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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and Five9, Inc. (FIVN). Click either name above to swap in a different company.

Five9, Inc. is the larger business by last-quarter revenue ($300.3M vs $196.0M, roughly 1.5× Axsome Therapeutics, Inc.). On growth, Axsome Therapeutics, Inc. posted the faster year-over-year revenue change (65.0% vs 7.8%). Five9, Inc. produced more free cash flow last quarter ($77.3M vs $-18.7M). Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (61.7% CAGR vs 10.3%).

Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.

Five9, Inc. is a leading global provider of cloud-native contact center software and solutions. It serves enterprises of all sizes across retail, healthcare, financial services, and technology sectors, offering omnichannel customer engagement tools, AI-powered automation, workforce management, and analytics to boost customer experience and operational efficiency.

AXSM vs FIVN — Head-to-Head

Bigger by revenue
FIVN
FIVN
1.5× larger
FIVN
$300.3M
$196.0M
AXSM
Growing faster (revenue YoY)
AXSM
AXSM
+57.3% gap
AXSM
65.0%
7.8%
FIVN
More free cash flow
FIVN
FIVN
$96.0M more FCF
FIVN
$77.3M
$-18.7M
AXSM
Faster 2-yr revenue CAGR
AXSM
AXSM
Annualised
AXSM
61.7%
10.3%
FIVN

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AXSM
AXSM
FIVN
FIVN
Revenue
$196.0M
$300.3M
Net Profit
$-28.6M
Gross Margin
55.4%
Operating Margin
-13.8%
6.6%
Net Margin
-14.6%
Revenue YoY
65.0%
7.8%
Net Profit YoY
61.9%
EPS (diluted)
$-0.55
$0.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXSM
AXSM
FIVN
FIVN
Q4 25
$196.0M
$300.3M
Q3 25
$171.0M
$285.8M
Q2 25
$150.0M
$283.3M
Q1 25
$121.5M
$279.7M
Q4 24
$118.8M
$278.7M
Q3 24
$104.8M
$264.2M
Q2 24
$87.2M
$252.1M
Q1 24
$75.0M
$247.0M
Net Profit
AXSM
AXSM
FIVN
FIVN
Q4 25
$-28.6M
Q3 25
$-47.2M
$18.0M
Q2 25
$-48.0M
$1.2M
Q1 25
$-59.4M
$576.0K
Q4 24
$-74.9M
Q3 24
$-64.6M
$-4.5M
Q2 24
$-79.3M
$-12.8M
Q1 24
$-68.4M
$-7.1M
Gross Margin
AXSM
AXSM
FIVN
FIVN
Q4 25
55.4%
Q3 25
55.0%
Q2 25
54.9%
Q1 25
55.0%
Q4 24
56.0%
Q3 24
53.8%
Q2 24
53.0%
Q1 24
53.6%
Operating Margin
AXSM
AXSM
FIVN
FIVN
Q4 25
-13.8%
6.6%
Q3 25
-27.0%
5.6%
Q2 25
-24.5%
-0.6%
Q1 25
-46.9%
-1.9%
Q4 24
-61.1%
1.5%
Q3 24
-59.8%
-5.8%
Q2 24
-89.5%
-7.7%
Q1 24
-89.7%
-8.4%
Net Margin
AXSM
AXSM
FIVN
FIVN
Q4 25
-14.6%
Q3 25
-27.6%
6.3%
Q2 25
-32.0%
0.4%
Q1 25
-48.9%
0.2%
Q4 24
-63.1%
Q3 24
-61.7%
-1.7%
Q2 24
-91.0%
-5.1%
Q1 24
-91.1%
-2.9%
EPS (diluted)
AXSM
AXSM
FIVN
FIVN
Q4 25
$-0.55
$0.22
Q3 25
$-0.94
$0.21
Q2 25
$-0.97
$0.01
Q1 25
$-1.22
$0.01
Q4 24
$-1.54
$0.16
Q3 24
$-1.34
$-0.06
Q2 24
$-1.67
$-0.17
Q1 24
$-1.44
$-0.10

