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Side-by-side financial comparison of ARDELYX, INC. (ARDX) and SEMrush Holdings, Inc. (SEMR). Click either name above to swap in a different company.
SEMrush Holdings, Inc. is the larger business by last-quarter revenue ($117.7M vs $94.5M, roughly 1.2× ARDELYX, INC.). SEMrush Holdings, Inc. runs the higher net margin — -9.4% vs -39.8%, a 30.4% gap on every dollar of revenue. On growth, ARDELYX, INC. posted the faster year-over-year revenue change (27.5% vs 14.6%). Over the past eight quarters, SEMrush Holdings, Inc.'s revenue compounded faster (17.1% CAGR vs 13.6%).
Ardelyx, Inc. is a commercial-stage biopharmaceutical firm developing and commercializing innovative therapies for gastrointestinal, cardiorenal and metabolic diseases with high unmet medical needs. Its lead product is approved in the US for irritable bowel syndrome with constipation, and it holds a robust pipeline of early and late-stage drug candidates.
Semrush Holdings, Inc. is an American public company that has a SaaS platform known as Semrush. The platform is used for keyword research, competitive analysis, site audits, backlink tracking, domain authority tracking, and online visibility insights. The keyword research tool provides various data points on each keyword. The platform also collects information about online keywords gathered from Google and Bing search engines. It was released by Boston-based company Semrush Inc, founded by Ol...
ARDX vs SEMR — Head-to-Head
Income Statement — Q1 FY2026 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $94.5M | $117.7M |
| Net Profit | $-37.6M | $-11.1M |
| Gross Margin | — | 80.4% |
| Operating Margin | — | -11.8% |
| Net Margin | -39.8% | -9.4% |
| Revenue YoY | 27.5% | 14.6% |
| Net Profit YoY | — | -431.8% |
| EPS (diluted) | $-0.15 | $-0.09 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | $94.5M | — | ||
| Q4 25 | $125.2M | $117.7M | ||
| Q3 25 | $110.3M | $112.1M | ||
| Q2 25 | $97.7M | $108.9M | ||
| Q1 25 | $74.1M | $105.0M | ||
| Q4 24 | $116.1M | $102.6M | ||
| Q3 24 | $98.2M | $97.4M | ||
| Q2 24 | $73.2M | $91.0M |
| Q1 26 | $-37.6M | — | ||
| Q4 25 | $-407.0K | $-11.1M | ||
| Q3 25 | $-969.0K | $-2.1M | ||
| Q2 25 | $-19.1M | $-6.6M | ||
| Q1 25 | $-41.1M | $849.0K | ||
| Q4 24 | $4.6M | $3.3M | ||
| Q3 24 | $-809.0K | $1.1M | ||
| Q2 24 | $-16.5M | $1.7M |
| Q1 26 | — | — | ||
| Q4 25 | 91.3% | 80.4% | ||
| Q3 25 | 96.4% | 80.2% | ||
| Q2 25 | 87.3% | 80.6% | ||
| Q1 25 | 83.4% | 81.1% | ||
| Q4 24 | 84.3% | 81.7% | ||
| Q3 24 | 84.0% | 82.5% | ||
| Q2 24 | 87.1% | 83.6% |
| Q1 26 | — | — | ||
| Q4 25 | 4.1% | -11.8% | ||
| Q3 25 | 4.2% | -4.0% | ||
| Q2 25 | -14.7% | -4.0% | ||
| Q1 25 | -49.0% | -0.1% | ||
| Q4 24 | 7.0% | 1.7% | ||
| Q3 24 | 2.3% | 1.8% | ||
| Q2 24 | -18.6% | 3.7% |
| Q1 26 | -39.8% | — | ||
| Q4 25 | -0.3% | -9.4% | ||
| Q3 25 | -0.9% | -1.9% | ||
| Q2 25 | -19.5% | -6.0% | ||
| Q1 25 | -55.5% | 0.8% | ||
| Q4 24 | 4.0% | 3.3% | ||
| Q3 24 | -0.8% | 1.1% | ||
| Q2 24 | -22.5% | 1.8% |
| Q1 26 | $-0.15 | — | ||
| Q4 25 | $-0.01 | $-0.09 | ||
| Q3 25 | $0.00 | $-0.01 | ||
| Q2 25 | $-0.08 | $-0.04 | ||
