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Side-by-side financial comparison of Apellis Pharmaceuticals, Inc. (APLS) and Turning Point Brands, Inc. (TPB). Click either name above to swap in a different company.

Apellis Pharmaceuticals, Inc. is the larger business by last-quarter revenue ($199.9M vs $121.0M, roughly 1.7× Turning Point Brands, Inc.). Turning Point Brands, Inc. runs the higher net margin — 6.8% vs -29.5%, a 36.3% gap on every dollar of revenue. On growth, Turning Point Brands, Inc. posted the faster year-over-year revenue change (29.2% vs -5.9%). Turning Point Brands, Inc. produced more free cash flow last quarter ($21.5M vs $-14.3M). Over the past eight quarters, Turning Point Brands, Inc.'s revenue compounded faster (20.7% CAGR vs 7.7%).

Apellis Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing targeted therapies that modulate the complement system to address serious unmet medical needs. Its core products target ophthalmic conditions like geographic atrophy secondary to age-related macular degeneration, as well as rare hematological and autoimmune disorders, with primary operations in the United States and European markets.

Turning Point Australia (TPAUS) is a conservative lobby group based in Australia, affiliated with Turning Point USA but independent of it. Founded by Joel Jammal and first registered in 2023, the group has become active in trying to influence the outcome of the 2026 South Australian state election in March 2026.

APLS vs TPB — Head-to-Head

Bigger by revenue
APLS
APLS
1.7× larger
APLS
$199.9M
$121.0M
TPB
Growing faster (revenue YoY)
TPB
TPB
+35.1% gap
TPB
29.2%
-5.9%
APLS
Higher net margin
TPB
TPB
36.3% more per $
TPB
6.8%
-29.5%
APLS
More free cash flow
TPB
TPB
$35.8M more FCF
TPB
$21.5M
$-14.3M
APLS
Faster 2-yr revenue CAGR
TPB
TPB
Annualised
TPB
20.7%
7.7%
APLS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
APLS
APLS
TPB
TPB
Revenue
$199.9M
$121.0M
Net Profit
$-59.0M
$8.2M
Gross Margin
55.9%
Operating Margin
-25.6%
16.5%
Net Margin
-29.5%
6.8%
Revenue YoY
-5.9%
29.2%
Net Profit YoY
-62.2%
239.8%
EPS (diluted)
$-0.40
$0.40

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APLS
APLS
TPB
TPB
Q4 25
$199.9M
$121.0M
Q3 25
$458.6M
$119.0M
Q2 25
$178.5M
$116.6M
Q1 25
$166.8M
$106.4M
Q4 24
$212.5M
$93.7M
Q3 24
$196.8M
$90.7M
Q2 24
$199.7M
$93.2M
Q1 24
$172.3M
$83.1M
Net Profit
APLS
APLS
TPB
TPB
Q4 25
$-59.0M
$8.2M
Q3 25
$215.7M
$21.1M
Q2 25
$-42.2M
$14.5M
Q1 25
$-92.2M
$14.4M
Q4 24
$-36.4M
$2.4M
Q3 24
$-57.4M
$12.4M
Q2 24
$-37.7M
$13.0M
Q1 24
$-66.4M
$12.0M
Gross Margin
APLS
APLS
TPB
TPB
Q4 25
55.9%
Q3 25
59.2%
Q2 25
57.1%
Q1 25
56.0%
Q4 24
56.0%
Q3 24
55.6%
Q2 24
54.1%
Q1 24
58.2%
Operating Margin
APLS
APLS
TPB
TPB
Q4 25
-25.6%
16.5%
Q3 25
48.7%
21.8%
Q2 25
-18.6%
22.6%
Q1 25
-50.0%
21.8%
Q4 24
-12.3%
19.1%
Q3 24
-24.0%
22.9%
Q2 24
-14.7%
24.5%
Q1 24
-36.0%
23.2%
Net Margin
APLS
APLS
TPB
TPB
Q4 25
-29.5%
6.8%
Q3 25
47.0%
17.7%
Q2 25
-23.6%
12.4%
Q1 25
-55.3%
13.5%
Q4 24
-17.1%
2.6%
Q3 24
-29.2%
13.6%
Q2 24
-18.9%
14.0%
Q1 24
-38.5%
14.5%
EPS (diluted)
APLS
APLS
TPB
TPB
Q4 25
$-0.40
$0.40
Q3 25
$1.67
$1.13
Q2 25
$-0.33
$0.79
Q1 25
$-0.74
$0.79
Q4 24
$-0.30
$0.15
Q3 24
$-0.46
$0.68
Q2 24
$-0.30
$0.68
Q1 24
$-0.54
$0.63

