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Side-by-side financial comparison of BIOLIFE SOLUTIONS INC (BLFS) and NexPoint Real Estate Finance, Inc. (NREF). Click either name above to swap in a different company.

BIOLIFE SOLUTIONS INC is the larger business by last-quarter revenue ($18.8M vs $11.1M, roughly 1.7× NexPoint Real Estate Finance, Inc.). NexPoint Real Estate Finance, Inc. runs the higher net margin — 216.6% vs 58.9%, a 157.7% gap on every dollar of revenue. On growth, BIOLIFE SOLUTIONS INC posted the faster year-over-year revenue change (24.3% vs -48.8%).

Biolife Solutions Inc. develops, manufactures and distributes specialized biopreservation products and cold chain management solutions for the cell and gene therapy, biopharmaceutical and regenerative medicine industries. It offers cryopreservation media, automated thawing systems, and temperature monitoring tools, serving biotech firms, research institutions and clinical labs globally.

NexPoint Real Estate Finance, Inc. is a US-based commercial real estate finance firm that offers structured financing solutions for multifamily, office, industrial, and hospitality properties. It focuses on originating, managing and servicing a diversified portfolio of mortgage loans and real estate-related investments to deliver stable risk-adjusted returns to stakeholders.

BLFS vs NREF — Head-to-Head

Bigger by revenue
BLFS
BLFS
1.7× larger
BLFS
$18.8M
$11.1M
NREF
Growing faster (revenue YoY)
BLFS
BLFS
+73.2% gap
BLFS
24.3%
-48.8%
NREF
Higher net margin
NREF
NREF
157.7% more per $
NREF
216.6%
58.9%
BLFS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
BLFS
BLFS
NREF
NREF
Revenue
$18.8M
$11.1M
Net Profit
$11.1M
$24.0M
Gross Margin
Operating Margin
7.2%
Net Margin
58.9%
216.6%
Revenue YoY
24.3%
-48.8%
Net Profit YoY
-11.1%
58.7%
EPS (diluted)
$0.23
$0.47

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
BLFS
BLFS
NREF
NREF
Q4 25
$18.8M
$11.1M
Q3 25
$28.1M
$12.5M
Q2 25
$25.4M
$12.1M
Q1 25
$23.9M
$11.5M
Q4 24
$15.1M
$21.7M
Q3 24
$21.4M
$12.5M
Q2 24
$19.7M
$6.7M
Q1 24
$18.4M
$-12.8M
Net Profit
BLFS
BLFS
NREF
NREF
Q4 25
$11.1M
$24.0M
Q3 25
$621.0K
$50.9M
Q2 25
$-15.8M
$22.3M
Q1 25
$-448.0K
$26.0M
Q4 24
$12.5M
$15.2M
Q3 24
$-1.7M
$23.3M
Q2 24
$-20.7M
$12.1M
Q1 24
$-10.2M
$-14.6M
Operating Margin
BLFS
BLFS
NREF
NREF
Q4 25
7.2%
Q3 25
-0.3%
Q2 25
-65.5%
Q1 25
-5.1%
Q4 24
3.6%
Q3 24
-2.0%
Q2 24
-6.6%
Q1 24
-17.9%
Net Margin
BLFS
BLFS
NREF
NREF
Q4 25
58.9%
216.6%
Q3 25
2.2%
407.0%
Q2 25
-62.3%
184.5%
Q1 25
-1.9%
225.6%
Q4 24
82.5%
69.9%
Q3 24
-8.0%
186.4%
Q2 24
-105.1%
179.7%
Q1 24
-55.4%
114.3%
EPS (diluted)
BLFS
BLFS
NREF
NREF
Q4 25
$0.23
$0.47
Q3 25
$0.01
$1.14
Q2 25
$-0.33
$0.54
Q1 25
$-0.01
$0.70
Q4 24
$0.27
$0.71
Q3 24
$-0.04
$0.74
Q2 24
$-0.45
$0.40
Q1 24
$-0.22
$-0.83

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
BLFS
BLFS
NREF
NREF
Cash + ST InvestmentsLiquidity on hand
$33.0M
$31.1M
Total DebtLower is stronger
$5.0M
$771.2M
Stockholders' EquityBook value
$371.9M
$388.0M
Total Assets
$405.9M
$5.3B
Debt / EquityLower = less leverage
0.01×
1.99×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
BLFS
BLFS
NREF
NREF
Q4 25
$33.0M
$31.1M
Q3 25
$29.5M
$17.9M
Q2 25
$31.9M
$9.1M
Q1 25
$66.9M
$19.2M
Q4 24
$91.5M
$3.9M
Q3 24
$24.0M
$34.7M
Q2 24
$22.0M
$4.3M
Q1 24
$29.7M
$13.5M
Total Debt
BLFS
BLFS
NREF
NREF
Q4 25
$5.0M
$771.2M
Q3 25
$7.5M
$720.9M
Q2 25
$10.1M
$815.6M
Q1 25
$12.9M
$831.5M
Q4 24
$15.9M
$799.3M
Q3 24
$20.1M
$815.5M
Q2 24
$21.1M
$861.0M
Q1 24
$24.3M
$843.3M
Stockholders' Equity
BLFS
BLFS
NREF
NREF
Q4 25
$371.9M
$388.0M
Q3 25
$353.7M
$375.4M
Q2 25
$347.2M
$348.2M
Q1 25
$352.6M
$343.7M
Q4 24
$348.9M
$336.5M
Q3 24
$325.5M
$335.8M
Q2 24
$321.4M
$327.5M
Q1 24
$333.4M
$327.1M
Total Assets
BLFS
BLFS
NREF
NREF
Q4 25
$405.9M
$5.3B
Q3 25
$392.1M
$5.3B
Q2 25
$387.2M
$5.4B
Q1 25
$395.1M
$5.4B
Q4 24
$399.5M
$5.4B
Q3 24
$381.7M
$5.7B
Q2 24
$375.0M
$6.6B
Q1 24
$401.6M
$7.1B
Debt / Equity
BLFS
BLFS
NREF
NREF
Q4 25
0.01×
1.99×
Q3 25
0.02×
1.92×
Q2 25
0.03×
2.34×
Q1 25
0.04×
2.42×
Q4 24
0.05×
2.38×
Q3 24
0.06×
2.43×
Q2 24
0.07×
2.63×
Q1 24
0.07×
2.58×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
BLFS
BLFS
NREF
NREF
Operating Cash FlowLast quarter
$4.9M
$-4.5M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
0.44×
-0.19×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
BLFS
BLFS
NREF
NREF
Q4 25
$4.9M
$-4.5M
Q3 25
$6.1M
$8.1M
Q2 25
$7.4M
$3.3M
Q1 25
$1.7M
$16.0M
Q4 24
$1.6M
$4.4M
Q3 24
$4.8M
$14.7M
Q2 24
$6.5M
$-7.5M
Q1 24
$-4.5M
$17.7M
Cash Conversion
BLFS
BLFS
NREF
NREF
Q4 25
0.44×
-0.19×
Q3 25
9.83×
0.16×
Q2 25
0.15×
Q1 25
0.62×
Q4 24
0.13×
0.29×
Q3 24
0.63×
Q2 24
-0.62×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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