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Side-by-side financial comparison of Apellis Pharmaceuticals, Inc. (APLS) and WisdomTree, Inc. (WT). Click either name above to swap in a different company.

Apellis Pharmaceuticals, Inc. is the larger business by last-quarter revenue ($199.9M vs $147.4M, roughly 1.4× WisdomTree, Inc.). WisdomTree, Inc. runs the higher net margin — 27.1% vs -29.5%, a 56.6% gap on every dollar of revenue. On growth, WisdomTree, Inc. posted the faster year-over-year revenue change (33.2% vs -5.9%). WisdomTree, Inc. produced more free cash flow last quarter ($147.7M vs $-14.3M). Over the past eight quarters, WisdomTree, Inc.'s revenue compounded faster (23.4% CAGR vs 7.7%).

Apellis Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing targeted therapies that modulate the complement system to address serious unmet medical needs. Its core products target ophthalmic conditions like geographic atrophy secondary to age-related macular degeneration, as well as rare hematological and autoimmune disorders, with primary operations in the United States and European markets.

WisdomTree, Inc. is a global exchange-traded fund (ETF) and exchange-traded product (ETP) sponsor and asset manager with headquarters in New York. WisdomTree launched its first ETFs in June 2006, and became one of the major ETF providers in the United States. WisdomTree sponsors different ETFs that span asset classes and countries worldwide. Categories include: U.S. and International Equity, Currency, Fixed Income and Alternatives.

APLS vs WT — Head-to-Head

Bigger by revenue
APLS
APLS
1.4× larger
APLS
$199.9M
$147.4M
WT
Growing faster (revenue YoY)
WT
WT
+39.1% gap
WT
33.2%
-5.9%
APLS
Higher net margin
WT
WT
56.6% more per $
WT
27.1%
-29.5%
APLS
More free cash flow
WT
WT
$162.0M more FCF
WT
$147.7M
$-14.3M
APLS
Faster 2-yr revenue CAGR
WT
WT
Annualised
WT
23.4%
7.7%
APLS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
APLS
APLS
WT
WT
Revenue
$199.9M
$147.4M
Net Profit
$-59.0M
$40.0M
Gross Margin
Operating Margin
-25.6%
40.5%
Net Margin
-29.5%
27.1%
Revenue YoY
-5.9%
33.2%
Net Profit YoY
-62.2%
46.6%
EPS (diluted)
$-0.40
$0.28

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APLS
APLS
WT
WT
Q4 25
$199.9M
$147.4M
Q3 25
$458.6M
$125.6M
Q2 25
$178.5M
$112.6M
Q1 25
$166.8M
$108.1M
Q4 24
$212.5M
$110.7M
Q3 24
$196.8M
$113.2M
Q2 24
$199.7M
$107.0M
Q1 24
$172.3M
$96.8M
Net Profit
APLS
APLS
WT
WT
Q4 25
$-59.0M
$40.0M
Q3 25
$215.7M
$19.7M
Q2 25
$-42.2M
$24.8M
Q1 25
$-92.2M
$24.6M
Q4 24
$-36.4M
$27.3M
Q3 24
$-57.4M
$-4.5M
Q2 24
$-37.7M
$21.8M
Q1 24
$-66.4M
$22.1M
Operating Margin
APLS
APLS
WT
WT
Q4 25
-25.6%
40.5%
Q3 25
48.7%
36.3%
Q2 25
-18.6%
30.8%
Q1 25
-50.0%
31.6%
Q4 24
-12.3%
31.7%
Q3 24
-24.0%
36.0%
Q2 24
-14.7%
31.3%
Q1 24
-36.0%
28.9%
Net Margin
APLS
APLS
WT
WT
Q4 25
-29.5%
27.1%
Q3 25
47.0%
15.7%
Q2 25
-23.6%
22.0%
Q1 25
-55.3%
22.8%
Q4 24
-17.1%
24.7%
Q3 24
-29.2%
-4.0%
Q2 24
-18.9%
20.3%
Q1 24
-38.5%
22.8%
EPS (diluted)
APLS
APLS
WT
WT
Q4 25
$-0.40
$0.28
Q3 25
$1.67
$0.13
Q2 25
$-0.33
$0.17
Q1 25
$-0.74
$0.17
Q4 24
$-0.30
$0.20
Q3 24
$-0.46
$-0.13
Q2 24
$-0.30
$0.13
Q1 24
$-0.54
$0.13

