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Side-by-side financial comparison of Cardio Diagnostics Holdings, Inc. (CDIO) and Alpha Teknova, Inc. (TKNO). Click either name above to swap in a different company.

Alpha Teknova, Inc. is the larger business by last-quarter revenue ($10.0M vs $3.6K, roughly 2808.4× Cardio Diagnostics Holdings, Inc.). On growth, Alpha Teknova, Inc. posted the faster year-over-year revenue change (7.8% vs -21.2%). Alpha Teknova, Inc. produced more free cash flow last quarter ($-810.0K vs $-5.9M). Over the past eight quarters, Alpha Teknova, Inc.'s revenue compounded faster (3.7% CAGR vs -52.8%).

Cardio Diagnostics Holdings, Inc. is a precision cardiovascular healthcare company that develops and commercializes integrated genetic and epigenetic diagnostic tests for early detection of coronary heart disease, heart failure, and other cardiovascular conditions. It primarily serves healthcare providers, clinical laboratories, and patients across the United States, focusing on delivering accessible, personalized cardiovascular care solutions.

Alpha Teknova, Inc. is a life sciences company that develops and manufactures specialized reagents, cell culture media, and custom laboratory solutions. It serves biopharmaceutical, molecular diagnostic, and academic research clients, primarily operating across the North American market to support drug discovery, diagnostic testing, and life science research workflows.

CDIO vs TKNO — Head-to-Head

Bigger by revenue
TKNO
TKNO
2808.4× larger
TKNO
$10.0M
$3.6K
CDIO
Growing faster (revenue YoY)
TKNO
TKNO
+29.0% gap
TKNO
7.8%
-21.2%
CDIO
More free cash flow
TKNO
TKNO
$5.1M more FCF
TKNO
$-810.0K
$-5.9M
CDIO
Faster 2-yr revenue CAGR
TKNO
TKNO
Annualised
TKNO
3.7%
-52.8%
CDIO

Income Statement — Q4 2025 vs Q4 2025

Metric
CDIO
CDIO
TKNO
TKNO
Revenue
$3.6K
$10.0M
Net Profit
$-4.8M
Gross Margin
32.5%
Operating Margin
-46.2%
Net Margin
-47.7%
Revenue YoY
-21.2%
7.8%
Net Profit YoY
3.6%
16.8%
EPS (diluted)
$-0.08

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CDIO
CDIO
TKNO
TKNO
Q4 25
$3.6K
$10.0M
Q3 25
$2.9K
$10.5M
Q2 25
$7.5K
$10.3M
Q1 25
$940
$9.8M
Q4 24
$4.5K
$9.3M
Q3 24
$6.6K
$9.6M
Q2 24
$7.9K
$9.6M
Q1 24
$15.9K
$9.3M
Net Profit
CDIO
CDIO
TKNO
TKNO
Q4 25
$-4.8M
Q3 25
$-1.7M
$-4.3M
Q2 25
$-1.7M
$-3.6M
Q1 25
$-1.6M
$-4.6M
Q4 24
$-5.7M
Q3 24
$-1.4M
$-7.6M
Q2 24
$-1.3M
$-5.4M
Q1 24
$-4.2M
$-8.1M
Gross Margin
CDIO
CDIO
TKNO
TKNO
Q4 25
32.5%
Q3 25
30.7%
Q2 25
38.7%
Q1 25
30.7%
Q4 24
23.0%
Q3 24
0.9%
Q2 24
29.2%
Q1 24
23.8%
Operating Margin
CDIO
CDIO
TKNO
TKNO
Q4 25
-46.2%
Q3 25
-59950.9%
-38.4%
Q2 25
-22457.5%
-32.9%
Q1 25
-173463.8%
-50.7%
Q4 24
-60.7%
Q3 24
-21412.9%
-77.6%
Q2 24
-16295.6%
-53.0%
Q1 24
-26105.3%
-86.0%
Net Margin
CDIO
CDIO
TKNO
TKNO
Q4 25
-47.7%
Q3 25
-60053.8%
-41.0%
Q2 25
-22517.7%
-34.7%
Q1 25
-173943.0%
-47.4%
Q4 24
-61.7%
Q3 24
-21467.6%
-79.0%
Q2 24
-16365.9%
-55.8%
Q1 24
-26140.0%
-87.2%
EPS (diluted)
CDIO
CDIO
TKNO
TKNO
Q4 25
$-0.08
Q3 25
$-0.98
$-0.08
Q2 25
$-0.97
$-0.07
Q1 25
$-0.97
$-0.09
Q4 24
$-0.09
Q3 24
$-1.73
$-0.15
Q2 24
$-1.71
$-0.13
Q1 24
$-5.93
$-0.20

