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Side-by-side financial comparison of ARDELYX, INC. (ARDX) and SOUTHERN MISSOURI BANCORP, INC. (SMBC). Click either name above to swap in a different company.
ARDELYX, INC. is the larger business by last-quarter revenue ($94.5M vs $49.6M, roughly 1.9× SOUTHERN MISSOURI BANCORP, INC.). SOUTHERN MISSOURI BANCORP, INC. runs the higher net margin — 36.6% vs -39.8%, a 76.4% gap on every dollar of revenue. On growth, ARDELYX, INC. posted the faster year-over-year revenue change (27.5% vs 10.3%). Over the past eight quarters, ARDELYX, INC.'s revenue compounded faster (13.6% CAGR vs 11.3%).
Ardelyx, Inc. is a commercial-stage biopharmaceutical firm developing and commercializing innovative therapies for gastrointestinal, cardiorenal and metabolic diseases with high unmet medical needs. Its lead product is approved in the US for irritable bowel syndrome with constipation, and it holds a robust pipeline of early and late-stage drug candidates.
U.S. Bancorp is an American multinational banking institution headquartered in Minneapolis, Minnesota and incorporated in Delaware. It is the 5th-largest bank in the United States as of 2025. As the largest bank in the Midwestern United States, it is considered systemically important by the Financial Stability Board. It is the parent company of its primary operating entity, U.S. Bank National Association, which does business as U.S. Bank. The company provides banking, investment, mortgage, tr...
ARDX vs SMBC — Head-to-Head
Income Statement — Q1 FY2026 vs Q2 FY2026
| Metric | | |
|---|---|---|
| Revenue | $94.5M | $49.6M |
| Net Profit | $-37.6M | $18.1M |
| Gross Margin | — | — |
| Operating Margin | — | 45.7% |
| Net Margin | -39.8% | 36.6% |
| Revenue YoY | 27.5% | 10.3% |
| Net Profit YoY | — | 23.9% |
| EPS (diluted) | $-0.15 | $1.62 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | $94.5M | — | ||
| Q4 25 | $125.2M | $49.6M | ||
| Q3 25 | $110.3M | $49.0M | ||
| Q2 25 | $97.7M | $47.6M | ||
| Q1 25 | $74.1M | $46.1M | ||
| Q4 24 | $116.1M | $45.0M | ||
| Q3 24 | $98.2M | $43.8M | ||
| Q2 24 | $73.2M | $42.9M |
| Q1 26 | $-37.6M | — | ||
| Q4 25 | $-407.0K | $18.1M | ||
| Q3 25 | $-969.0K | $15.7M | ||
| Q2 25 | $-19.1M | $15.8M | ||
| Q1 25 | $-41.1M | $15.7M | ||
| Q4 24 | $4.6M | $14.7M | ||
| Q3 24 | $-809.0K | $12.5M | ||
| Q2 24 | $-16.5M | $13.5M |
| Q1 26 | — | — | ||
| Q4 25 | 91.3% | — | ||
| Q3 25 | 96.4% | — | ||
| Q2 25 | 87.3% | — | ||
| Q1 25 | 83.4% | — | ||
| Q4 24 | 84.3% | — | ||
| Q3 24 | 84.0% | — | ||
| Q2 24 | 87.1% | — |
| Q1 26 | — | — | ||
| Q4 25 | 4.1% | 45.7% | ||
| Q3 25 | 4.2% | 39.7% | ||
| Q2 25 | -14.7% | 40.2% | ||
| Q1 25 | -49.0% | 43.0% | ||
| Q4 24 | 7.0% | 42.7% | ||
| Q3 24 | 2.3% | 36.1% | ||
| Q2 24 | -18.6% | 39.6% |
| Q1 26 | -39.8% | — | ||
| Q4 25 | -0.3% | 36.6% | ||
| Q3 25 | -0.9% | 31.9% | ||
| Q2 25 | -19.5% | 33.2% | ||
| Q1 25 | -55.5% | 34.0% | ||
| Q4 24 | 4.0% | 32.6% | ||
| Q3 24 | -0.8% | 28.4% | ||
| Q2 24 | -22.5% | 31.6% |
| Q1 26 | $-0.15 | — | ||
| Q4 25 | $-0.01 | $1.62 | ||
| Q3 25 | $0.00 | $1.38 | ||
| Q2 25 | $-0.08 | $1.39 | ||
| Q1 25 | $-0.17 | $1.39 | ||
| Q4 24 | $0.01 | $1.30 | ||