| Q1 25 | $-0.17 | $0.01 | ||
| Q4 24 | $0.01 | $0.03 | ||
| Q3 24 | $0.00 | $0.01 | ||
| Q2 24 | $-0.07 | $0.01 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $238.1M | $264.3M |
| Total DebtLower is stronger | $203.5M | — |
| Stockholders' EquityBook value | $148.6M | $288.6M |
| Total Assets | $504.5M | $454.1M |
| Debt / EquityLower = less leverage | 1.37× | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | $238.1M | — | ||
| Q4 25 | $68.0M | $264.3M | ||
| Q3 25 | $42.7M | $80.8M | ||
| Q2 25 | $90.0M | $54.3M | ||
| Q1 25 | $30.8M | $64.7M | ||
| Q4 24 | $64.9M | $48.9M | ||
| Q3 24 | $47.4M | $45.1M | ||
| Q2 24 | $41.9M | $69.6M |
| Q1 26 | $203.5M | — | ||
| Q4 25 | $202.8M | — | ||
| Q3 25 | $202.1M | — | ||
| Q2 25 | $201.4M | — | ||
| Q1 25 | $151.3M | — | ||
| Q4 24 | $150.9M | — | ||
| Q3 24 | $100.7M | — | ||
| Q2 24 | $100.2M | — |
| Q1 26 | $148.6M | — | ||
| Q4 25 | $166.9M | $288.6M | ||
| Q3 25 | $154.3M | $289.7M | ||
| Q2 25 | $139.5M | $279.0M | ||
| Q1 25 | $145.7M | $268.7M | ||
| Q4 24 | $173.3M | $256.6M | ||
| Q3 24 | $158.3M | $248.5M | ||
| Q2 24 | $147.0M | $235.6M |
| Q1 26 | $504.5M | — | ||
| Q4 25 | $501.6M | $454.1M | ||
| Q3 25 | $486.2M | $450.4M | ||
| Q2 25 | $466.8M | $424.9M | ||
| Q1 25 | $410.2M | $416.5M | ||
| Q4 24 | $435.8M | $390.9M | ||
| Q3 24 | $367.9M | $383.8M | ||
| Q2 24 | $343.5M | $372.9M |
| Q1 26 | 1.37× | — | ||
| Q4 25 | 1.21× | — | ||
| Q3 25 | 1.31× | — | ||
| Q2 25 | 1.44× | — | ||
| Q1 25 | 1.04× | — | ||
| Q4 24 | 0.87× | — | ||
| Q3 24 | 0.64× | — | ||
| Q2 24 | 0.68× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | — | $14.9M |
| Free Cash FlowOCF − Capex | — | $14.8M |
| FCF MarginFCF / Revenue | — | 12.6% |
| Capex IntensityCapex / Revenue | — | 0.1% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | — | $57.8M |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $21.0M | $14.9M | ||
| Q3 25 | $365.0K | $21.9M | ||
| Q2 25 | $-25.3M | $684.0K | ||
| Q1 25 | $-38.5M | $22.1M | ||
| Q4 24 | $9.8M | $11.9M | ||
| Q3 24 | $501.0K | $8.1M | ||
| Q2 24 | $-19.4M | $12.1M |
| Q1 26 | — | — | ||
| Q4 25 | $20.6M | $14.8M | ||
| Q3 25 | $209.0K | $21.5M | ||
| Q2 25 | $-26.0M | $80.0K | ||
| Q1 25 | $-38.8M | $21.4M | ||
| Q4 24 | $9.2M | $11.5M | ||
| Q3 24 | $364.0K | $7.6M | ||
| Q2 24 | $-19.5M | $10.0M |
| Q1 26 | — | — | ||
| Q4 25 | 16.4% | 12.6% | ||
| Q3 25 | 0.2% | 19.2% | ||
| Q2 25 | -26.6% | 0.1% | ||
| Q1 25 | -52.3% | 20.4% | ||
| Q4 24 | 7.9% | 11.2% | ||
| Q3 24 | 0.4% | 7.8% | ||
| Q2 24 | -26.7% | 11.0% |
| Q1 26 | — | — | ||
| Q4 25 | 0.3% | 0.1% | ||
| Q3 25 | 0.1% | 0.4% | ||
| Q2 25 | 0.7% | 0.6% | ||
| Q1 25 | 0.4% | 0.7% | ||
| Q4 24 | 0.5% | 0.4% | ||
| Q3 24 | 0.1% | 0.5% | ||
| Q2 24 | 0.2% | 2.4% |
| Q1 26 | — | — | ||
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | 26.04× | ||
| Q4 24 | 2.11× | 3.57× | ||
| Q3 24 | — | 7.44× | ||
| Q2 24 | — | 7.32× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
ARDX
| IBSRELA | $70.1M | 74% |
| XPHOZAH | $23.3M | 25% |
| Non-cash royalty revenue related to the sale of future royalties | $695.0K | 1% |
| Product supply revenue | $354.0K | 0% |
SEMR
Segment breakdown not available.
