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Side-by-side financial comparison of BICYCLE THERAPEUTICS PLC (BCYC) and LZ Technology Holdings Ltd (LZMH). Click either name above to swap in a different company.

LZ Technology Holdings Ltd is the larger business by last-quarter revenue ($57.8M vs $48.0M, roughly 1.2× BICYCLE THERAPEUTICS PLC). LZ Technology Holdings Ltd runs the higher net margin — -10.5% vs -42.0%, a 31.6% gap on every dollar of revenue. LZ Technology Holdings Ltd produced more free cash flow last quarter ($-6.8M vs $-19.9M).

Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical firm developing innovative bicyclic peptide therapies for unmet medical needs. Its core pipeline covers oncology, rare diseases, and immunological disorders, with operations in Europe and North America, and partnerships with global pharma leaders to advance drug candidates to market.

BCYC vs LZMH — Head-to-Head

Bigger by revenue
LZMH
LZMH
1.2× larger
LZMH
$57.8M
$48.0M
BCYC
Higher net margin
LZMH
LZMH
31.6% more per $
LZMH
-10.5%
-42.0%
BCYC
More free cash flow
LZMH
LZMH
$13.2M more FCF
LZMH
$-6.8M
$-19.9M
BCYC

Income Statement — Q4 FY2025 vs Q2 FY2025

Metric
BCYC
BCYC
LZMH
LZMH
Revenue
$48.0M
$57.8M
Net Profit
$-20.2M
$-6.0M
Gross Margin
3.0%
Operating Margin
-51.5%
-10.1%
Net Margin
-42.0%
-10.5%
Revenue YoY
1193.3%
Net Profit YoY
61.1%
EPS (diluted)
$-0.29
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BCYC
BCYC
LZMH
LZMH
Q4 25
$48.0M
Q3 25
$11.7M
Q2 25
$2.9M
$57.8M
Q1 25
$10.0M
Q4 24
$3.7M
Q3 24
$2.7M
Q2 24
$9.4M
Q1 24
$19.5M
Net Profit
BCYC
BCYC
LZMH
LZMH
Q4 25
$-20.2M
Q3 25
$-59.1M
Q2 25
$-79.0M
$-6.0M
Q1 25
$-60.8M
Q4 24
Q3 24
$-50.8M
Q2 24
$-39.8M
Q1 24
$-26.6M
Gross Margin
BCYC
BCYC
LZMH
LZMH
Q4 25
Q3 25
Q2 25
3.0%
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Operating Margin
BCYC
BCYC
LZMH
LZMH
Q4 25
-51.5%
Q3 25
-558.6%
Q2 25
-2965.8%
-10.1%
Q1 25
-703.7%
Q4 24
Q3 24
-2385.9%
Q2 24
-498.3%
Q1 24
-162.4%
Net Margin
BCYC
BCYC
LZMH
LZMH
Q4 25
-42.0%
Q3 25
-503.7%
Q2 25
-2703.8%
-10.5%
Q1 25
-608.9%
Q4 24
Q3 24
-1898.4%
Q2 24
-425.3%
Q1 24
-136.0%
EPS (diluted)
BCYC
BCYC
LZMH
LZMH
Q4 25
$-0.29
Q3 25
$-0.85
Q2 25
$-1.14
$-0.04
Q1 25
$-0.88
Q4 24
Q3 24
$-0.74
Q2 24
$-0.77
Q1 24
$-0.62

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BCYC
BCYC
LZMH
LZMH
Cash + ST InvestmentsLiquidity on hand
$628.1M
$2.2M
Total DebtLower is stronger
Stockholders' EquityBook value
$610.0M
$9.5M
Total Assets
$717.6M
$71.5M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BCYC
BCYC
LZMH
LZMH
Q4 25
$628.1M
Q3 25
$648.3M
Q2 25
$721.5M
$2.2M
Q1 25
$793.0M
Q4 24
$879.5M
Q3 24
$890.9M
Q2 24
$961.4M
Q1 24
$457.0M
Total Debt
BCYC
BCYC
LZMH
LZMH
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
$30.9M
Q1 24
$30.8M
Stockholders' Equity
BCYC
BCYC
LZMH
LZMH
Q4 25
$610.0M
Q3 25
$618.5M
Q2 25
$668.9M
$9.5M
Q1 25
$740.3M
Q4 24
$793.1M
Q3 24
$831.0M
Q2 24
$873.8M
Q1 24
$356.0M
Total Assets
BCYC
BCYC
LZMH
LZMH
Q4 25
$717.6M
Q3 25
$764.0M
Q2 25
$832.2M
$71.5M
Q1 25
$883.9M
Q4 24
$956.9M
Q3 24
$996.7M
Q2 24
$1.1B
Q1 24
$547.1M
Debt / Equity
BCYC
BCYC
LZMH
LZMH
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
0.04×
Q1 24
0.09×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BCYC
BCYC
LZMH
LZMH
Operating Cash FlowLast quarter
$-19.3M
$-6.7M
Free Cash FlowOCF − Capex
$-19.9M
$-6.8M
FCF MarginFCF / Revenue
-41.5%
-11.7%
Capex IntensityCapex / Revenue
1.2%
0.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-252.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BCYC
BCYC
LZMH
LZMH
Q4 25
$-19.3M
Q3 25
$-71.2M
Q2 25
$-72.8M
$-6.7M
Q1 25
$-86.4M
Q4 24
$-164.7M
Q3 24
$-39.8M
Q2 24
$-44.6M
Q1 24
$-70.9M
Free Cash Flow
BCYC
BCYC
LZMH
LZMH
Q4 25
$-19.9M
Q3 25
$-71.8M
Q2 25
$-73.3M
$-6.8M
Q1 25
$-87.0M
Q4 24
$-166.0M
Q3 24
$-40.3M
Q2 24
$-45.0M
Q1 24
$-70.9M
FCF Margin
BCYC
BCYC
LZMH
LZMH
Q4 25
-41.5%
Q3 25
-612.3%
Q2 25
-2509.7%
-11.7%
Q1 25
-871.7%
Q4 24
-4475.7%
Q3 24
-1504.7%
Q2 24
-481.2%
Q1 24
-362.9%
Capex Intensity
BCYC
BCYC
LZMH
LZMH
Q4 25
1.2%
Q3 25
5.7%
Q2 25
17.1%
0.0%
Q1 25
6.1%
Q4 24
33.3%
Q3 24
16.3%
Q2 24
4.5%
Q1 24
0.1%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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