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Side-by-side financial comparison of ASSEMBLY BIOSCIENCES, INC. (ASMB) and American Express (AXP). Click either name above to swap in a different company.

American Express is the larger business by last-quarter revenue ($18.9M vs $10.8M, roughly 1.8× ASSEMBLY BIOSCIENCES, INC.). American Express runs the higher net margin — 15.7% vs -85.2%, a 100.9% gap on every dollar of revenue. On growth, ASSEMBLY BIOSCIENCES, INC. posted the faster year-over-year revenue change (57.6% vs 11.4%).

Pacific Biosciences of California, Inc. is an American biotechnology company founded in 2004 that develops and manufactures systems for gene sequencing and some novel real time biological observation. PacBio has two principal sequencing platforms: single-molecule real-time sequencing (SMRT), based on the properties of zero-mode waveguides and sequencing by binding (SBB) chemistry, which uses native nucleotides and scarless incorporation for DNA binding and extension.

American Express Company, together with its subsidiaries, provides charge and credit payment card products, and travel-related services worldwide. The company operates through three segments: Global Consumer Services Group, Global Commercial Services, and Global Merchant and Network Services. Its products and services include payment and financing products; network services; accounts payable expense management products and services; and travel and lifestyle services. The company's products an...

ASMB vs AXP — Head-to-Head

Bigger by revenue
AXP
AXP
1.8× larger
AXP
$18.9M
$10.8M
ASMB
Growing faster (revenue YoY)
ASMB
ASMB
+46.2% gap
ASMB
57.6%
11.4%
AXP
Higher net margin
AXP
AXP
100.9% more per $
AXP
15.7%
-85.2%
ASMB

Income Statement — Q3 FY2025 vs Q1 FY2026

Metric
ASMB
ASMB
AXP
AXP
Revenue
$10.8M
$18.9M
Net Profit
$-9.2M
$3.0M
Gross Margin
Operating Margin
-100.9%
Net Margin
-85.2%
15.7%
Revenue YoY
57.6%
11.4%
Net Profit YoY
4.3%
15.0%
EPS (diluted)
$-0.72

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ASMB
ASMB
AXP
AXP
Q1 26
$18.9M
Q4 25
$10.9B
Q3 25
$10.8M
$10.4B
Q2 25
$9.6M
$10.3B
Q1 25
$9.4M
$9.6B
Q4 24
$7.4M
$10.0B
Q3 24
$6.8M
$9.7B
Q2 24
$8.5M
$9.8B
Net Profit
ASMB
ASMB
AXP
AXP
Q1 26
$3.0M
Q4 25
$2.5B
Q3 25
$-9.2M
$2.9B
Q2 25
$-10.2M
$2.9B
Q1 25
$-8.8M
$2.6B
Q4 24
$2.2B
Q3 24
$-9.6M
$2.5B
Q2 24
$-11.2M
$3.0B
Operating Margin
ASMB
ASMB
AXP
AXP
Q1 26
Q4 25
28.2%
Q3 25
-100.9%
36.7%
Q2 25
-115.2%
34.4%
Q1 25
-105.5%
34.6%
Q4 24
27.7%
Q3 24
-160.1%
33.0%
Q2 24
-143.0%
38.6%
Net Margin
ASMB
ASMB
AXP
AXP
Q1 26
15.7%
Q4 25
22.5%
Q3 25
-85.2%
27.9%
Q2 25
-105.9%
28.0%
Q1 25
-93.6%
26.8%
Q4 24
21.8%
Q3 24
-140.4%
25.8%
Q2 24
-130.7%
30.7%
EPS (diluted)
ASMB
ASMB
AXP
AXP
Q1 26
Q4 25
$3.52
Q3 25
$-0.72
$4.14
Q2 25
$-1.33
$4.08
Q1 25
$-1.17
$3.64
Q4 24
$3.04
Q3 24
$-1.51
$3.49
Q2 24
$-1.98
$4.15

