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Side-by-side financial comparison of American Express (AXP) and Cue Biopharma, Inc. (CUE). Click either name above to swap in a different company.
Cue Biopharma, Inc. is the larger business by last-quarter revenue ($21.9M vs $18.9M, roughly 1.2× American Express). American Express runs the higher net margin — 15.7% vs 7.2%, a 8.5% gap on every dollar of revenue. On growth, Cue Biopharma, Inc. posted the faster year-over-year revenue change (1292.3% vs 11.4%). Over the past eight quarters, Cue Biopharma, Inc.'s revenue compounded faster (257.5% CAGR vs -95.6%).
American Express Company, together with its subsidiaries, provides charge and credit payment card products, and travel-related services worldwide. The company operates through three segments: Global Consumer Services Group, Global Commercial Services, and Global Merchant and Network Services. Its products and services include payment and financing products; network services; accounts payable expense management products and services; and travel and lifestyle services. The company's products an...
Cue Biopharma is a clinical-stage biotechnology company focused on developing novel targeted immunotherapies for cancer, autoimmune disorders, and inflammatory diseases. Its proprietary platform enables precise T-cell activity modulation, with core operations in North America and global pharma partnerships to advance lead product candidates through clinical trials.
AXP vs CUE — Head-to-Head
Income Statement — Q1 FY2026 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $18.9M | $21.9M |
| Net Profit | $3.0M | $1.6M |
| Gross Margin | — | — |
| Operating Margin | — | 9.0% |
| Net Margin | 15.7% | 7.2% |
| Revenue YoY | 11.4% | 1292.3% |
| Net Profit YoY | 15.0% | 116.7% |
| EPS (diluted) | — | $0.05 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | $18.9M | — | ||
| Q4 25 | $10.9B | $21.9M | ||
| Q3 25 | $10.4B | $2.1M | ||
| Q2 25 | $10.3B | $3.0M | ||
| Q1 25 | $9.6B | $421.0K | ||
| Q4 24 | $10.0B | $1.6M | ||
| Q3 24 | $9.7B | $3.3M | ||
| Q2 24 | $9.8B | $2.7M |
| Q1 26 | $3.0M | — | ||
| Q4 25 | $2.5B | $1.6M | ||
| Q3 25 | $2.9B | $-7.4M | ||
| Q2 25 | $2.9B | $-8.5M | ||
| Q1 25 | $2.6B | $-12.3M | ||
| Q4 24 | $2.2B | — | ||
| Q3 24 | $2.5B | $-8.7M | ||
| Q2 24 | $3.0B | $-10.2M |
| Q1 26 | — | — | ||
| Q4 25 | 28.2% | 9.0% | ||
| Q3 25 | 36.7% | -353.4% | ||
| Q2 25 | 34.4% | -292.3% | ||
| Q1 25 | 34.6% | -2921.4% | ||
| Q4 24 | 27.7% | — | ||
| Q3 24 | 33.0% | -264.2% | ||
| Q2 24 | 38.6% | -390.6% |
| Q1 26 | 15.7% | — | ||
| Q4 25 | 22.5% | 7.2% | ||
| Q3 25 | 27.9% | -346.6% | ||
| Q2 25 | 28.0% | -287.1% | ||
| Q1 25 | 26.8% | -2911.4% | ||
| Q4 24 | 21.8% | — | ||
| Q3 24 | 25.8% | -259.6% | ||
| Q2 24 | 30.7% | -382.7% |
| Q1 26 | — | — | ||
| Q4 25 | $3.52 | $0.05 | ||
| Q3 25 | $4.14 | $-0.07 | ||
| Q2 25 | $4.08 | $-0.09 | ||
| Q1 25 | $3.64 | $-0.17 | ||
| Q4 24 | $3.04 | — | ||
| Q3 24 | $3.49 | $-0.17 | ||
| Q2 24 | $4.15 | $-0.20 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | — | $27.1M |