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CDIO
CDIO
TKNO
TKNO
Cash + ST InvestmentsLiquidity on hand
$21.3M
Total DebtLower is stronger
$13.1M
Stockholders' EquityBook value
$7.0M
$68.8M
Total Assets
$7.8M
$103.6M
Debt / EquityLower = less leverage
0.19×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CDIO
CDIO
TKNO
TKNO
Q4 25
$21.3M
Q3 25
$22.1M
Q2 25
$24.0M
Q1 25
$26.3M
Q4 24
$30.4M
Q3 24
$31.7M
Q2 24
$18.6M
Q1 24
$21.6M
Total Debt
CDIO
CDIO
TKNO
TKNO
Q4 25
$13.1M
Q3 25
$13.1M
Q2 25
$13.0M
Q1 25
$13.0M
Q4 24
$9.4M
Q3 24
$10.9M
Q2 24
$12.3M
Q1 24
$13.2M
Stockholders' Equity
CDIO
CDIO
TKNO
TKNO
Q4 25
$7.0M
$68.8M
Q3 25
$8.2M
$72.7M
Q2 25
$9.7M
$76.1M
Q1 25
$11.4M
$78.6M
Q4 24
$9.6M
$82.4M
Q3 24
$3.7M
$87.3M
Q2 24
$3.1M
$78.9M
Q1 24
$3.0M
$83.4M
Total Assets
CDIO
CDIO
TKNO
TKNO
Q4 25
$7.8M
$103.6M
Q3 25
$8.8M
$107.6M
Q2 25
$10.4M
$110.5M
Q1 25
$12.3M
$114.0M
Q4 24
$10.6M
$118.8M
Q3 24
$4.5M
$124.1M
Q2 24
$4.0M
$115.4M
Q1 24
$4.3M
$120.8M
Debt / Equity
CDIO
CDIO
TKNO
TKNO
Q4 25
0.19×
Q3 25
0.18×
Q2 25
0.17×
Q1 25
0.17×
Q4 24
0.11×
Q3 24
0.12×
Q2 24
0.16×
Q1 24
0.16×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CDIO
CDIO
TKNO
TKNO
Operating Cash FlowLast quarter
$-5.7M
$-462.0K
Free Cash FlowOCF − Capex
$-5.9M
$-810.0K
FCF MarginFCF / Revenue
-166361.5%
-8.1%
Capex IntensityCapex / Revenue
5269.1%
3.5%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-10.5M
$-9.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CDIO
CDIO
TKNO
TKNO
Q4 25
$-5.7M
$-462.0K
Q3 25
$-1.4M
$-2.0M
Q2 25
$-1.6M
$-2.1M
Q1 25
$-1.4M
$-4.1M
Q4 24
$-5.0M
$-936.0K
Q3 24
$-1.2M
$-2.1M
Q2 24
$-1.2M
$-2.8M
Q1 24
$-1.2M
$-6.6M
Free Cash Flow
CDIO
CDIO
TKNO
TKNO
Q4 25
$-5.9M
$-810.0K
Q3 25
$-1.6M
$-2.4M
Q2 25
$-1.6M
$-2.3M
Q1 25
$-1.4M
$-4.3M
Q4 24
$-5.2M
$-1.5M
Q3 24
$-1.2M
$-2.4M
Q2 24
$-1.4M
$-3.0M
Q1 24
$-1.3M
$-6.7M
FCF Margin
CDIO
CDIO
TKNO
TKNO
Q4 25
-166361.5%
-8.1%
Q3 25
-54509.7%
-22.6%
Q2 25
-21273.1%
-22.4%
Q1 25
-149562.6%
-44.0%
Q4 24
-115422.6%
-16.2%
Q3 24
-17942.3%
-25.0%
Q2 24
-17513.3%
-30.7%
Q1 24
-7866.9%
-71.8%
Capex Intensity
CDIO
CDIO
TKNO
TKNO
Q4 25
5269.1%
3.5%
Q3 25
5703.5%
3.7%
Q2 25
250.1%
2.0%
Q1 25
615.6%
2.1%
Q4 24
4759.9%
6.1%
Q3 24
353.3%
3.5%
Q2 24
2133.4%
1.2%
Q1 24
125.5%
1.2%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CDIO
CDIO

Segment breakdown not available.

TKNO
TKNO

Lab Essentials$6.8M68%
Clinical Solutions$2.7M27%
Other$435.0K4%

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