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ASMB
ASMB
AXP
AXP
Cash + ST InvestmentsLiquidity on hand
$22.5M
Total DebtLower is stronger
$60.4M
Stockholders' EquityBook value
$182.7M
$34.0M
Total Assets
$240.0M
$308.9M
Debt / EquityLower = less leverage
1.78×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ASMB
ASMB
AXP
AXP
Q1 26
Q4 25
$742.0M
Q3 25
$22.5M
$1.3B
Q2 25
$24.0M
$197.0M
Q1 25
$23.4M
$261.0M
Q4 24
$38.3M
$221.0M
Q3 24
$28.5M
$120.0M
Q2 24
$19.2M
$188.0M
Total Debt
ASMB
ASMB
AXP
AXP
Q1 26
$60.4M
Q4 25
$56.4B
Q3 25
$57.8B
Q2 25
$58.2B
Q1 25
$51.2B
Q4 24
$49.7B
Q3 24
$53.5B
Q2 24
$51.5B
Stockholders' Equity
ASMB
ASMB
AXP
AXP
Q1 26
$34.0M
Q4 25
$33.5B
Q3 25
$182.7M
$32.4B
Q2 25
$18.1M
$32.3B
Q1 25
$27.1M
$31.2B
Q4 24
$33.4M
$30.3B
Q3 24
$26.0M
$29.7B
Q2 24
$34.7M
$29.5B
Total Assets
ASMB
ASMB
AXP
AXP
Q1 26
$308.9M
Q4 25
$300.1B
Q3 25
$240.0M
$297.6B
Q2 25
$80.8M
$295.6B
Q1 25
$99.0M
$282.2B
Q4 24
$119.2M
$271.5B
Q3 24
$100.3M
$271.0B
Q2 24
$115.3M
$272.2B
Debt / Equity
ASMB
ASMB
AXP
AXP
Q1 26
1.78×
Q4 25
1.68×
Q3 25
1.78×
Q2 25
1.80×
Q1 25
1.64×
Q4 24
1.64×
Q3 24
1.80×
Q2 24
1.74×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ASMB
ASMB
AXP
AXP
Operating Cash FlowLast quarter
$-15.1M
Free Cash FlowOCF − Capex
$-15.2M
FCF MarginFCF / Revenue
-140.7%
Capex IntensityCapex / Revenue
0.4%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ASMB
ASMB
AXP
AXP
Q1 26
Q4 25
$3.1B
Q3 25
$-15.1M
$6.2B
Q2 25
$-16.8M
$4.4B
Q1 25
$-23.4M
$4.8B
Q4 24
$-51.1M
$5.8B
Q3 24
$-15.2M
$-1.8B
Q2 24
$-17.1M
$4.5B
Free Cash Flow
ASMB
ASMB
AXP
AXP
Q1 26
Q4 25
$2.3B
Q3 25
$-15.2M
$5.6B
Q2 25
$3.7B
Q1 25
$4.3B
Q4 24
$-51.1M
$5.3B
Q3 24
$-2.3B
Q2 24
$-17.1M
$4.0B
FCF Margin
ASMB
ASMB
AXP
AXP
Q1 26
Q4 25
21.4%
Q3 25
-140.7%
53.6%
Q2 25
36.3%
Q1 25
45.0%
Q4 24
-695.2%
53.1%
Q3 24
-23.3%
Q2 24
-200.6%
40.4%
Capex Intensity
ASMB
ASMB
AXP
AXP
Q1 26
Q4 25
6.6%
Q3 25
0.4%
6.3%
Q2 25
0.0%
6.0%
Q1 25
0.0%
4.5%
Q4 24
0.4%
5.0%
Q3 24
0.0%
4.7%
Q2 24
0.2%
5.8%
Cash Conversion
ASMB
ASMB
AXP
AXP
Q1 26
Q4 25
1.25×
Q3 25
2.15×
Q2 25
1.51×
Q1 25
1.84×
Q4 24
2.66×
Q3 24
-0.72×
Q2 24
1.50×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ASMB
ASMB

Segment breakdown not available.

AXP
AXP

Discount revenue$9.5M50%
Other$8.9M47%
Deposits with banks and other$512.0K3%

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