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXSM
AXSM
FIVN
FIVN
Cash + ST InvestmentsLiquidity on hand
$322.9M
$232.1M
Total DebtLower is stronger
Stockholders' EquityBook value
$88.3M
$785.8M
Total Assets
$689.8M
$1.8B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXSM
AXSM
FIVN
FIVN
Q4 25
$322.9M
$232.1M
Q3 25
$325.3M
$193.4M
Q2 25
$303.0M
$205.5M
Q1 25
$300.9M
$370.3M
Q4 24
$315.4M
$362.5M
Q3 24
$327.3M
$291.0M
Q2 24
$315.7M
$175.7M
Q1 24
$331.4M
$240.2M
Stockholders' Equity
AXSM
AXSM
FIVN
FIVN
Q4 25
$88.3M
$785.8M
Q3 25
$73.7M
$775.3M
Q2 25
$73.1M
$717.4M
Q1 25
$53.2M
$664.3M
Q4 24
$57.0M
$622.2M
Q3 24
$92.9M
$565.6M
Q2 24
$102.9M
$525.9M
Q1 24
$144.0M
$483.6M
Total Assets
AXSM
AXSM
FIVN
FIVN
Q4 25
$689.8M
$1.8B
Q3 25
$669.3M
$1.8B
Q2 25
$639.8M
$1.7B
Q1 25
$596.7M
$2.1B
Q4 24
$568.5M
$2.1B
Q3 24
$561.5M
$2.0B
Q2 24
$548.2M
$1.9B
Q1 24
$545.7M
$1.9B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AXSM
AXSM
FIVN
FIVN
Operating Cash FlowLast quarter
$-18.7M
$83.6M
Free Cash FlowOCF − Capex
$-18.7M
$77.3M
FCF MarginFCF / Revenue
-9.6%
25.8%
Capex IntensityCapex / Revenue
0.0%
2.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-93.9M
$201.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AXSM
AXSM
FIVN
FIVN
Q4 25
$-18.7M
$83.6M
Q3 25
$1.0M
$59.2M
Q2 25
$-32.4M
$35.1M
Q1 25
$-43.4M
$48.4M
Q4 24
$-26.2M
$49.8M
Q3 24
$-18.6M
$41.1M
Q2 24
$-30.1M
$19.9M
Q1 24
$-53.5M
$32.4M
Free Cash Flow
AXSM
AXSM
FIVN
FIVN
Q4 25
$-18.7M
$77.3M
Q3 25
$988.0K
$48.7M
Q2 25
$-32.4M
$31.6M
Q1 25
$-43.7M
$43.7M
Q4 24
$-26.2M
$40.5M
Q3 24
$-18.7M
$26.7M
Q2 24
$-30.2M
$13.1M
Q1 24
$-53.6M
$20.4M
FCF Margin
AXSM
AXSM
FIVN
FIVN
Q4 25
-9.6%
25.8%
Q3 25
0.6%
17.0%
Q2 25
-21.6%
11.1%
Q1 25
-36.0%
15.6%
Q4 24
-22.1%
14.5%
Q3 24
-17.9%
10.1%
Q2 24
-34.6%
5.2%
Q1 24
-71.4%
8.3%
Capex Intensity
AXSM
AXSM
FIVN
FIVN
Q4 25
0.0%
2.1%
Q3 25
0.0%
3.7%
Q2 25
0.0%
1.2%
Q1 25
0.3%
1.7%
Q4 24
0.0%
3.3%
Q3 24
0.1%
5.4%
Q2 24
0.1%
2.7%
Q1 24
0.1%
4.8%
Cash Conversion
AXSM
AXSM
FIVN
FIVN
Q4 25
Q3 25
3.29×
Q2 25
30.38×
Q1 25
84.00×
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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