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Side-by-side financial comparison of BIO-RAD LABORATORIES, INC. (BIO) and HARVARD BIOSCIENCE INC (HBIO). Click either name above to swap in a different company.

BIO-RAD LABORATORIES, INC. is the larger business by last-quarter revenue ($693.2M vs $23.7M, roughly 29.2× HARVARD BIOSCIENCE INC). BIO-RAD LABORATORIES, INC. runs the higher net margin — 103.9% vs -12.0%, a 115.9% gap on every dollar of revenue. On growth, BIO-RAD LABORATORIES, INC. posted the faster year-over-year revenue change (3.9% vs -3.3%). BIO-RAD LABORATORIES, INC. produced more free cash flow last quarter ($119.1M vs $-545.0K). Over the past eight quarters, BIO-RAD LABORATORIES, INC.'s revenue compounded faster (6.5% CAGR vs -1.6%).

Bio-Rad Laboratories, Inc. is an American developer and manufacturer of specialized technological products for the life science research and clinical diagnostics markets. The company was founded in 1952 in Berkeley, California, by husband and wife team David and Alice Schwartz, both graduates of the University of California, Berkeley. Bio-Rad is based in Hercules, California, and has operations worldwide.

Harvard Bioscience is a global developer, manufacturer and marketer of life sciences equipment to support research and drug discovery. It is traded on NASDAQ under the stock symbol HBIO.

BIO vs HBIO — Head-to-Head

Bigger by revenue
BIO
BIO
29.2× larger
BIO
$693.2M
$23.7M
HBIO
Growing faster (revenue YoY)
BIO
BIO
+7.2% gap
BIO
3.9%
-3.3%
HBIO
Higher net margin
BIO
BIO
115.9% more per $
BIO
103.9%
-12.0%
HBIO
More free cash flow
BIO
BIO
$119.6M more FCF
BIO
$119.1M
$-545.0K
HBIO
Faster 2-yr revenue CAGR
BIO
BIO
Annualised
BIO
6.5%
-1.6%
HBIO

Income Statement — Q4 2025 vs Q4 2025

Metric
BIO
BIO
HBIO
HBIO
Revenue
$693.2M
$23.7M
Net Profit
$720.0M
$-2.8M
Gross Margin
49.8%
59.7%
Operating Margin
-17.2%
7.2%
Net Margin
103.9%
-12.0%
Revenue YoY
3.9%
-3.3%
Net Profit YoY
200.6%
-15916.7%
EPS (diluted)
$26.59
$-0.06

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BIO
BIO
HBIO
HBIO
Q4 25
$693.2M
$23.7M
Q3 25
$653.0M
$20.6M
Q2 25
$651.6M
$20.4M
Q1 25
$585.4M
$21.8M
Q4 24
$667.5M
$24.6M
Q3 24
$649.7M
$22.0M
Q2 24
$638.5M
$23.1M
Q1 24
$610.8M
$24.5M
Net Profit
BIO
BIO
HBIO
HBIO
Q4 25
$720.0M
$-2.8M
Q3 25
$-341.9M
$-1.2M
Q2 25
$317.8M
$-2.3M
Q1 25
$64.0M
$-50.3M
Q4 24
$-715.8M
$18.0K
Q3 24
$653.2M
$-4.8M
Q2 24
$-2.2B
$-2.9M
Q1 24
$383.9M
$-4.7M
Gross Margin
BIO
BIO
HBIO
HBIO
Q4 25
49.8%
59.7%
Q3 25
52.6%
58.4%
Q2 25
53.0%
56.4%
Q1 25
52.3%
56.0%
Q4 24
51.2%
57.1%
Q3 24
54.8%
58.1%
Q2 24
55.6%
57.2%
Q1 24
53.4%
60.3%
Operating Margin
BIO
BIO
HBIO
HBIO
Q4 25
-17.2%
7.2%
Q3 25
10.0%
1.0%
Q2 25
11.8%
-4.0%
Q1 25
4.0%
-228.1%
Q4 24
8.7%
0.0%
Q3 24
9.9%
-8.5%
Q2 24
15.9%
-9.0%
Q1 24
7.3%
-9.3%
Net Margin
BIO
BIO
HBIO
HBIO
Q4 25
103.9%
-12.0%
Q3 25
-52.4%
-6.0%
Q2 25
48.8%
-11.2%
Q1 25
10.9%
-231.2%
Q4 24
-107.2%
0.1%
Q3 24
100.5%
-21.9%
Q2 24
-339.2%
-12.7%
Q1 24
62.9%
-19.1%
EPS (diluted)
BIO
BIO
HBIO
HBIO
Q4 25
$26.59
$-0.06
Q3 25
$-12.70
$-0.03
Q2 25
$11.67
$-0.05
Q1 25
$2.29
$-1.14
Q4 24
$-25.89
$0.01
Q3 24
$23.34
$-0.11
Q2 24
$-76.26
$-0.07
Q1 24
$13.45
$-0.11

