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Side-by-side financial comparison of Cardio Diagnostics Holdings, Inc. (CDIO) and QuidelOrtho Corp (QDEL). Click either name above to swap in a different company.

QuidelOrtho Corp is the larger business by last-quarter revenue ($699.9M vs $3.6K, roughly 196877.6× Cardio Diagnostics Holdings, Inc.). On growth, QuidelOrtho Corp posted the faster year-over-year revenue change (-3.7% vs -21.2%). Cardio Diagnostics Holdings, Inc. produced more free cash flow last quarter ($-5.9M vs $-94.7M). Over the past eight quarters, QuidelOrtho Corp's revenue compounded faster (-2.9% CAGR vs -52.8%).

Cardio Diagnostics Holdings, Inc. is a precision cardiovascular healthcare company that develops and commercializes integrated genetic and epigenetic diagnostic tests for early detection of coronary heart disease, heart failure, and other cardiovascular conditions. It primarily serves healthcare providers, clinical laboratories, and patients across the United States, focusing on delivering accessible, personalized cardiovascular care solutions.

QuidelOrtho Corporation is an American manufacturer of diagnostic healthcare products that are sold worldwide.

CDIO vs QDEL — Head-to-Head

Bigger by revenue
QDEL
QDEL
196877.6× larger
QDEL
$699.9M
$3.6K
CDIO
Growing faster (revenue YoY)
QDEL
QDEL
+17.5% gap
QDEL
-3.7%
-21.2%
CDIO
More free cash flow
CDIO
CDIO
$88.8M more FCF
CDIO
$-5.9M
$-94.7M
QDEL
Faster 2-yr revenue CAGR
QDEL
QDEL
Annualised
QDEL
-2.9%
-52.8%
CDIO

Income Statement — Q4 2025 vs Q3 2026

Metric
CDIO
CDIO
QDEL
QDEL
Revenue
$3.6K
$699.9M
Net Profit
$-733.0M
Gross Margin
Operating Margin
-100.7%
Net Margin
-104.7%
Revenue YoY
-21.2%
-3.7%
Net Profit YoY
3.6%
-3583.4%
EPS (diluted)
$-10.78

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CDIO
CDIO
QDEL
QDEL
Q4 25
$3.6K
Q3 25
$2.9K
$699.9M
Q2 25
$7.5K
$613.9M
Q1 25
$940
$692.8M
Q4 24
$4.5K
$707.8M
Q3 24
$6.6K
$727.1M
Q2 24
$7.9K
$637.0M
Q1 24
$15.9K
$711.0M
Net Profit
CDIO
CDIO
QDEL
QDEL
Q4 25
Q3 25
$-1.7M
$-733.0M
Q2 25
$-1.7M
$-255.4M
Q1 25
$-1.6M
$-12.7M
Q4 24
$-178.4M
Q3 24
$-1.4M
$-19.9M
Q2 24
$-1.3M
$-147.7M
Q1 24
$-4.2M
$-1.7B
Operating Margin
CDIO
CDIO
QDEL
QDEL
Q4 25
Q3 25
-59950.9%
-100.7%
Q2 25
-22457.5%
-29.4%
Q1 25
-173463.8%
4.7%
Q4 24
-14.2%
Q3 24
-21412.9%
2.1%
Q2 24
-16295.6%
-18.4%
Q1 24
-26105.3%
-247.3%
Net Margin
CDIO
CDIO
QDEL
QDEL
Q4 25
Q3 25
-60053.8%
-104.7%
Q2 25
-22517.7%
-41.6%
Q1 25
-173943.0%
-1.8%
Q4 24
-25.2%
Q3 24
-21467.6%
-2.7%
Q2 24
-16365.9%
-23.2%
Q1 24
-26140.0%
-239.9%
EPS (diluted)
CDIO
CDIO
QDEL
QDEL
Q4 25
Q3 25
$-0.98
$-10.78
Q2 25
$-0.97
$-3.77
Q1 25
$-0.97
$-0.19
Q4 24
$-2.54
Q3 24
$-1.73
$-0.30
Q2 24
$-1.71
$-2.20
Q1 24
$-5.93
$-25.50

