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Side-by-side financial comparison of Applied Therapeutics, Inc. (APLT) and Rigetti Computing, Inc. (RGTI). Click either name above to swap in a different company.

Rigetti Computing, Inc. is the larger business by last-quarter revenue ($1.9M vs $1.0M, roughly 1.9× Applied Therapeutics, Inc.). Rigetti Computing, Inc. runs the higher net margin — -974.7% vs -1899.0%, a 924.3% gap on every dollar of revenue. On growth, Applied Therapeutics, Inc. posted the faster year-over-year revenue change (719.7% vs -17.9%).

Relief Therapeutics is a Swiss biopharmaceutical company based in Geneva. The company focuses on developing drugs for serious diseases with few or no existing treatment options. Its lead compound, RLF-100, is a synthetic form of a natural peptide that protects the lung. The company was incorporated as Relief Therapeutics Holdings AG (RFLB.S) and listed on the SIX Swiss Exchange in 2016.

Rigetti Computing, Inc. is a Berkeley, California-based developer of superconducting quantum integrated circuits used for quantum computers. Rigetti also develops a cloud platform called Forest that enables programmers to write quantum algorithms.

APLT vs RGTI — Head-to-Head

Bigger by revenue
RGTI
RGTI
1.9× larger
RGTI
$1.9M
$1.0M
APLT
Growing faster (revenue YoY)
APLT
APLT
+737.5% gap
APLT
719.7%
-17.9%
RGTI
Higher net margin
RGTI
RGTI
924.3% more per $
RGTI
-974.7%
-1899.0%
APLT

Income Statement — Q3 FY2025 vs Q4 FY2025

Metric
APLT
APLT
RGTI
RGTI
Revenue
$1.0M
$1.9M
Net Profit
$-19.0M
$-18.2M
Gross Margin
34.9%
Operating Margin
-1675.8%
-1209.7%
Net Margin
-1899.0%
-974.7%
Revenue YoY
719.7%
-17.9%
Net Profit YoY
72.3%
88.1%
EPS (diluted)
$-0.13
$-0.08

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
APLT
APLT
RGTI
RGTI
Q4 25
$1.9M
Q3 25
$1.0M
$1.9M
Q2 25
$0
$1.8M
Q1 25
$0
$1.5M
Q4 24
$-1.0K
$2.3M
Q3 24
$2.4M
Q2 24
$144.0K
$3.1M
Q1 24
$190.0K
$3.1M
Net Profit
APLT
APLT
RGTI
RGTI
Q4 25
$-18.2M
Q3 25
$-19.0M
$-201.0M
Q2 25
$-21.3M
$-39.7M
Q1 25
$-21.8M
$42.6M
Q4 24
$44.0M
$-153.0M
Q3 24
$-14.8M
Q2 24
$2.9M
$-12.4M
Q1 24
$-83.9M
$-20.8M
Gross Margin
APLT
APLT
RGTI
RGTI
Q4 25
34.9%
Q3 25
20.7%
Q2 25
31.4%
Q1 25
30.0%
Q4 24
44.1%
Q3 24
50.6%
Q2 24
64.5%
Q1 24
49.1%
Operating Margin
APLT
APLT
RGTI
RGTI
Q4 25
-1209.7%
Q3 25
-1675.8%
-1055.4%
Q2 25
-1103.9%
Q1 25
-1469.6%
Q4 24
3302300.0%
-813.3%
Q3 24
-729.4%
Q2 24
-14194.4%
-521.2%
Q1 24
-11101.6%
-543.4%
Net Margin
APLT
APLT
RGTI
RGTI
Q4 25
-974.7%
Q3 25
-1899.0%
-10321.9%
Q2 25
-2201.8%
Q1 25
2895.3%
Q4 24
-4400700.0%
-6726.5%
Q3 24
-623.8%
Q2 24
2012.5%
-402.5%
Q1 24
-44177.9%
-680.6%
EPS (diluted)
APLT
APLT
RGTI
RGTI
Q4 25
$-0.08
Q3 25
$-0.13
$-0.62
Q2 25
$-0.15
$-0.13
Q1 25
$-0.15
$0.13
Q4 24
$0.52
$-0.80
Q3 24
$-0.08
Q2 24
$-0.13
$-0.07
Q1 24
$-0.67
$-0.14

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
APLT
APLT
RGTI
RGTI
Cash + ST InvestmentsLiquidity on hand
$11.9M
$44.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$-561.0K
$546.2M
Total Assets
$34.4M
$666.6M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
APLT
APLT
RGTI
RGTI
Q4 25
$44.9M
Q3 25
$11.9M
$26.1M
Q2 25
$30.4M
$57.2M
Q1 25
$50.8M
$37.2M
Q4 24
$79.4M
$67.7M
Q3 24
$20.3M
Q2 24
$122.2M
$20.7M
Q1 24
$146.5M
$35.1M
Stockholders' Equity
APLT
APLT
RGTI
RGTI
Q4 25
$546.2M
Q3 25
$-561.0K
$371.8M
Q2 25
$17.4M
$553.3M
Q1 25
$36.7M
$207.1M
Q4 24
$57.0M
$126.6M
Q3 24
$122.8M
Q2 24
$72.4M
$122.2M
Q1 24
$67.3M
$115.6M
Total Assets
APLT
APLT
RGTI
RGTI
Q4 25
$666.6M
Q3 25
$34.4M
$630.3M
Q2 25
$37.3M
$636.7M
Q1 25
$56.9M
$269.1M
Q4 24
$86.7M
$284.8M
Q3 24
$157.3M
Q2 24
$127.8M
$162.4M
Q1 24
$151.2M
$162.1M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
APLT
APLT
RGTI
RGTI
Operating Cash FlowLast quarter
$-18.4M
$-14.9M
Free Cash FlowOCF − Capex
$-19.5M
FCF MarginFCF / Revenue
-1042.5%
Capex IntensityCapex / Revenue
244.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-77.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
APLT
APLT
RGTI
RGTI
Q4 25
$-14.9M
Q3 25
$-18.4M
$-13.8M
Q2 25
$-20.3M
$-16.2M
Q1 25
$-28.6M
$-13.7M
Q4 24
$-19.5M
$-8.5M
Q3 24
$-15.4M
Q2 24
$-22.6M
$-13.5M
Q1 24
$-18.9M
$-13.1M
Free Cash Flow
APLT
APLT
RGTI
RGTI
Q4 25
$-19.5M
Q3 25
$-19.7M
Q2 25
$-21.8M
Q1 25
$-16.2M
Q4 24
$-9.8M
Q3 24
$-17.7M
Q2 24
$-15.6M
Q1 24
$-18.6M
FCF Margin
APLT
APLT
RGTI
RGTI
Q4 25
-1042.5%
Q3 25
-1012.4%
Q2 25
-1212.4%
Q1 25
-1100.4%
Q4 24
-432.1%
Q3 24
-744.5%
Q2 24
-504.3%
Q1 24
-610.5%
Capex Intensity
APLT
APLT
RGTI
RGTI
Q4 25
244.8%
Q3 25
302.5%
Q2 25
314.7%
Q1 25
173.0%
Q4 24
56.4%
Q3 24
95.8%
Q2 24
66.3%
Q1 24
180.0%
Cash Conversion
APLT
APLT
RGTI
RGTI
Q4 25
Q3 25
Q2 25
Q1 25
-0.32×
Q4 24
-0.44×
Q3 24
Q2 24
-7.80×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

APLT
APLT

Segment breakdown not available.

RGTI
RGTI

Collaborative Research And Other Professional Services$1.7M93%
Other$131.0K7%

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