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Side-by-side financial comparison of Axsome Therapeutics, Inc. (AXSM) and SPS COMMERCE INC (SPSC). Click either name above to swap in a different company.
Axsome Therapeutics, Inc. is the larger business by last-quarter revenue ($196.0M vs $192.7M, roughly 1.0× SPS COMMERCE INC). SPS COMMERCE INC runs the higher net margin — 13.4% vs -14.6%, a 28.0% gap on every dollar of revenue. On growth, Axsome Therapeutics, Inc. posted the faster year-over-year revenue change (65.0% vs 12.7%). SPS COMMERCE INC produced more free cash flow last quarter ($38.2M vs $-18.7M). Over the past eight quarters, Axsome Therapeutics, Inc.'s revenue compounded faster (61.7% CAGR vs 13.5%).
Jazz Pharmaceuticals plc is a global biopharmaceutical company with a focus on oncology and neuroscience. It was founded in 2003 in California, United States and is now headquartered in Dublin, Ireland.
SPS Commerce, Inc. is a technology and application software company based in the United States that provides cloud-based supply chain management software. The company's headquarters are located in Minneapolis, Minnesota, but it also has a US office in New Jersey, and international locations in Amsterdam, Beijing, Breukelen, Hong Kong, Kyiv, Melbourne, Montpellier, Sydney, and Toronto.
AXSM vs SPSC — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $196.0M | $192.7M |
| Net Profit | $-28.6M | $25.8M |
| Gross Margin | — | 70.4% |
| Operating Margin | -13.8% | 18.0% |
| Net Margin | -14.6% | 13.4% |
| Revenue YoY | 65.0% | 12.7% |
| Net Profit YoY | 61.9% | 47.2% |
| EPS (diluted) | $-0.55 | $0.69 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $196.0M | $192.7M | ||
| Q3 25 | $171.0M | $189.9M | ||
| Q2 25 | $150.0M | $187.4M | ||
| Q1 25 | $121.5M | $181.5M | ||
| Q4 24 | $118.8M | $170.9M | ||
| Q3 24 | $104.8M | $163.7M | ||
| Q2 24 | $87.2M | $153.6M | ||
| Q1 24 | $75.0M | $149.6M |
| Q4 25 | $-28.6M | $25.8M | ||
| Q3 25 | $-47.2M | $25.6M | ||
| Q2 25 | $-48.0M | $19.7M | ||
| Q1 25 | $-59.4M | $22.2M | ||
| Q4 24 | $-74.9M | $17.6M | ||
| Q3 24 | $-64.6M | $23.5M | ||
| Q2 24 | $-79.3M | $18.0M | ||
| Q1 24 | $-68.4M | $18.0M |
| Q4 25 | — | 70.4% | ||
| Q3 25 | — | 69.5% | ||
| Q2 25 | — | 68.1% | ||
| Q1 25 | — | 68.7% | ||
| Q4 24 | — | 67.5% | ||
| Q3 24 | — | 68.5% | ||
| Q2 24 | — | 66.1% | ||
| Q1 24 | — | 65.6% |
| Q4 25 | -13.8% | 18.0% | ||
| Q3 25 | -27.0% | 16.4% | ||
| Q2 25 | -24.5% | 14.1% | ||
| Q1 25 | -46.9% | 14.3% | ||
| Q4 24 | -61.1% | 14.5% | ||
| Q3 24 | -59.8% | 15.6% | ||
| Q2 24 | -89.5% | 15.1% | ||
| Q1 24 | -89.7% | 10.3% |
| Q4 25 | -14.6% | 13.4% | ||
| Q3 25 | -27.6% | 13.5% | ||
| Q2 25 | -32.0% | 10.5% | ||
| Q1 25 | -48.9% | 12.2% | ||
| Q4 24 | -63.1% | 10.3% | ||
| Q3 24 | -61.7% | 14.3% | ||
| Q2 24 | -91.0% | 11.7% | ||
| Q1 24 | -91.1% | 12.0% |
| Q4 25 | $-0.55 | $0.69 | ||