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BIO
BIO
HBIO
HBIO
Cash + ST InvestmentsLiquidity on hand
$1.5B
$8.6M
Total DebtLower is stronger
$1.2B
$35.9M
Stockholders' EquityBook value
$7.5B
$13.7M
Total Assets
$10.6B
$80.1M
Debt / EquityLower = less leverage
0.16×
2.61×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BIO
BIO
HBIO
HBIO
Q4 25
$1.5B
$8.6M
Q3 25
$1.4B
$6.8M
Q2 25
$1.4B
$7.4M
Q1 25
$1.7B
$5.5M
Q4 24
$1.7B
$4.1M
Q3 24
$1.6B
$4.6M
Q2 24
$1.6B
$4.0M
Q1 24
$1.6B
$4.3M
Total Debt
BIO
BIO
HBIO
HBIO
Q4 25
$1.2B
$35.9M
Q3 25
$1.2B
$34.0M
Q2 25
$34.9M
Q1 25
$36.4M
Q4 24
$1.2B
$37.0M
Q3 24
$34.9M
Q2 24
$35.7M
Q1 24
$35.6M
Stockholders' Equity
BIO
BIO
HBIO
HBIO
Q4 25
$7.5B
$13.7M
Q3 25
$6.7B
$14.1M
Q2 25
$7.1B
$15.7M
Q1 25
$6.7B
$14.8M
Q4 24
$6.6B
$63.3M
Q3 24
$7.5B
$65.3M
Q2 24
$6.8B
$67.2M
Q1 24
$9.1B
$68.8M
Total Assets
BIO
BIO
HBIO
HBIO
Q4 25
$10.6B
$80.1M
Q3 25
$9.7B
$78.0M
Q2 25
$10.2B
$80.1M
Q1 25
$9.5B
$79.8M
Q4 24
$9.4B
$126.6M
Q3 24
$10.6B
$131.2M
Q2 24
$9.7B
$128.9M
Q1 24
$12.6B
$133.2M
Debt / Equity
BIO
BIO
HBIO
HBIO
Q4 25
0.16×
2.61×
Q3 25
0.18×
2.41×
Q2 25
2.22×
Q1 25
2.45×
Q4 24
0.18×
0.58×
Q3 24
0.53×
Q2 24
0.53×
Q1 24
0.52×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BIO
BIO
HBIO
HBIO
Operating Cash FlowLast quarter
$164.9M
$-96.0K
Free Cash FlowOCF − Capex
$119.1M
$-545.0K
FCF MarginFCF / Revenue
17.2%
-2.3%
Capex IntensityCapex / Revenue
6.6%
1.9%
Cash ConversionOCF / Net Profit
0.23×
TTM Free Cash FlowTrailing 4 quarters
$374.6M
$5.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BIO
BIO
HBIO
HBIO
Q4 25
$164.9M
$-96.0K
Q3 25
$120.9M
$1.1M
Q2 25
$116.5M
$2.8M
Q1 25
$129.9M
$3.0M
Q4 24
$124.2M
$1.7M
Q3 24
$163.6M
$-842.0K
Q2 24
$97.6M
$-846.0K
Q1 24
$69.8M
$1.4M
Free Cash Flow
BIO
BIO
HBIO
HBIO
Q4 25
$119.1M
$-545.0K
Q3 25
$89.2M
$877.0K
Q2 25
$70.8M
$2.7M
Q1 25
$95.5M
$2.5M
Q4 24
$81.2M
$1.4M
Q3 24
$123.4M
$-1.7M
Q2 24
$55.4M
$-1.7M
Q1 24
$29.6M
$758.0K
FCF Margin
BIO
BIO
HBIO
HBIO
Q4 25
17.2%
-2.3%
Q3 25
13.7%
4.3%
Q2 25
10.9%
13.0%
Q1 25
16.3%
11.4%
Q4 24
12.2%
5.8%
Q3 24
19.0%
-7.8%
Q2 24
8.7%
-7.2%
Q1 24
4.8%
3.1%
Capex Intensity
BIO
BIO
HBIO
HBIO
Q4 25
6.6%
1.9%
Q3 25
4.9%
1.0%
Q2 25
7.0%
0.4%
Q1 25
5.9%
2.4%
Q4 24
6.4%
1.2%
Q3 24
6.2%
4.0%
Q2 24
6.6%
3.5%
Q1 24
6.6%
2.6%
Cash Conversion
BIO
BIO
HBIO
HBIO
Q4 25
0.23×
Q3 25
Q2 25
0.37×
Q1 25
2.03×
Q4 24
95.83×
Q3 24
0.25×
Q2 24
Q1 24
0.18×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

BIO
BIO

Clinical Diagnostics$425.3M61%
Life Science$267.9M39%

HBIO
HBIO

Instruments Equipment Software And Accessories$21.6M91%
Service Maintenance And Warranty Contracts$2.1M9%

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