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Side-by-side financial comparison of ARROWHEAD PHARMACEUTICALS, INC. (ARWR) and Five9, Inc. (FIVN). Click either name above to swap in a different company.

Five9, Inc. is the larger business by last-quarter revenue ($300.3M vs $264.0M, roughly 1.1× ARROWHEAD PHARMACEUTICALS, INC.). On growth, ARROWHEAD PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (10461.3% vs 7.8%). Five9, Inc. produced more free cash flow last quarter ($77.3M vs $11.3M).

Arrowhead Pharmaceuticals, Inc. is a publicly traded biopharmaceutical company based in Pasadena, California. Arrowhead's products in development act through RNA interference (RNAi) mechanisms of action. The company focuses on treatments for hepatitis B, liver disease associated with alpha 1-antitrypsin deficiency and cardiovascular disease.

Five9, Inc. is a leading global provider of cloud-native contact center software and solutions. It serves enterprises of all sizes across retail, healthcare, financial services, and technology sectors, offering omnichannel customer engagement tools, AI-powered automation, workforce management, and analytics to boost customer experience and operational efficiency.

ARWR vs FIVN — Head-to-Head

Bigger by revenue
FIVN
FIVN
1.1× larger
FIVN
$300.3M
$264.0M
ARWR
Growing faster (revenue YoY)
ARWR
ARWR
+10453.6% gap
ARWR
10461.3%
7.8%
FIVN
More free cash flow
FIVN
FIVN
$66.0M more FCF
FIVN
$77.3M
$11.3M
ARWR

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
ARWR
ARWR
FIVN
FIVN
Revenue
$264.0M
$300.3M
Net Profit
$30.8M
Gross Margin
55.4%
Operating Margin
15.5%
6.6%
Net Margin
11.7%
Revenue YoY
10461.3%
7.8%
Net Profit YoY
117.8%
EPS (diluted)
$0.22
$0.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ARWR
ARWR
FIVN
FIVN
Q4 25
$264.0M
$300.3M
Q3 25
$285.8M
Q2 25
$283.3M
Q1 25
$279.7M
Q4 24
$278.7M
Q3 24
$264.2M
Q2 24
$252.1M
Q1 24
$247.0M
Net Profit
ARWR
ARWR
FIVN
FIVN
Q4 25
$30.8M
Q3 25
$18.0M
Q2 25
$1.2M
Q1 25
$576.0K
Q4 24
Q3 24
$-4.5M
Q2 24
$-12.8M
Q1 24
$-7.1M
Gross Margin
ARWR
ARWR
FIVN
FIVN
Q4 25
55.4%
Q3 25
55.0%
Q2 25
54.9%
Q1 25
55.0%
Q4 24
56.0%
Q3 24
53.8%
Q2 24
53.0%
Q1 24
53.6%
Operating Margin
ARWR
ARWR
FIVN
FIVN
Q4 25
15.5%
6.6%
Q3 25
5.6%
Q2 25
-0.6%
Q1 25
-1.9%
Q4 24
1.5%
Q3 24
-5.8%
Q2 24
-7.7%
Q1 24
-8.4%
Net Margin
ARWR
ARWR
FIVN
FIVN
Q4 25
11.7%
Q3 25
6.3%
Q2 25
0.4%
Q1 25
0.2%
Q4 24
Q3 24
-1.7%
Q2 24
-5.1%
Q1 24
-2.9%
EPS (diluted)
ARWR
ARWR
FIVN
FIVN
Q4 25
$0.22
$0.22
Q3 25
$0.21
Q2 25
$0.01
Q1 25
$0.01
Q4 24
$0.16
Q3 24
$-0.06
Q2 24
$-0.17
Q1 24
$-0.10

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ARWR
ARWR
FIVN
FIVN
Cash + ST InvestmentsLiquidity on hand
$715.0M
$232.1M
Total DebtLower is stronger
Stockholders' EquityBook value
$568.4M
$785.8M
Total Assets
$1.6B
$1.8B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ARWR
ARWR
FIVN
FIVN
Q4 25
$715.0M
$232.1M
Q3 25
$193.4M
Q2 25
$205.5M
Q1 25
$370.3M
Q4 24
$362.5M
Q3 24
$291.0M
Q2 24
$175.7M
Q1 24
$240.2M
Stockholders' Equity
ARWR
ARWR
FIVN
FIVN
Q4 25
$568.4M
$785.8M
Q3 25
$775.3M
Q2 25
$717.4M
Q1 25
$664.3M
Q4 24
$622.2M
Q3 24
$565.6M
Q2 24
$525.9M
Q1 24
$483.6M
Total Assets
ARWR
ARWR
FIVN
FIVN
Q4 25
$1.6B
$1.8B
Q3 25
$1.8B
Q2 25
$1.7B
Q1 25
$2.1B
Q4 24
$2.1B
Q3 24
$2.0B
Q2 24
$1.9B
Q1 24
$1.9B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ARWR
ARWR
FIVN
FIVN
Operating Cash FlowLast quarter
$13.5M
$83.6M
Free Cash FlowOCF − Capex
$11.3M
$77.3M
FCF MarginFCF / Revenue
4.3%
25.8%
Capex IntensityCapex / Revenue
0.8%
2.1%
Cash ConversionOCF / Net Profit
0.44×
TTM Free Cash FlowTrailing 4 quarters
$201.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ARWR
ARWR
FIVN
FIVN
Q4 25
$13.5M
$83.6M
Q3 25
$59.2M
Q2 25
$35.1M
Q1 25
$48.4M
Q4 24
$49.8M
Q3 24
$41.1M
Q2 24
$19.9M
Q1 24
$32.4M
Free Cash Flow
ARWR
ARWR
FIVN
FIVN
Q4 25
$11.3M
$77.3M
Q3 25
$48.7M
Q2 25
$31.6M
Q1 25
$43.7M
Q4 24
$40.5M
Q3 24
$26.7M
Q2 24
$13.1M
Q1 24
$20.4M
FCF Margin
ARWR
ARWR
FIVN
FIVN
Q4 25
4.3%
25.8%
Q3 25
17.0%
Q2 25
11.1%
Q1 25
15.6%
Q4 24
14.5%
Q3 24
10.1%
Q2 24
5.2%
Q1 24
8.3%
Capex Intensity
ARWR
ARWR
FIVN
FIVN
Q4 25
0.8%
2.1%
Q3 25
3.7%
Q2 25
1.2%
Q1 25
1.7%
Q4 24
3.3%
Q3 24
5.4%
Q2 24
2.7%
Q1 24
4.8%
Cash Conversion
ARWR
ARWR
FIVN
FIVN
Q4 25
0.44×
Q3 25
3.29×
Q2 25
30.38×
Q1 25
84.00×
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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