| Total DebtLower is stronger | $60.4M | — |
| Stockholders' EquityBook value | $34.0M | $26.4M |
| Total Assets | $308.9M | $42.2M |
| Debt / EquityLower = less leverage | 1.78× | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $742.0M | $27.1M | ||
| Q3 25 | $1.3B | $11.7M | ||
| Q2 25 | $197.0M | $27.5M | ||
| Q1 25 | $261.0M | $13.1M | ||
| Q4 24 | $221.0M | $22.5M | ||
| Q3 24 | $120.0M | $32.4M | ||
| Q2 24 | $188.0M | $30.0M |
| Q1 26 | $60.4M | — | ||
| Q4 25 | $56.4B | — | ||
| Q3 25 | $57.8B | — | ||
| Q2 25 | $58.2B | — | ||
| Q1 25 | $51.2B | — | ||
| Q4 24 | $49.7B | — | ||
| Q3 24 | $53.5B | $1.0M | ||
| Q2 24 | $51.5B | $2.0M |
| Q1 26 | $34.0M | — | ||
| Q4 25 | $33.5B | $26.4M | ||
| Q3 25 | $32.4B | $13.2M | ||
| Q2 25 | $32.3B | $18.2M | ||
| Q1 25 | $31.2B | $6.6M | ||
| Q4 24 | $30.3B | $17.5M | ||
| Q3 24 | $29.7B | $25.4M | ||
| Q2 24 | $29.5B | $21.6M |
| Q1 26 | $308.9M | — | ||
| Q4 25 | $300.1B | $42.2M | ||
| Q3 25 | $297.6B | $31.6M | ||
| Q2 25 | $295.6B | $40.7M | ||
| Q1 25 | $282.2B | $22.3M | ||
| Q4 24 | $271.5B | $32.2M | ||
| Q3 24 | $271.0B | $44.8M | ||
| Q2 24 | $272.2B | $42.3M |
| Q1 26 | 1.78× | — | ||
| Q4 25 | 1.68× | — | ||
| Q3 25 | 1.78× | — | ||
| Q2 25 | 1.80× | — | ||
| Q1 25 | 1.64× | — | ||
| Q4 24 | 1.64× | — | ||
| Q3 24 | 1.80× | 0.04× | ||
| Q2 24 | 1.74× | 0.09× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | — | $-1.1M |
| Free Cash FlowOCF − Capex | — | — |
| FCF MarginFCF / Revenue | — | — |
| Capex IntensityCapex / Revenue | — | 0.0% |
| Cash ConversionOCF / Net Profit | — | -0.68× |
| TTM Free Cash FlowTrailing 4 quarters | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $3.1B | $-1.1M | ||
| Q3 25 | $6.2B | $-9.0M | ||
| Q2 25 | $4.4B | $-3.4M | ||
| Q1 25 | $4.8B | $-8.2M | ||
| Q4 24 | $5.8B | $-36.3M | ||
| Q3 24 | $-1.8B | $-7.5M | ||
| Q2 24 | $4.5B | $-10.0M |
| Q1 26 | — | — | ||
| Q4 25 | $2.3B | — | ||
| Q3 25 | $5.6B | — | ||
| Q2 25 | $3.7B | $-3.4M | ||
| Q1 25 | $4.3B | $-8.3M | ||
| Q4 24 | $5.3B | $-36.4M | ||
| Q3 24 | $-2.3B | $-7.5M | ||
| Q2 24 | $4.0B | $-10.0M |
| Q1 26 | — | — | ||
| Q4 25 | 21.4% | — | ||
| Q3 25 | 53.6% | — | ||
| Q2 25 | 36.3% | -116.5% | ||
| Q1 25 | 45.0% | -1976.7% | ||
| Q4 24 | 53.1% | -2309.3% | ||
| Q3 24 | -23.3% | -225.7% | ||
| Q2 24 | 40.4% | -376.2% |
| Q1 26 | — | — | ||
| Q4 25 | 6.6% | 0.0% | ||
| Q3 25 | 6.3% | 0.0% | ||
| Q2 25 | 6.0% | 0.9% | ||
| Q1 25 | 4.5% | 35.6% | ||
| Q4 24 | 5.0% | 4.2% | ||
| Q3 24 | 4.7% | 0.0% | ||
| Q2 24 | 5.8% | 0.4% |
| Q1 26 | — | — | ||
| Q4 25 | 1.25× | -0.68× | ||
| Q3 25 | 2.15× | — | ||
| Q2 25 | 1.51× | — | ||
| Q1 25 | 1.84× | — | ||
| Q4 24 | 2.66× | — | ||
| Q3 24 | -0.72× | — | ||
| Q2 24 | 1.50× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AXP
| Discount revenue | $9.5M | 50% |
| Other | $8.9M | 47% |
| Deposits with banks and other | $512.0K | 3% |
CUE
| Immuno Scape Collaboration And License Agreement | $9.5M | 43% |
| BI Collaboration And License Agreement | $8.1M | 37% |
| Other | $4.3M | 20% |
