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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and Enpro Inc. (NPO). Click either name above to swap in a different company.

Enpro Inc. is the larger business by last-quarter revenue ($295.4M vs $196.0M, roughly 1.5× Axsome Therapeutics, Inc.). Enpro Inc. runs the higher net margin — -10.8% vs -14.6%, a 3.7% gap on every dollar of revenue. On growth, Axsome Therapeutics, Inc. posted the faster year-over-year revenue change (65.0% vs 14.3%). Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (61.7% CAGR vs 7.1%).

Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.

Enpro is a US-based industrial technology company that designs and manufactures products and materials for technology-intensive sectors. The company serves industries such as semiconductors, aerospace, power generation, heavy-duty trucking, agricultural machinery, chemical processing, pulp and paper, and life sciences from 61 primary manufacturing facilities located in 12 countries, worldwide. It is organized under three segments: Sealing Technologies, Advanced Surface Technologies, and Engin...

AXSM vs NPO — Head-to-Head

Bigger by revenue
NPO
NPO
1.5× larger
NPO
$295.4M
$196.0M
AXSM
Growing faster (revenue YoY)
AXSM
AXSM
+50.7% gap
AXSM
65.0%
14.3%
NPO
Higher net margin
NPO
NPO
3.7% more per $
NPO
-10.8%
-14.6%
AXSM
Faster 2-yr revenue CAGR
AXSM
AXSM
Annualised
AXSM
61.7%
7.1%
NPO

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
AXSM
AXSM
NPO
NPO
Revenue
$196.0M
$295.4M
Net Profit
$-28.6M
$-32.0M
Gross Margin
42.1%
Operating Margin
-13.8%
11.2%
Net Margin
-14.6%
-10.8%
Revenue YoY
65.0%
14.3%
Net Profit YoY
61.9%
-330.2%
EPS (diluted)
$-0.55
$-1.50

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXSM
AXSM
NPO
NPO
Q4 25
$196.0M
$295.4M
Q3 25
$171.0M
$286.6M
Q2 25
$150.0M
$288.1M
Q1 25
$121.5M
$273.2M
Q4 24
$118.8M
$258.4M
Q3 24
$104.8M
$260.9M
Q2 24
$87.2M
$271.9M
Q1 24
$75.0M
$257.5M
Net Profit
AXSM
AXSM
NPO
NPO
Q4 25
$-28.6M
$-32.0M
Q3 25
$-47.2M
$21.6M
Q2 25
$-48.0M
$26.4M
Q1 25
$-59.4M
$24.5M
Q4 24
$-74.9M
$13.9M
Q3 24
$-64.6M
$19.8M
Q2 24
$-79.3M
$26.7M
Q1 24
$-68.4M
$12.5M
Gross Margin
AXSM
AXSM
NPO
NPO
Q4 25
42.1%
Q3 25
41.9%
Q2 25
43.3%
Q1 25
43.3%
Q4 24
42.3%
Q3 24
42.3%
Q2 24
43.8%
Q1 24
41.2%
Operating Margin
AXSM
AXSM
NPO
NPO
Q4 25
-13.8%
11.2%
Q3 25
-27.0%
14.3%
Q2 25
-24.5%
15.9%
Q1 25
-46.9%
15.3%
Q4 24
-61.1%
12.5%
Q3 24
-59.8%
13.1%
Q2 24
-89.5%
17.7%
Q1 24
-89.7%
10.9%
Net Margin
AXSM
AXSM
NPO
NPO
Q4 25
-14.6%
-10.8%
Q3 25
-27.6%
7.5%
Q2 25
-32.0%
9.2%
Q1 25
-48.9%
9.0%
Q4 24
-63.1%
5.4%
Q3 24
-61.7%
7.6%
Q2 24
-91.0%
9.8%
Q1 24
-91.1%
4.9%
EPS (diluted)
AXSM
AXSM
NPO
NPO
Q4 25
$-0.55
$-1.50
Q3 25
$-0.94
$1.01
Q2 25
$-0.97
$1.25
Q1 25
$-1.22
$1.15
Q4 24
$-1.54
$0.65
Q3 24
$-1.34
$0.94
Q2 24
$-1.67
$1.27
Q1 24
$-1.44
$0.59

