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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and OCTAVE SPECIALTY GROUP INC (OSG). Click either name above to swap in a different company.

Axsome Therapeutics, Inc. is the larger business by last-quarter revenue ($191.2M vs $104.2M, roughly 1.8× OCTAVE SPECIALTY GROUP INC). On growth, OCTAVE SPECIALTY GROUP INC posted the faster year-over-year revenue change (66.0% vs 57.4%). Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (48.1% CAGR vs 42.9%).

Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.

Octave Specialty Group Inc. is a specialty insurance holding company that provides tailored property and casualty insurance products. Its core business focuses on excess and surplus lines, catering to commercial and individual clients across primary North American markets with customized risk coverage solutions.

AXSM vs OSG — Head-to-Head

Bigger by revenue
AXSM
AXSM
1.8× larger
AXSM
$191.2M
$104.2M
OSG
Growing faster (revenue YoY)
OSG
OSG
+8.6% gap
OSG
66.0%
57.4%
AXSM
Faster 2-yr revenue CAGR
AXSM
AXSM
Annualised
AXSM
48.1%
42.9%
OSG

Income Statement — Q1 FY2026 vs Q1 FY2026

Metric
AXSM
AXSM
OSG
OSG
Revenue
$191.2M
$104.2M
Net Profit
$-6.9M
Gross Margin
Operating Margin
-33.1%
Net Margin
-6.6%
Revenue YoY
57.4%
66.0%
Net Profit YoY
EPS (diluted)
$-0.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AXSM
AXSM
OSG
OSG
Q1 26
$191.2M
$104.2M
Q4 25
$196.0M
$66.9M
Q3 25
$171.0M
$66.6M
Q2 25
$150.0M
$55.0M
Q1 25
$121.5M
$62.8M
Q4 24
$118.8M
$65.2M
Q3 24
$104.8M
$70.0M
Q2 24
$87.2M
$51.0M
Net Profit
AXSM
AXSM
OSG
OSG
Q1 26
$-6.9M
Q4 25
$-28.6M
$-29.7M
Q3 25
$-47.2M
$-112.6M
Q2 25
$-48.0M
$-72.7M
Q1 25
$-59.4M
$-44.7M
Q4 24
$-74.9M
$-20.9M
Q3 24
$-64.6M
$-27.5M
Q2 24
$-79.3M
$-750.0K
Operating Margin
AXSM
AXSM
OSG
OSG
Q1 26
-33.1%
Q4 25
-13.8%
-76.7%
Q3 25
-27.0%
-48.2%
Q2 25
-24.5%
-41.8%
Q1 25
-46.9%
-24.1%
Q4 24
-61.1%
-55.5%
Q3 24
-59.8%
-29.7%
Q2 24
-89.5%
-28.9%
Net Margin
AXSM
AXSM
OSG
OSG
Q1 26
-6.6%
Q4 25
-14.6%
-73.8%
Q3 25
-27.6%
-169.1%
Q2 25
-32.0%
-132.3%
Q1 25
-48.9%
-71.3%
Q4 24
-63.1%
-55.1%
Q3 24
-61.7%
-39.3%
Q2 24
-91.0%
-1.5%
EPS (diluted)
AXSM
AXSM
OSG
OSG
Q1 26
$-0.13
Q4 25
$-0.55
$-0.82
Q3 25
$-0.94
$-2.35
Q2 25
$-0.97
$-1.54
Q1 25
$-1.22
$-1.22
Q4 24
$-1.54
$-11.75
Q3 24
$-1.34
$-0.63
Q2 24
$-1.67
$-0.02

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AXSM
AXSM
OSG
OSG
Cash + ST InvestmentsLiquidity on hand
$305.1M
Total DebtLower is stronger
$70.0M
$117.1M
Stockholders' EquityBook value
$833.6M
Total Assets
$713.6M
$2.3B
Debt / EquityLower = less leverage
0.14×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AXSM
AXSM
OSG
OSG
Q1 26
$305.1M
Q4 25
$322.9M
$146.4M
Q3 25
$325.3M
$27.5M
Q2 25
$303.0M
$22.5M
Q1 25
$300.9M
$34.1M
Q4 24
$315.4M
$157.2M
Q3 24
$327.3M
$40.8M
Q2 24
$315.7M
$14.6M
Total Debt
AXSM
AXSM
OSG
OSG
Q1 26
$70.0M
$117.1M
Q4 25
$117.6M
Q3 25
Q2 25
Q1 25
Q4 24
$0
Q3 24
$518.0M
Q2 24
$515.0M
Stockholders' Equity
AXSM
AXSM
OSG
OSG
Q1 26
$833.6M
Q4 25
$88.3M
$715.8M
Q3 25
$73.7M
$843.4M
Q2 25
$73.1M
$859.8M
Q1 25
$53.2M
$852.2M
Q4 24
$57.0M
$798.4M
Q3 24
$92.9M
$1.5B
Q2 24
$102.9M
$1.4B
Total Assets
AXSM
AXSM
OSG
OSG
Q1 26
$713.6M
$2.3B
Q4 25
$689.8M
$2.2B
Q3 25
$669.3M
$2.1B
Q2 25
$639.8M
$8.5B
Q1 25
$596.7M
$8.3B
Q4 24
$568.5M
$8.1B
Q3 24
$561.5M
$9.3B
Q2 24
$548.2M
$8.2B
Debt / Equity
AXSM
AXSM
OSG
OSG
Q1 26
0.14×
Q4 25
0.16×
Q3 25
Q2 25
Q1 25
Q4 24
0.00×
Q3 24
0.35×
Q2 24
0.38×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AXSM
AXSM

Product sales, net$189.4M99%
Royalty revenue and milestone revenue$1.8M1%

OSG
OSG

Commissions$68.2M65%
Other$20.6M20%
Servicing and other fees$9.4M9%
Program fees$3.6M3%
Investment income$2.4M2%

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