| Q3 24 | $0.00 | $1.10 | ||
| Q2 24 | $-0.07 | $1.20 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $238.1M | $134.1M |
| Total DebtLower is stronger | $203.5M | — |
| Stockholders' EquityBook value | $148.6M | $567.4M |
| Total Assets | $504.5M | $5.1B |
| Debt / EquityLower = less leverage | 1.37× | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | $238.1M | — | ||
| Q4 25 | $68.0M | $134.1M | ||
| Q3 25 | $42.7M | $124.1M | ||
| Q2 25 | $90.0M | $192.9M | ||
| Q1 25 | $30.8M | $226.9M | ||
| Q4 24 | $64.9M | $145.8M | ||
| Q3 24 | $47.4M | $75.3M | ||
| Q2 24 | $41.9M | $60.9M |
| Q1 26 | $203.5M | — | ||
| Q4 25 | $202.8M | — | ||
| Q3 25 | $202.1M | — | ||
| Q2 25 | $201.4M | — | ||
| Q1 25 | $151.3M | — | ||
| Q4 24 | $150.9M | — | ||
| Q3 24 | $100.7M | — | ||
| Q2 24 | $100.2M | — |
| Q1 26 | $148.6M | — | ||
| Q4 25 | $166.9M | $567.4M | ||
| Q3 25 | $154.3M | $560.2M | ||
| Q2 25 | $139.5M | $544.7M | ||
| Q1 25 | $145.7M | $528.8M | ||
| Q4 24 | $173.3M | $512.4M | ||
| Q3 24 | $158.3M | $505.6M | ||
| Q2 24 | $147.0M | $488.7M |
| Q1 26 | $504.5M | — | ||
| Q4 25 | $501.6M | $5.1B | ||
| Q3 25 | $486.2M | $5.0B | ||
| Q2 25 | $466.8M | $5.0B | ||
| Q1 25 | $410.2M | $5.0B | ||
| Q4 24 | $435.8M | $4.9B | ||
| Q3 24 | $367.9M | $4.7B | ||
| Q2 24 | $343.5M | $4.6B |
| Q1 26 | 1.37× | — | ||
| Q4 25 | 1.21× | — | ||
| Q3 25 | 1.31× | — | ||
| Q2 25 | 1.44× | — | ||
| Q1 25 | 1.04× | — | ||
| Q4 24 | 0.87× | — | ||
| Q3 24 | 0.64× | — | ||
| Q2 24 | 0.68× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | — | $21.3M |
| Free Cash FlowOCF − Capex | — | $20.2M |
| FCF MarginFCF / Revenue | — | 40.6% |
| Capex IntensityCapex / Revenue | — | 2.2% |
| Cash ConversionOCF / Net Profit | — | 1.17× |
| TTM Free Cash FlowTrailing 4 quarters | — | $133.6M |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $21.0M | $21.3M | ||
| Q3 25 | $365.0K | $16.3M | ||
| Q2 25 | $-25.3M | $81.6M | ||
| Q1 25 | $-38.5M | $24.1M | ||
| Q4 24 | $9.8M | $20.1M | ||
| Q3 24 | $501.0K | $10.0M | ||
| Q2 24 | $-19.4M | $70.3M |
| Q1 26 | — | — | ||
| Q4 25 | $20.6M | $20.2M | ||
| Q3 25 | $209.0K | $15.4M | ||
| Q2 25 | $-26.0M | $75.3M | ||
| Q1 25 | $-38.8M | $22.7M | ||
| Q4 24 | $9.2M | $18.2M | ||
| Q3 24 | $364.0K | $8.6M | ||
| Q2 24 | $-19.5M | $61.2M |
| Q1 26 | — | — | ||
| Q4 25 | 16.4% | 40.6% | ||
| Q3 25 | 0.2% | 31.4% | ||
| Q2 25 | -26.6% | 158.1% | ||
| Q1 25 | -52.3% | 49.3% | ||
| Q4 24 | 7.9% | 40.3% | ||
| Q3 24 | 0.4% | 19.5% | ||
| Q2 24 | -26.7% | 142.8% |
| Q1 26 | — | — | ||
| Q4 25 | 0.3% | 2.2% | ||
| Q3 25 | 0.1% | 1.8% | ||
| Q2 25 | 0.7% | 13.2% | ||
| Q1 25 | 0.4% | 3.0% | ||
| Q4 24 | 0.5% | 4.4% | ||
| Q3 24 | 0.1% | 3.3% | ||
| Q2 24 | 0.2% | 21.1% |
| Q1 26 | — | — | ||
| Q4 25 | — | 1.17× | ||
| Q3 25 | — | 1.04× | ||
| Q2 25 | — | 5.17× | ||
| Q1 25 | — | 1.54× | ||
| Q4 24 | 2.11× | 1.37× | ||
| Q3 24 | — | 0.80× | ||
| Q2 24 | — | 5.19× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
ARDX
| IBSRELA | $70.1M | 74% |
| XPHOZAH | $23.3M | 25% |
| Non-cash royalty revenue related to the sale of future royalties | $695.0K | 1% |
| Product supply revenue | $354.0K | 0% |
SMBC
Segment breakdown not available.
