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Side-by-side financial comparison of AYTU BIOPHARMA, INC (AYTU) and INNOVATIVE SOLUTIONS & SUPPORT INC (ISSC). Click either name above to swap in a different company.

INNOVATIVE SOLUTIONS & SUPPORT INC is the larger business by last-quarter revenue ($21.8M vs $15.2M, roughly 1.4× AYTU BIOPHARMA, INC). INNOVATIVE SOLUTIONS & SUPPORT INC runs the higher net margin — 18.6% vs -69.8%, a 88.4% gap on every dollar of revenue. On growth, INNOVATIVE SOLUTIONS & SUPPORT INC posted the faster year-over-year revenue change (36.6% vs -6.5%). INNOVATIVE SOLUTIONS & SUPPORT INC produced more free cash flow last quarter ($7.0M vs $3.7M). Over the past eight quarters, INNOVATIVE SOLUTIONS & SUPPORT INC's revenue compounded faster (42.5% CAGR vs 4.0%).

Aytu BioPharma, Inc. is a US-based specialty pharmaceutical company that develops and commercializes a portfolio of consumer healthcare products and prescription therapeutics. Its key offerings cover cold and allergy treatments, sexual health solutions, and therapies for rare pediatric conditions, serving patients and healthcare providers across the United States.

Motorola Solutions, Inc., is an American technology company that provides safety and security products and services. Headquartered in Chicago, Illinois, the company provides critical communications, video security, and command center technologies, used by public safety agencies and enterprises. It was formed in 2011 by the division of Motorola, Inc., and is its legal successor; the former company's mobile phone division was spun off as Motorola Mobility, now part of Chinese technology company...

AYTU vs ISSC — Head-to-Head

Bigger by revenue
ISSC
ISSC
1.4× larger
ISSC
$21.8M
$15.2M
AYTU
Growing faster (revenue YoY)
ISSC
ISSC
+43.1% gap
ISSC
36.6%
-6.5%
AYTU
Higher net margin
ISSC
ISSC
88.4% more per $
ISSC
18.6%
-69.8%
AYTU
More free cash flow
ISSC
ISSC
$3.4M more FCF
ISSC
$7.0M
$3.7M
AYTU
Faster 2-yr revenue CAGR
ISSC
ISSC
Annualised
ISSC
42.5%
4.0%
AYTU

Income Statement — Q2 FY2026 vs Q1 FY2026

Metric
AYTU
AYTU
ISSC
ISSC
Revenue
$15.2M
$21.8M
Net Profit
$-10.6M
$4.1M
Gross Margin
63.5%
54.5%
Operating Margin
-13.0%
28.9%
Net Margin
-69.8%
18.6%
Revenue YoY
-6.5%
36.6%
Net Profit YoY
-1443.1%
451.4%
EPS (diluted)
$-1.05
$0.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
AYTU
AYTU
ISSC
ISSC
Q4 25
$15.2M
$21.8M
Q3 25
$13.9M
$22.2M
Q2 25
$15.1M
$24.1M
Q1 25
$18.5M
$21.9M
Q4 24
$16.2M
$16.0M
Q3 24
$16.6M
$15.4M
Q2 24
$14.6M
$11.8M
Q1 24
$14.0M
$10.7M
Net Profit
AYTU
AYTU
ISSC
ISSC
Q4 25
$-10.6M
$4.1M
Q3 25
$2.0M
$7.1M
Q2 25
$-19.8M
$2.4M
Q1 25
$4.0M
$5.3M
Q4 24
$788.0K
$736.2K
Q3 24
$1.5M
$3.2M
Q2 24
$-4.6M
$1.6M
Q1 24
$-2.9M
$1.2M
Gross Margin
AYTU
AYTU
ISSC
ISSC
Q4 25
63.5%
54.5%
Q3 25
66.1%
63.2%
Q2 25
67.8%
35.5%
Q1 25
69.4%
51.4%
Q4 24
66.5%
41.4%
Q3 24
72.3%
55.4%
Q2 24
75.7%
53.4%
Q1 24
73.9%
52.0%
Operating Margin
AYTU
AYTU
ISSC
ISSC
Q4 25
-13.0%
28.9%
Q3 25
-10.8%
37.0%
Q2 25
-50.4%
14.6%
Q1 25
13.1%
31.8%
Q4 24
-10.4%
8.4%
Q3 24
-5.6%
28.4%
Q2 24
-15.6%
17.3%
Q1 24
-11.4%
15.3%
Net Margin
AYTU
AYTU
ISSC
ISSC
Q4 25
-69.8%
18.6%
Q3 25
14.1%
32.0%
Q2 25
-130.9%
10.1%
Q1 25
21.6%
24.3%
Q4 24
4.9%
4.6%
Q3 24
8.9%
20.7%
Q2 24
-31.6%
13.2%
Q1 24
-20.6%
11.3%
EPS (diluted)
AYTU
AYTU
ISSC
ISSC
Q4 25
$-1.05
$0.22
Q3 25
$-0.08
$0.40
Q2 25
$0.14
Q1 25
$0.21
$0.30
Q4 24
$-0.26
$0.04
Q3 24
$-0.15
$0.18
Q2 24
$0.09
Q1 24
$-0.52
$0.07