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APLS
APLS
TPB
TPB
Cash + ST InvestmentsLiquidity on hand
$466.2M
$222.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$370.1M
$372.0M
Total Assets
$1.1B
$763.8M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APLS
APLS
TPB
TPB
Q4 25
$466.2M
$222.8M
Q3 25
$479.2M
$201.2M
Q2 25
$370.0M
$109.9M
Q1 25
$358.4M
$99.6M
Q4 24
$411.3M
$48.9M
Q3 24
$396.9M
$33.6M
Q2 24
$360.1M
$142.2M
Q1 24
$325.9M
$130.9M
Total Debt
APLS
APLS
TPB
TPB
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
$93.1M
Stockholders' Equity
APLS
APLS
TPB
TPB
Q4 25
$370.1M
$372.0M
Q3 25
$401.2M
$358.2M
Q2 25
$156.3M
$224.8M
Q1 25
$164.2M
$203.4M
Q4 24
$228.5M
$190.4M
Q3 24
$237.1M
$185.7M
Q2 24
$264.3M
$172.8M
Q1 24
$266.7M
$160.0M
Total Assets
APLS
APLS
TPB
TPB
Q4 25
$1.1B
$763.8M
Q3 25
$1.1B
$742.8M
Q2 25
$821.4M
$595.8M
Q1 25
$807.3M
$564.6M
Q4 24
$885.1M
$493.4M
Q3 24
$901.9M
$488.0M
Q2 24
$904.5M
$591.6M
Q1 24
$831.9M
$586.3M
Debt / Equity
APLS
APLS
TPB
TPB
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
0.35×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APLS
APLS
TPB
TPB
Operating Cash FlowLast quarter
$-14.2M
$24.9M
Free Cash FlowOCF − Capex
$-14.3M
$21.5M
FCF MarginFCF / Revenue
-7.1%
17.8%
Capex IntensityCapex / Revenue
0.1%
2.8%
Cash ConversionOCF / Net Profit
3.03×
TTM Free Cash FlowTrailing 4 quarters
$45.0M
$43.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APLS
APLS
TPB
TPB
Q4 25
$-14.2M
$24.9M
Q3 25
$108.5M
$3.3M
Q2 25
$4.4M
$11.8M
Q1 25
$-53.4M
$17.4M
Q4 24
$19.4M
$17.7M
Q3 24
$34.1M
$13.2M
Q2 24
$-8.3M
$13.4M
Q1 24
$-133.0M
$22.6M
Free Cash Flow
APLS
APLS
TPB
TPB
Q4 25
$-14.3M
$21.5M
Q3 25
$108.3M
$-721.0K
Q2 25
$4.4M
$7.8M
Q1 25
$-53.4M
$15.2M
Q4 24
$19.3M
$16.6M
Q3 24
$12.6M
Q2 24
$-8.4M
$10.9M
Q1 24
$-133.3M
$22.3M
FCF Margin
APLS
APLS
TPB
TPB
Q4 25
-7.1%
17.8%
Q3 25
23.6%
-0.6%
Q2 25
2.5%
6.7%
Q1 25
-32.0%
14.3%
Q4 24
9.1%
17.8%
Q3 24
13.9%
Q2 24
-4.2%
11.7%
Q1 24
-77.3%
26.8%
Capex Intensity
APLS
APLS
TPB
TPB
Q4 25
0.1%
2.8%
Q3 25
0.0%
3.4%
Q2 25
0.0%
3.4%
Q1 25
0.0%
2.1%
Q4 24
0.0%
1.2%
Q3 24
0.0%
0.7%
Q2 24
0.0%
2.7%
Q1 24
0.2%
0.4%
Cash Conversion
APLS
APLS
TPB
TPB
Q4 25
3.03×
Q3 25
0.50×
0.16×
Q2 25
0.82×
Q1 25
1.21×
Q4 24
7.34×
Q3 24
1.07×
Q2 24
1.03×
Q1 24
1.89×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APLS
APLS

Syfovre$155.2M78%
Empaveli Pegcetacoplan$35.1M18%
Licensing And Other Revenue$9.6M5%

TPB
TPB

US$111.5M92%
Non Us$9.6M8%

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