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Side-by-side financial comparison of ARROWHEAD PHARMACEUTICALS, INC. (ARWR) and Empire State Realty Trust, Inc. (ESRT). Click either name above to swap in a different company.

ARROWHEAD PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($264.0M vs $190.3M, roughly 1.4× Empire State Realty Trust, Inc.). ARROWHEAD PHARMACEUTICALS, INC. runs the higher net margin — 11.7% vs 1.6%, a 10.1% gap on every dollar of revenue. On growth, ARROWHEAD PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (10461.3% vs 5.7%).

Arrowhead Pharmaceuticals, Inc. is a publicly traded biopharmaceutical company based in Pasadena, California. Arrowhead's products in development act through RNA interference (RNAi) mechanisms of action. The company focuses on treatments for hepatitis B, liver disease associated with alpha 1-antitrypsin deficiency and cardiovascular disease.

Empire State Realty Trust is a leading real estate investment trust that owns, manages, and operates a portfolio of premium commercial, residential, and retail properties primarily in the New York City metropolitan area, including the iconic Empire State Building. It serves corporate tenants, retail partners, and residential occupants, focusing on sustainable property operations and long-term asset value growth.

ARWR vs ESRT — Head-to-Head

Bigger by revenue
ARWR
ARWR
1.4× larger
ARWR
$264.0M
$190.3M
ESRT
Growing faster (revenue YoY)
ARWR
ARWR
+10455.6% gap
ARWR
10461.3%
5.7%
ESRT
Higher net margin
ARWR
ARWR
10.1% more per $
ARWR
11.7%
1.6%
ESRT

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
ARWR
ARWR
ESRT
ESRT
Revenue
$264.0M
$190.3M
Net Profit
$30.8M
$3.0M
Gross Margin
Operating Margin
15.5%
15.5%
Net Margin
11.7%
1.6%
Revenue YoY
10461.3%
5.7%
Net Profit YoY
117.8%
-73.7%
EPS (diluted)
$0.22
$0.20

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ARWR
ARWR
ESRT
ESRT
Q1 26
$190.3M
Q4 25
$264.0M
$199.2M
Q3 25
$197.7M
Q2 25
$191.3M
Q1 25
$180.1M
Q4 24
$197.6M
Q3 24
$199.6M
Q2 24
$189.5M
Net Profit
ARWR
ARWR
ESRT
ESRT
Q1 26
$3.0M
Q4 25
$30.8M
$32.2M
Q3 25
$13.6M
Q2 25
$11.4M
Q1 25
$15.8M
Q4 24
$18.8M
Q3 24
$22.8M
Q2 24
$28.6M
Operating Margin
ARWR
ARWR
ESRT
ESRT
Q1 26
15.5%
Q4 25
15.5%
17.8%
Q3 25
19.9%
Q2 25
18.4%
Q1 25
14.3%
Q4 24
21.7%
Q3 24
22.7%
Q2 24
20.8%
Net Margin
ARWR
ARWR
ESRT
ESRT
Q1 26
1.6%
Q4 25
11.7%
16.1%
Q3 25
6.9%
Q2 25
6.0%
Q1 25
8.8%
Q4 24
9.5%
Q3 24
11.4%
Q2 24
15.1%
EPS (diluted)
ARWR
ARWR
ESRT
ESRT
Q1 26
$0.20
Q4 25
$0.22
$0.11
Q3 25
$0.05
Q2 25
$0.04
Q1 25
$0.05
Q4 24
$0.07
Q3 24
$0.08
Q2 24
$0.10

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ARWR
ARWR
ESRT
ESRT
Cash + ST InvestmentsLiquidity on hand
$715.0M
$68.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$568.4M
$1.8B
Total Assets
$1.6B
$4.4B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ARWR
ARWR
ESRT
ESRT
Q1 26
$68.8M
Q4 25
$715.0M
$132.7M
Q3 25
$154.1M
Q2 25
$94.6M
Q1 25
$187.8M
Q4 24
$385.5M
Q3 24
$421.9M
Q2 24
$535.5M
Stockholders' Equity
ARWR
ARWR
ESRT
ESRT
Q1 26
$1.8B
Q4 25
$568.4M
$1.1B
Q3 25
$1.0B
Q2 25
$1.0B
Q1 25
$1.0B
Q4 24
$1.0B
Q3 24
$1.0B
Q2 24
$1.0B
Total Assets
ARWR
ARWR
ESRT
ESRT
Q1 26
$4.4B
Q4 25
$1.6B
$4.5B
Q3 25
$4.1B
Q2 25
$4.1B
Q1 25
$4.1B
Q4 24
$4.5B
Q3 24
$4.4B
Q2 24
$4.4B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ARWR
ARWR
ESRT
ESRT
Operating Cash FlowLast quarter
$13.5M
Free Cash FlowOCF − Capex
$11.3M
FCF MarginFCF / Revenue
4.3%
Capex IntensityCapex / Revenue
0.8%
10.0%
Cash ConversionOCF / Net Profit
0.44×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ARWR
ARWR
ESRT
ESRT
Q1 26
Q4 25
$13.5M
$249.1M
Q3 25
$105.3M
Q2 25
$26.7M
Q1 25
$83.1M
Q4 24
$260.9M
Q3 24
$102.8M
Q2 24
$37.1M
Free Cash Flow
ARWR
ARWR
ESRT
ESRT
Q1 26
Q4 25
$11.3M
$50.6M
Q3 25
$72.8M
Q2 25
$-55.1M
Q1 25
$41.1M
Q4 24
$88.0M
Q3 24
$-65.1M
Q2 24
$19.5M
FCF Margin
ARWR
ARWR
ESRT
ESRT
Q1 26
Q4 25
4.3%
25.4%
Q3 25
36.8%
Q2 25
-28.8%
Q1 25
22.8%
Q4 24
44.5%
Q3 24
-32.6%
Q2 24
10.3%
Capex Intensity
ARWR
ARWR
ESRT
ESRT
Q1 26
10.0%
Q4 25
0.8%
99.6%
Q3 25
16.5%
Q2 25
42.8%
Q1 25
23.4%
Q4 24
87.5%
Q3 24
84.1%
Q2 24
9.3%
Cash Conversion
ARWR
ARWR
ESRT
ESRT
Q1 26
Q4 25
0.44×
7.74×
Q3 25
7.72×
Q2 25
2.35×
Q1 25
5.27×
Q4 24
13.88×
Q3 24
4.51×
Q2 24
1.30×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ARWR
ARWR

Segment breakdown not available.

ESRT
ESRT

Rental revenue (1)$166.1M87%
Observatory revenue$18.5M10%
Other revenue and fees$4.1M2%
Lease termination fees$1.4M1%
Third-party management and other fees$277.0K0%

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