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APLS
APLS
WT
WT
Cash + ST InvestmentsLiquidity on hand
$466.2M
Total DebtLower is stronger
Stockholders' EquityBook value
$370.1M
$413.7M
Total Assets
$1.1B
$1.5B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APLS
APLS
WT
WT
Q4 25
$466.2M
Q3 25
$479.2M
Q2 25
$370.0M
Q1 25
$358.4M
Q4 24
$411.3M
Q3 24
$396.9M
Q2 24
$360.1M
$132.5M
Q1 24
$325.9M
$116.9M
Total Debt
APLS
APLS
WT
WT
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
$93.1M
Stockholders' Equity
APLS
APLS
WT
WT
Q4 25
$370.1M
$413.7M
Q3 25
$401.2M
$373.4M
Q2 25
$156.3M
$445.1M
Q1 25
$164.2M
$415.6M
Q4 24
$228.5M
$400.0M
Q3 24
$237.1M
$374.9M
Q2 24
$264.3M
$445.6M
Q1 24
$266.7M
$423.2M
Total Assets
APLS
APLS
WT
WT
Q4 25
$1.1B
$1.5B
Q3 25
$1.1B
$1.4B
Q2 25
$821.4M
$1.1B
Q1 25
$807.3M
$1.0B
Q4 24
$885.1M
$1.0B
Q3 24
$901.9M
$1.0B
Q2 24
$904.5M
$964.1M
Q1 24
$831.9M
$931.7M
Debt / Equity
APLS
APLS
WT
WT
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
0.35×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APLS
APLS
WT
WT
Operating Cash FlowLast quarter
$-14.2M
$147.9M
Free Cash FlowOCF − Capex
$-14.3M
$147.7M
FCF MarginFCF / Revenue
-7.1%
100.2%
Capex IntensityCapex / Revenue
0.1%
0.1%
Cash ConversionOCF / Net Profit
3.70×
TTM Free Cash FlowTrailing 4 quarters
$45.0M
$240.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APLS
APLS
WT
WT
Q4 25
$-14.2M
$147.9M
Q3 25
$108.5M
$48.1M
Q2 25
$4.4M
$38.8M
Q1 25
$-53.4M
$6.4M
Q4 24
$19.4M
$113.5M
Q3 24
$34.1M
$47.7M
Q2 24
$-8.3M
$32.2M
Q1 24
$-133.0M
$-1.0M
Free Cash Flow
APLS
APLS
WT
WT
Q4 25
$-14.3M
$147.7M
Q3 25
$108.3M
$48.0M
Q2 25
$4.4M
$38.7M
Q1 25
$-53.4M
$6.3M
Q4 24
$19.3M
$113.3M
Q3 24
$47.7M
Q2 24
$-8.4M
$32.2M
Q1 24
$-133.3M
$-1.1M
FCF Margin
APLS
APLS
WT
WT
Q4 25
-7.1%
100.2%
Q3 25
23.6%
38.2%
Q2 25
2.5%
34.4%
Q1 25
-32.0%
5.9%
Q4 24
9.1%
102.4%
Q3 24
42.1%
Q2 24
-4.2%
30.1%
Q1 24
-77.3%
-1.1%
Capex Intensity
APLS
APLS
WT
WT
Q4 25
0.1%
0.1%
Q3 25
0.0%
0.0%
Q2 25
0.0%
0.1%
Q1 25
0.0%
0.0%
Q4 24
0.0%
0.1%
Q3 24
0.0%
0.0%
Q2 24
0.0%
0.0%
Q1 24
0.2%
0.1%
Cash Conversion
APLS
APLS
WT
WT
Q4 25
3.70×
Q3 25
0.50×
2.44×
Q2 25
1.57×
Q1 25
0.26×
Q4 24
4.15×
Q3 24
Q2 24
1.48×
Q1 24
-0.05×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APLS
APLS

Syfovre$155.2M78%
Empaveli Pegcetacoplan$35.1M18%
Licensing And Other Revenue$9.6M5%

WT
WT

Investment Advisory Management And Administrative Service$122.7M83%
Other Services Income$12.7M9%
IE$11.5M8%

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