| Q3 25 | $-0.94 | $0.67 | ||
| Q2 25 | $-0.97 | $0.52 | ||
| Q1 25 | $-1.22 | $0.58 | ||
| Q4 24 | $-1.54 | $0.46 | ||
| Q3 24 | $-1.34 | $0.62 | ||
| Q2 24 | $-1.67 | $0.48 | ||
| Q1 24 | $-1.44 | $0.48 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $322.9M | $151.4M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $88.3M | $973.9M |
| Total Assets | $689.8M | $1.2B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $322.9M | $151.4M | ||
| Q3 25 | $325.3M | $133.7M | ||
| Q2 25 | $303.0M | $107.6M | ||
| Q1 25 | $300.9M | $94.9M | ||
| Q4 24 | $315.4M | $241.0M | ||
| Q3 24 | $327.3M | $205.8M | ||
| Q2 24 | $315.7M | $271.8M | ||
| Q1 24 | $331.4M | $290.8M |
| Q4 25 | $88.3M | $973.9M | ||
| Q3 25 | $73.7M | $958.9M | ||
| Q2 25 | $73.1M | $949.8M | ||
| Q1 25 | $53.2M | $920.9M | ||
| Q4 24 | $57.0M | $854.7M | ||
| Q3 24 | $92.9M | $829.4M | ||
| Q2 24 | $102.9M | $703.4M | ||
| Q1 24 | $144.0M | $683.0M |
| Q4 25 | $689.8M | $1.2B | ||
| Q3 25 | $669.3M | $1.2B | ||
| Q2 25 | $639.8M | $1.1B | ||
| Q1 25 | $596.7M | $1.1B | ||
| Q4 24 | $568.5M | $1.0B | ||
| Q3 24 | $561.5M | $1.0B | ||
| Q2 24 | $548.2M | $854.5M | ||
| Q1 24 | $545.7M | $839.8M |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-18.7M | $45.9M |
| Free Cash FlowOCF − Capex | $-18.7M | $38.2M |
| FCF MarginFCF / Revenue | -9.6% | 19.8% |
| Capex IntensityCapex / Revenue | 0.0% | 4.0% |
| Cash ConversionOCF / Net Profit | — | 1.78× |
| TTM Free Cash FlowTrailing 4 quarters | $-93.9M | $152.3M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-18.7M | $45.9M | ||
| Q3 25 | $1.0M | $60.6M | ||
| Q2 25 | $-32.4M | $32.3M | ||
| Q1 25 | $-43.4M | $40.0M | ||
| Q4 24 | $-26.2M | $40.6M | ||
| Q3 24 | $-18.6M | $53.3M | ||
| Q2 24 | $-30.1M | $29.4M | ||
| Q1 24 | $-53.5M | $34.1M |
| Q4 25 | $-18.7M | $38.2M | ||
| Q3 25 | $988.0K | $54.6M | ||
| Q2 25 | $-32.4M | $25.7M | ||
| Q1 25 | $-43.7M | $33.8M | ||
| Q4 24 | $-26.2M | $34.3M | ||
| Q3 24 | $-18.7M | $48.1M | ||
| Q2 24 | $-30.2M | $24.4M | ||
| Q1 24 | $-53.6M | $30.5M |
| Q4 25 | -9.6% | 19.8% | ||
| Q3 25 | 0.6% | 28.7% | ||
| Q2 25 | -21.6% | 13.7% | ||
| Q1 25 | -36.0% | 18.6% | ||
| Q4 24 | -22.1% | 20.1% | ||
| Q3 24 | -17.9% | 29.4% | ||
| Q2 24 | -34.6% | 15.9% | ||
| Q1 24 | -71.4% | 20.4% |
| Q4 25 | 0.0% | 4.0% | ||
| Q3 25 | 0.0% | 3.2% | ||
| Q2 25 | 0.0% | 3.6% | ||
| Q1 25 | 0.3% | 3.4% | ||
| Q4 24 | 0.0% | 3.6% | ||
| Q3 24 | 0.1% | 3.2% | ||
| Q2 24 | 0.1% | 3.3% | ||
| Q1 24 | 0.1% | 2.4% |
| Q4 25 | — | 1.78× | ||
| Q3 25 | — | 2.37× | ||
| Q2 25 | — | 1.64× | ||
| Q1 25 | — | 1.80× | ||
| Q4 24 | — | 2.31× | ||
| Q3 24 | — | 2.27× | ||
| Q2 24 | — | 1.63× | ||
| Q1 24 | — | 1.89× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
AXSM
Segment breakdown not available.
SPSC
| Recurring Revenues | $184.5M | 96% |
| One Time Revenues | $8.1M | 4% |
| Set Up Fees | $4.1M | 2% |