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CDIO
CDIO
QDEL
QDEL
Cash + ST InvestmentsLiquidity on hand
$98.1M
Total DebtLower is stronger
$2.5B
Stockholders' EquityBook value
$7.0M
$2.0B
Total Assets
$7.8M
$5.7B
Debt / EquityLower = less leverage
1.23×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CDIO
CDIO
QDEL
QDEL
Q4 25
Q3 25
$98.1M
Q2 25
$151.7M
Q1 25
$127.1M
Q4 24
$98.3M
Q3 24
$143.7M
Q2 24
$107.0M
Q1 24
$78.5M
Total Debt
CDIO
CDIO
QDEL
QDEL
Q4 25
Q3 25
$2.5B
Q2 25
$2.1B
Q1 25
$2.1B
Q4 24
$2.1B
Q3 24
$2.2B
Q2 24
$2.2B
Q1 24
$2.2B
Stockholders' Equity
CDIO
CDIO
QDEL
QDEL
Q4 25
$7.0M
Q3 25
$8.2M
$2.0B
Q2 25
$9.7M
$2.8B
Q1 25
$11.4M
$3.0B
Q4 24
$9.6M
$3.0B
Q3 24
$3.7M
$3.2B
Q2 24
$3.1M
$3.2B
Q1 24
$3.0M
$3.3B
Total Assets
CDIO
CDIO
QDEL
QDEL
Q4 25
$7.8M
Q3 25
$8.8M
$5.7B
Q2 25
$10.4M
$6.4B
Q1 25
$12.3M
$6.5B
Q4 24
$10.6M
$6.4B
Q3 24
$4.5M
$6.8B
Q2 24
$4.0M
$6.7B
Q1 24
$4.3M
$6.7B
Debt / Equity
CDIO
CDIO
QDEL
QDEL
Q4 25
Q3 25
1.23×
Q2 25
0.74×
Q1 25
0.70×
Q4 24
0.72×
Q3 24
0.68×
Q2 24
0.70×
Q1 24
0.68×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CDIO
CDIO
QDEL
QDEL
Operating Cash FlowLast quarter
$-5.7M
$-45.5M
Free Cash FlowOCF − Capex
$-5.9M
$-94.7M
FCF MarginFCF / Revenue
-166361.5%
-13.5%
Capex IntensityCapex / Revenue
5269.1%
7.0%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-10.5M
$-153.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CDIO
CDIO
QDEL
QDEL
Q4 25
$-5.7M
Q3 25
$-1.4M
$-45.5M
Q2 25
$-1.6M
$-46.8M
Q1 25
$-1.4M
$65.6M
Q4 24
$-5.0M
$63.7M
Q3 24
$-1.2M
$117.9M
Q2 24
$-1.2M
$-97.9M
Q1 24
$-1.2M
$-700.0K
Free Cash Flow
CDIO
CDIO
QDEL
QDEL
Q4 25
$-5.9M
Q3 25
$-1.6M
$-94.7M
Q2 25
$-1.6M
$-84.3M
Q1 25
$-1.4M
$9.4M
Q4 24
$-5.2M
$16.5M
Q3 24
$-1.2M
$71.4M
Q2 24
$-1.4M
$-133.2M
Q1 24
$-1.3M
$-66.8M
FCF Margin
CDIO
CDIO
QDEL
QDEL
Q4 25
-166361.5%
Q3 25
-54509.7%
-13.5%
Q2 25
-21273.1%
-13.7%
Q1 25
-149562.6%
1.4%
Q4 24
-115422.6%
2.3%
Q3 24
-17942.3%
9.8%
Q2 24
-17513.3%
-20.9%
Q1 24
-7866.9%
-9.4%
Capex Intensity
CDIO
CDIO
QDEL
QDEL
Q4 25
5269.1%
Q3 25
5703.5%
7.0%
Q2 25
250.1%
6.1%
Q1 25
615.6%
8.1%
Q4 24
4759.9%
6.7%
Q3 24
353.3%
6.4%
Q2 24
2133.4%
5.5%
Q1 24
125.5%
9.3%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CDIO
CDIO

Segment breakdown not available.

QDEL
QDEL

Labs$373.8M53%
Point Of Care$164.6M24%
Immunohematology$142.0M20%
Donor Screening$14.7M2%
Molecular Diagnostics$4.8M1%
Collaborative Arrangement Transaction With Party To Collaborative Arrangement$2.1M0%

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