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Side-by-side financial comparison of AVIS BUDGET GROUP, INC. (CAR) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.0B vs $2.7B, roughly 1.1× AVIS BUDGET GROUP, INC.). Vertex Pharmaceuticals runs the higher net margin — 34.5% vs -28.0%, a 62.6% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (7.8% vs -1.7%). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (6.3% CAGR vs 2.2%).

Avis Budget Group, Inc. is an American car rental agency holding company headquartered in Parsippany, New Jersey. It is the parent company of several brands including Avis Car Rental, Budget Rent a Car, Budget Truck Rental, Payless Car Rental, and Zipcar.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

CAR vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.1× larger
VRTX
$3.0B
$2.7B
CAR
Growing faster (revenue YoY)
VRTX
VRTX
+9.5% gap
VRTX
7.8%
-1.7%
CAR
Higher net margin
VRTX
VRTX
62.6% more per $
VRTX
34.5%
-28.0%
CAR
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
6.3%
2.2%
CAR

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
CAR
CAR
VRTX
VRTX
Revenue
$2.7B
$3.0B
Net Profit
$-747.0M
$1.0B
Gross Margin
86.8%
Operating Margin
-27.8%
38.1%
Net Margin
-28.0%
34.5%
Revenue YoY
-1.7%
7.8%
Net Profit YoY
61.8%
59.6%
EPS (diluted)
$-21.11
$4.02

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CAR
CAR
VRTX
VRTX
Q1 26
$3.0B
Q4 25
$2.7B
$3.2B
Q3 25
$3.5B
$3.1B
Q2 25
$3.0B
$3.0B
Q1 25
$2.4B
$2.8B
Q4 24
$2.7B
$2.9B
Q3 24
$3.5B
$2.8B
Q2 24
$3.0B
$2.6B
Net Profit
CAR
CAR
VRTX
VRTX
Q1 26
$1.0B
Q4 25
$-747.0M
$1.2B
Q3 25
$359.0M
$1.1B
Q2 25
$4.0M
$1.0B
Q1 25
$-505.0M
$646.3M
Q4 24
$-2.0B
$913.0M
Q3 24
$237.0M
$1.0B
Q2 24
$14.0M
$-3.6B
Gross Margin
CAR
CAR
VRTX
VRTX
Q1 26
86.8%
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Operating Margin
CAR
CAR
VRTX
VRTX
Q1 26
38.1%
Q4 25
-27.8%
37.8%
Q3 25
13.4%
38.6%
Q2 25
0.5%
38.8%
Q1 25
-27.9%
22.7%
Q4 24
-104.8%
35.2%
Q3 24
9.5%
40.3%
Q2 24
0.9%
-132.9%
Net Margin
CAR
CAR
VRTX
VRTX
Q1 26
34.5%
Q4 25
-28.0%
37.3%
Q3 25
10.2%
35.2%
Q2 25
0.1%
34.8%
Q1 25
-20.8%
23.3%
Q4 24
-72.3%
31.4%
Q3 24
6.8%
37.7%
Q2 24
0.5%
-135.8%
EPS (diluted)
CAR
CAR
VRTX
VRTX
Q1 26
$4.02
Q4 25
$-21.11
$4.64
Q3 25
$10.11
$4.20
Q2 25
$0.10
$3.99
Q1 25
$-14.35
$2.49
Q4 24
$-55.08
$3.62
Q3 24
$6.65
$4.01
Q2 24
$0.41
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CAR
CAR
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$519.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$-3.1B
$19.4B
Total Assets
$31.3B
$26.5B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CAR
CAR
VRTX
VRTX
Q1 26
Q4 25
$519.0M
$6.6B
Q3 25
$564.0M
$6.3B
Q2 25
$541.0M
$6.4B
Q1 25
$516.0M
$6.2B
Q4 24
$534.0M
$6.1B
Q3 24
$602.0M
$6.5B
Q2 24
$511.0M
$5.8B
Stockholders' Equity
CAR
CAR
VRTX
VRTX
Q1 26
$19.4B
Q4 25
$-3.1B
$18.7B
Q3 25
$-2.4B
$17.3B
Q2 25
$-2.7B
$17.2B
Q1 25
$-2.8B
$16.5B
Q4 24
$-2.3B
$16.4B
Q3 24
$-238.0M
$15.6B
Q2 24
$-490.0M
$14.8B
Total Assets
CAR
CAR
VRTX
VRTX
Q1 26
$26.5B
Q4 25
$31.3B
$25.6B
Q3 25
$32.5B
$24.9B
Q2 25
$32.4B
$24.0B
Q1 25
$29.0B
$22.9B
Q4 24
$29.0B
$22.5B
Q3 24
$32.7B
$22.2B
Q2 24
$33.9B
$20.1B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CAR
CAR
VRTX
VRTX
Operating Cash FlowLast quarter
$437.0M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CAR
CAR
VRTX
VRTX
Q1 26
Q4 25
$437.0M
$498.0M
Q3 25
$1.4B
$1.2B
Q2 25
$837.0M
$1.1B
Q1 25
$619.0M
$818.9M
Q4 24
$772.0M
$584.6M
Q3 24
$1.3B
$1.4B
Q2 24
$884.0M
$-3.8B
Free Cash Flow
CAR
CAR
VRTX
VRTX
Q1 26
Q4 25
$348.6M
Q3 25
$1.1B
Q2 25
$927.4M
Q1 25
$778.2M
Q4 24
$492.0M
Q3 24
$1.3B
Q2 24
$-3.8B
FCF Margin
CAR
CAR
VRTX
VRTX
Q1 26
Q4 25
10.9%
Q3 25
37.0%
Q2 25
31.3%
Q1 25
28.1%
Q4 24
16.9%
Q3 24
47.0%
Q2 24
-144.5%
Capex Intensity
CAR
CAR
VRTX
VRTX
Q1 26
Q4 25
4.7%
Q3 25
3.3%
Q2 25
4.9%
Q1 25
1.5%
Q4 24
3.2%
Q3 24
2.4%
Q2 24
2.6%
Cash Conversion
CAR
CAR
VRTX
VRTX
Q1 26
Q4 25
0.42×
Q3 25
3.91×
1.15×
Q2 25
209.25×
1.04×
Q1 25
1.27×
Q4 24
0.64×
Q3 24
5.37×
1.31×
Q2 24
63.14×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CAR
CAR

Avis$1.5B57%
Budget$979.0M37%
Other Brands$171.0M6%

VRTX
VRTX

TRIKAFTA/KAFTRIO$2.4B79%
ALYFTREK$424.4M14%
Other$135.9M5%
CASGEVY$42.9M1%
Vertex recorded$29.0M1%

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