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Side-by-side financial comparison of Caris Life Sciences, Inc. (CAI) and MEDICAL PROPERTIES TRUST INC (MPW). Click either name above to swap in a different company.

MEDICAL PROPERTIES TRUST INC is the larger business by last-quarter revenue ($270.3M vs $216.8M, roughly 1.2× Caris Life Sciences, Inc.). Caris Life Sciences, Inc. runs the higher net margin — 11.2% vs 6.5%, a 4.7% gap on every dollar of revenue. On growth, Caris Life Sciences, Inc. posted the faster year-over-year revenue change (113.4% vs 16.6%).

Caris Life Sciences is a leading precision medicine biotech company specializing in advanced molecular profiling for oncology. It provides actionable genomic and molecular insights to oncologists to personalize cancer treatment plans, and partners with biopharmaceutical firms to accelerate novel cancer drug discovery and development, serving customers across North America, Europe, and key Asia-Pacific markets.

Medical Properties Trust, Inc. (MPT) is an international real estate investment trust (REIT) based in Birmingham, Alabama that purchases and invests in healthcare facilities and for-profit healthcare holding companies, primarily in the United States and Europe. Their property acquisitions often come in the form of sale-leaseback agreements, in which the original property owner sells the property to MPT and becomes their tenant. MPT's tenants are generally subject to long-term triple net lease...

CAI vs MPW — Head-to-Head

Bigger by revenue
MPW
MPW
1.2× larger
MPW
$270.3M
$216.8M
CAI
Growing faster (revenue YoY)
CAI
CAI
+96.8% gap
CAI
113.4%
16.6%
MPW
Higher net margin
CAI
CAI
4.7% more per $
CAI
11.2%
6.5%
MPW

Income Statement — Q3 FY2025 vs Q4 FY2025

Metric
CAI
CAI
MPW
MPW
Revenue
$216.8M
$270.3M
Net Profit
$24.3M
$17.6M
Gross Margin
95.8%
Operating Margin
15.1%
9.7%
Net Margin
11.2%
6.5%
Revenue YoY
113.4%
16.6%
Net Profit YoY
135.9%
104.3%
EPS (diluted)
$0.08
$0.03

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CAI
CAI
MPW
MPW
Q4 25
$270.3M
Q3 25
$216.8M
$237.5M
Q2 25
$181.4M
$240.4M
Q1 25
$223.8M
Q4 24
$231.8M
Q3 24
$101.6M
$225.8M
Q2 24
$100.0M
$266.6M
Q1 24
$271.3M
Net Profit
CAI
CAI
MPW
MPW
Q4 25
$17.6M
Q3 25
$24.3M
$-77.7M
Q2 25
$-71.8M
$-98.4M
Q1 25
$-118.3M
Q4 24
$-412.3M
Q3 24
$-67.7M
$-801.2M
Q2 24
$-66.2M
$-320.6M
Q1 24
$-875.6M
Gross Margin
CAI
CAI
MPW
MPW
Q4 25
95.8%
Q3 25
Q2 25
91.8%
Q1 25
63.6%
Q4 24
90.9%
Q3 24
96.5%
Q2 24
98.4%
Q1 24
84.9%
Operating Margin
CAI
CAI
MPW
MPW
Q4 25
9.7%
Q3 25
15.1%
-28.0%
Q2 25
-9.9%
-36.7%
Q1 25
-48.5%
Q4 24
-173.7%
Q3 24
-59.9%
-350.7%
Q2 24
-67.0%
-114.5%
Q1 24
-318.6%
Net Margin
CAI
CAI
MPW
MPW
Q4 25
6.5%
Q3 25
11.2%
-32.7%
Q2 25
-39.6%
-40.9%
Q1 25
-52.8%
Q4 24
-177.8%
Q3 24
-66.6%
-354.8%
Q2 24
-66.2%
-120.3%
Q1 24
-322.7%
EPS (diluted)
CAI
CAI
MPW
MPW
Q4 25
$0.03
Q3 25
$0.08
$-0.13
Q2 25
$-7.97
$-0.16
Q1 25
$-0.20
Q4 24
$-0.68
Q3 24
$-2.59
$-1.34
Q2 24
$-2.54
$-0.54
Q1 24
$-1.46

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CAI
CAI
MPW
MPW
Cash + ST InvestmentsLiquidity on hand
$755.5M
$540.9M
Total DebtLower is stronger
$375.9M
$9.7B
Stockholders' EquityBook value
$478.4M
$4.6B
Total Assets
$984.6M
$15.0B
Debt / EquityLower = less leverage
0.79×
2.11×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CAI
CAI
MPW
MPW
Q4 25
$540.9M
Q3 25
$755.5M
$396.6M
Q2 25
$721.2M
$509.8M
Q1 25
$673.5M
Q4 24
$332.3M
Q3 24
$275.6M
Q2 24
$606.5M
Q1 24
$224.3M
Total Debt
CAI
CAI
MPW
MPW
Q4 25
$9.7B
Q3 25
$375.9M
$9.6B
Q2 25
$373.4M
$9.6B
Q1 25
$9.5B
Q4 24
$8.8B
Q3 24
$9.2B
Q2 24
$9.4B
Q1 24
$10.1B
Stockholders' Equity
CAI
CAI
MPW
MPW
Q4 25
$4.6B
Q3 25
$478.4M
$4.7B
Q2 25
$452.9M
$4.8B
Q1 25
$4.8B
Q4 24
$4.8B
Q3 24
$-2.4B
$5.4B
Q2 24
$-2.4B
$6.2B
Q1 24
$6.7B
Total Assets
CAI
CAI
MPW
MPW
Q4 25
$15.0B
Q3 25
$984.6M
$14.9B
Q2 25
$955.1M
$15.2B
Q1 25
$14.9B
Q4 24
$14.3B
Q3 24
$15.2B
Q2 24
$16.2B
Q1 24
$17.3B
Debt / Equity
CAI
CAI
MPW
MPW
Q4 25
2.11×
Q3 25
0.79×
2.06×
Q2 25
0.82×
2.00×
Q1 25
1.99×
Q4 24
1.83×
Q3 24
1.69×
Q2 24
1.51×
Q1 24
1.51×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CAI
CAI
MPW
MPW
Operating Cash FlowLast quarter
$62.4M
$230.8M
Free Cash FlowOCF − Capex
$55.3M
FCF MarginFCF / Revenue
25.5%
Capex IntensityCapex / Revenue
3.3%
Cash ConversionOCF / Net Profit
2.57×
13.11×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CAI
CAI
MPW
MPW
Q4 25
$230.8M
Q3 25
$62.4M
$18.6M
Q2 25
$51.7M
Q1 25
$384.0K
Q4 24
$245.5M
Q3 24
$59.2M
Q2 24
$35.3M
Q1 24
$74.3M
Free Cash Flow
CAI
CAI
MPW
MPW
Q4 25
Q3 25
$55.3M
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
FCF Margin
CAI
CAI
MPW
MPW
Q4 25
Q3 25
25.5%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Capex Intensity
CAI
CAI
MPW
MPW
Q4 25
Q3 25
3.3%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Cash Conversion
CAI
CAI
MPW
MPW
Q4 25
13.11×
Q3 25
2.57×
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CAI
CAI

Molecular Profiling Services$207.6M96%
Pharma Research And Development Services$9.2M4%

MPW
MPW

Segment breakdown not available.

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