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
AYTU
AYTU
ISSC
ISSC
Cash + ST InvestmentsLiquidity on hand
$30.0M
$8.3M
Total DebtLower is stronger
$10.0M
$23.8M
Stockholders' EquityBook value
$14.2M
$68.7M
Total Assets
$122.0M
$109.9M
Debt / EquityLower = less leverage
0.70×
0.35×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
AYTU
AYTU
ISSC
ISSC
Q4 25
$30.0M
$8.3M
Q3 25
$32.6M
$2.7M
Q2 25
$31.0M
$601.8K
Q1 25
$18.2M
$1.2M
Q4 24
$20.4M
$604.6K
Q3 24
$20.1M
$539.0K
Q2 24
$20.0M
$521.0K
Q1 24
$19.8M
$574.1K
Total Debt
AYTU
AYTU
ISSC
ISSC
Q4 25
$10.0M
$23.8M
Q3 25
$10.4M
$24.4M
Q2 25
$10.9M
Q1 25
$9.5M
Q4 24
$10.0M
Q3 24
$10.4M
Q2 24
$10.9M
Q1 24
$0
Stockholders' Equity
AYTU
AYTU
ISSC
ISSC
Q4 25
$14.2M
$68.7M
Q3 25
$23.2M
$64.6M
Q2 25
$19.0M
$56.8M
Q1 25
$34.9M
$53.5M
Q4 24
$30.8M
$47.8M
Q3 24
$29.8M
$46.6M
Q2 24
$27.7M
$43.2M
Q1 24
$30.8M
$41.4M
Total Assets
AYTU
AYTU
ISSC
ISSC
Q4 25
$122.0M
$109.9M
Q3 25
$125.0M
$103.4M
Q2 25
$124.2M
$91.8M
Q1 25
$124.2M
$89.9M
Q4 24
$116.2M
$81.3M
Q3 24
$115.8M
$82.4M
Q2 24
$118.1M
$59.8M
Q1 24
$128.9M
$57.6M
Debt / Equity
AYTU
AYTU
ISSC
ISSC
Q4 25
0.70×
0.35×
Q3 25
0.45×
0.38×
Q2 25
0.57×
Q1 25
0.27×
Q4 24
0.32×
Q3 24
0.35×
Q2 24
0.39×
Q1 24
0.00×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
AYTU
AYTU
ISSC
ISSC
Operating Cash FlowLast quarter
$3.7M
$8.2M
Free Cash FlowOCF − Capex
$3.7M
$7.0M
FCF MarginFCF / Revenue
24.1%
32.3%
Capex IntensityCapex / Revenue
0.1%
5.1%
Cash ConversionOCF / Net Profit
2.01×
TTM Free Cash FlowTrailing 4 quarters
$12.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
AYTU
AYTU
ISSC
ISSC
Q4 25
$3.7M
$8.2M
Q3 25
$-618.0K
$3.0M
Q2 25
$2.8M
$7.2M
Q1 25
$-6.5M
$1.3M
Q4 24
$2.9M
$1.8M
Q3 24
$-1.2M
$445.3K
Q2 24
$-788.0K
$934.1K
Q1 24
$-254.0K
$201.1K
Free Cash Flow
AYTU
AYTU
ISSC
ISSC
Q4 25
$3.7M
$7.0M
Q3 25
$2.0M
Q2 25
$3.5M
Q1 25
$-6.5M
$-267.7K
Q4 24
$2.9M
$1.6M
Q3 24
$-1.3M
$299.5K
Q2 24
$730.8K
Q1 24
$75.4K
FCF Margin
AYTU
AYTU
ISSC
ISSC
Q4 25
24.1%
32.3%
Q3 25
8.8%
Q2 25
14.6%
Q1 25
-35.4%
-1.2%
Q4 24
17.9%
9.9%
Q3 24
-8.0%
1.9%
Q2 24
6.2%
Q1 24
0.7%
Capex Intensity
AYTU
AYTU
ISSC
ISSC
Q4 25
0.1%
5.1%
Q3 25
0.0%
4.5%
Q2 25
15.3%
Q1 25
0.4%
7.1%
Q4 24
0.0%
1.6%
Q3 24
0.8%
0.9%
Q2 24
1.7%
Q1 24
0.0%
1.2%
Cash Conversion
AYTU
AYTU
ISSC
ISSC
Q4 25
2.01×
Q3 25
-0.31×
0.42×
Q2 25
2.95×
Q1 25
-1.62×
0.24×
Q4 24
3.69×
2.50×
Q3 24
-0.81×
0.14×
Q2 24
0.60×
Q1 24
0.17×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

AYTU
AYTU

Segment breakdown not available.

ISSC
ISSC

Products$13.6M62%
Services$8.2M38%

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