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXSM
AXSM
NPO
NPO
Cash + ST InvestmentsLiquidity on hand
$322.9M
$114.7M
Total DebtLower is stronger
$655.3M
Stockholders' EquityBook value
$88.3M
$1.5B
Total Assets
$689.8M
$2.7B
Debt / EquityLower = less leverage
0.42×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXSM
AXSM
NPO
NPO
Q4 25
$322.9M
$114.7M
Q3 25
$325.3M
$132.9M
Q2 25
$303.0M
$107.1M
Q1 25
$300.9M
$240.3M
Q4 24
$315.4M
$236.3M
Q3 24
$327.3M
$206.9M
Q2 24
$315.7M
$175.9M
Q1 24
$331.4M
$163.9M
Total Debt
AXSM
AXSM
NPO
NPO
Q4 25
$655.3M
Q3 25
Q2 25
Q1 25
Q4 24
$640.1M
Q3 24
Q2 24
Q1 24
$644.9M
Stockholders' Equity
AXSM
AXSM
NPO
NPO
Q4 25
$88.3M
$1.5B
Q3 25
$73.7M
$1.5B
Q2 25
$73.1M
$1.5B
Q1 25
$53.2M
$1.5B
Q4 24
$57.0M
$1.4B
Q3 24
$92.9M
$1.5B
Q2 24
$102.9M
$1.4B
Q1 24
$144.0M
$1.4B
Total Assets
AXSM
AXSM
NPO
NPO
Q4 25
$689.8M
$2.7B
Q3 25
$669.3M
$2.4B
Q2 25
$639.8M
$2.4B
Q1 25
$596.7M
$2.5B
Q4 24
$568.5M
$2.5B
Q3 24
$561.5M
$2.5B
Q2 24
$548.2M
$2.5B
Q1 24
$545.7M
$2.5B
Debt / Equity
AXSM
AXSM
NPO
NPO
Q4 25
0.42×
Q3 25
Q2 25
Q1 25
Q4 24
0.45×
Q3 24
Q2 24
Q1 24
0.46×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AXSM
AXSM
NPO
NPO
Operating Cash FlowLast quarter
$-18.7M
Free Cash FlowOCF − Capex
$-18.7M
FCF MarginFCF / Revenue
-9.6%
Capex IntensityCapex / Revenue
0.0%
4.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-93.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AXSM
AXSM
NPO
NPO
Q4 25
$-18.7M
Q3 25
$1.0M
$65.3M
Q2 25
$-32.4M
$52.2M
Q1 25
$-43.4M
$21.0M
Q4 24
$-26.2M
$59.4M
Q3 24
$-18.6M
$54.0M
Q2 24
$-30.1M
$43.2M
Q1 24
$-53.5M
$6.3M
Free Cash Flow
AXSM
AXSM
NPO
NPO
Q4 25
$-18.7M
Q3 25
$988.0K
$53.4M
Q2 25
$-32.4M
$42.3M
Q1 25
$-43.7M
$13.0M
Q4 24
$-26.2M
$49.1M
Q3 24
$-18.7M
$48.3M
Q2 24
$-30.2M
$38.3M
Q1 24
$-53.6M
$-1.9M
FCF Margin
AXSM
AXSM
NPO
NPO
Q4 25
-9.6%
Q3 25
0.6%
18.6%
Q2 25
-21.6%
14.7%
Q1 25
-36.0%
4.8%
Q4 24
-22.1%
19.0%
Q3 24
-17.9%
18.5%
Q2 24
-34.6%
14.1%
Q1 24
-71.4%
-0.7%
Capex Intensity
AXSM
AXSM
NPO
NPO
Q4 25
0.0%
4.1%
Q3 25
0.0%
4.2%
Q2 25
0.0%
3.4%
Q1 25
0.3%
2.9%
Q4 24
0.0%
4.0%
Q3 24
0.1%
2.2%
Q2 24
0.1%
1.8%
Q1 24
0.1%
3.2%
Cash Conversion
AXSM
AXSM
NPO
NPO
Q4 25
Q3 25
3.02×
Q2 25
1.98×
Q1 25
0.86×
Q4 24
4.27×
Q3 24
2.73×
Q2 24
1.62×
Q1 24
0.50×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AXSM
AXSM

Segment breakdown not available.

NPO
NPO

Sealing Technologies Segment$187.0M63%
General Industrial$71.3M24%
Power Generation$19.9M7%
Oiland Gas Market$15.0M5%
Semiconductors$2.2M1%

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