 25
$215.7M
$144.0M
Q2 25
$-42.2M
$-10.0M
Q1 25
$-92.2M
$-7.3M
Q4 24
$-36.4M
$-679.0K
Q3 24
$-57.4M
$1.5M
Q2 24
$-37.7M
$-1.9M
Q1 24
$-66.4M
$-5.7M
Gross Margin
APLS
APLS
SKYT
SKYT
Q4 25
14.9%
Q3 25
24.0%
Q2 25
18.5%
Q1 25
23.3%
Q4 24
25.6%
Q3 24
21.6%
Q2 24
18.3%
Q1 24
16.3%
Operating Margin
APLS
APLS
SKYT
SKYT
Q4 25
-25.6%
0.0%
Q3 25
48.7%
5.2%
Q2 25
-18.6%
-11.0%
Q1 25
-50.0%
-6.6%
Q4 24
-12.3%
3.5%
Q3 24
-24.0%
5.0%
Q2 24
-14.7%
1.5%
Q1 24
-36.0%
-2.8%
Net Margin
APLS
APLS
SKYT
SKYT
Q4 25
-29.5%
-4.5%
Q3 25
47.0%
95.5%
Q2 25
-23.6%
-16.9%
Q1 25
-55.3%
-12.0%
Q4 24
-17.1%
-0.9%
Q3 24
-29.2%
1.6%
Q2 24
-18.9%
-2.0%
Q1 24
-38.5%
-7.2%
EPS (diluted)
APLS
APLS
SKYT
SKYT
Q4 25
$-0.40
$-0.15
Q3 25
$1.67
$2.95
Q2 25
$-0.33
$-0.21
Q1 25
$-0.74
$-0.15
Q4 24
$-0.30
$-0.01
Q3 24
$-0.46
$0.03
Q2 24
$-0.30
$-0.04
Q1 24
$-0.54
$-0.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APLS
APLS
SKYT
SKYT
Cash + ST InvestmentsLiquidity on hand
$466.2M
$23.2M
Total DebtLower is stronger
$38.9M
Stockholders' EquityBook value
$370.1M
$187.8M
Total Assets
$1.1B
$733.9M
Debt / EquityLower = less leverage
0.21×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APLS
APLS
SKYT
SKYT
Q4 25
$466.2M
$23.2M
Q3 25
$479.2M
$30.9M
Q2 25
$370.0M
$49.4M
Q1 25
$358.4M
$51.2M
Q4 24
$411.3M
$18.8M
Q3 24
$396.9M
$20.7M
Q2 24
$360.1M
$18.4M
Q1 24
$325.9M
$20.0M
Total Debt
APLS
APLS
SKYT
SKYT
Q4 25
$38.9M
Q3 25
$40.4M
Q2 25
$42.1M
Q1 25
$38.6M
Q4 24
$39.8M
Q3 24
$41.3M
Q2 24
$42.4M
Q1 24
$93.1M
$39.3M
Stockholders' Equity
APLS
APLS
SKYT
SKYT
Q4 25
$370.1M
$187.8M
Q3 25
$401.2M
$192.8M
Q2 25
$156.3M
$45.2M
Q1 25
$164.2M
$53.4M
Q4 24
$228.5M
$55.6M
Q3 24
$237.1M
$56.2M
Q2 24
$264.3M
$51.5M
Q1 24
$266.7M
$51.3M
Total Assets
APLS
APLS
SKYT
SKYT
Q4 25
$1.1B
$733.9M
Q3 25
$1.1B
$787.0M
Q2 25
$821.4M
$334.7M
Q1 25
$807.3M
$326.8M
Q4 24
$885.1M
$311.8M
Q3 24
$901.9M
$315.1M
Q2 24
$904.5M
$290.4M
Q1 24
$831.9M
$312.3M
Debt / Equity
APLS
APLS
SKYT
SKYT
Q4 25
0.21×
Q3 25
0.21×
Q2 25
0.93×
Q1 25
0.72×
Q4 24
0.71×
Q3 24
0.73×
Q2 24
0.82×
Q1 24
0.35×
0.77×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APLS
APLS
SKYT
SKYT
Operating Cash FlowLast quarter
$-14.2M
$-36.1M
Free Cash FlowOCF − Capex
$-14.3M
$-42.2M
FCF MarginFCF / Revenue
-7.1%
-24.7%
Capex IntensityCapex / Revenue
0.1%
3.6%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$45.0M
$-53.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APLS
APLS
SKYT
SKYT
Q4 25
$-14.2M
$-36.1M
Q3 25
$108.5M
$-47.2M
Q2 25
$4.4M
$-1.7M
Q1 25
$-53.4M
$56.0M
Q4 24
$19.4M
$-1.3M
Q3 24
$34.1M
$14.3M
Q2 24
$-8.3M
$9.3M
Q1 24
$-133.0M
$-3.9M
Free Cash Flow
APLS
APLS
SKYT
SKYT
Q4 25
$-14.3M
$-42.2M
Q3 25
$108.3M
$-48.0M
Q2 25
$4.4M
$-4.3M
Q1 25
$-53.4M
$41.2M
Q4 24
$19.3M
$-2.0M
Q3 24
$9.1M
Q2 24
$-8.4M
$8.5M
Q1 24
$-133.3M
$-5.2M
FCF Margin
APLS
APLS
SKYT
SKYT
Q4 25
-7.1%
-24.7%
Q3 25
23.6%
-31.9%
Q2 25
2.5%
-7.3%
Q1 25
-32.0%
67.2%
Q4 24
9.1%
-2.6%
Q3 24
9.7%
Q2 24
-4.2%
9.1%
Q1 24
-77.3%
-6.5%
Capex Intensity
APLS
APLS
SKYT
SKYT
Q4 25
0.1%
3.6%
Q3 25
0.0%
0.6%
Q2 25
0.0%
4.5%
Q1 25
0.0%
24.1%
Q4 24
0.0%
0.9%
Q3 24
0.0%
5.5%
Q2 24
0.0%
0.9%
Q1 24
0.2%
1.6%
Cash Conversion
APLS
APLS
SKYT
SKYT
Q4 25
Q3 25
0.50×
-0.33×
Q2 25
Q1 25
Q4 24
Q3 24
9.47×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APLS
APLS

Syfovre$155.2M78%
Empaveli Pegcetacoplan$35.1M18%
Licensing And Other Revenue$9.6M5%

SKYT
SKYT

Advanced Technology Services Time And Materials And Cost Plus Fixed Fee Contracts$140.9M82%
Tool$28.9M17%
Overbilling Of ATS Development Revenues$2.0M1%

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