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Side-by-side financial comparison of CULLEN/FROST BANKERS, INC. (CFR) and INTEGRA LIFESCIENCES HOLDINGS CORP (IART). Click either name above to swap in a different company.

CULLEN/FROST BANKERS, INC. is the larger business by last-quarter revenue ($580.9M vs $434.9M, roughly 1.3× INTEGRA LIFESCIENCES HOLDINGS CORP). On growth, CULLEN/FROST BANKERS, INC. posted the faster year-over-year revenue change (8.3% vs -1.7%). CULLEN/FROST BANKERS, INC. produced more free cash flow last quarter ($127.3M vs $-5.4M). Over the past eight quarters, INTEGRA LIFESCIENCES HOLDINGS CORP's revenue compounded faster (8.6% CAGR vs 7.6%).

Frost Bank is an American bank based in San Antonio that is chartered in Texas, with 200 branches and 1,750 automated teller machines in the state. It is the primary subsidiary of Cullen/Frost Bankers, Inc., a bank holding company. It is one of the 60 largest banks of the country by total assets.

Integra LifeSciences Holdings Corporation is a global medical device manufacturing company headquartered in Princeton, New Jersey. Founded in 1989, the company manufactures products for skin regeneration, neurosurgery, reconstructive and general surgery. Integra artificial skin became the first commercially reproducible skin tissue used to treat severe burns and other skin wounds.

CFR vs IART — Head-to-Head

Bigger by revenue
CFR
CFR
1.3× larger
CFR
$580.9M
$434.9M
IART
Growing faster (revenue YoY)
CFR
CFR
+10.0% gap
CFR
8.3%
-1.7%
IART
More free cash flow
CFR
CFR
$132.7M more FCF
CFR
$127.3M
$-5.4M
IART
Faster 2-yr revenue CAGR
IART
IART
Annualised
IART
8.6%
7.6%
CFR

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CFR
CFR
IART
IART
Revenue
$580.9M
$434.9M
Net Profit
$166.3M
Gross Margin
50.8%
Operating Margin
34.1%
5.3%
Net Margin
28.6%
Revenue YoY
8.3%
-1.7%
Net Profit YoY
7.4%
EPS (diluted)
$2.56
$-0.03

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CFR
CFR
IART
IART
Q4 25
$580.9M
$434.9M
Q3 25
$567.3M
$402.1M
Q2 25
$546.9M
$415.6M
Q1 25
$540.2M
$382.7M
Q4 24
$536.3M
$442.6M
Q3 24
$518.0M
$380.8M
Q2 24
$507.9M
$418.2M
Q1 24
$501.4M
$368.9M
Net Profit
CFR
CFR
IART
IART
Q4 25
$166.3M
Q3 25
$174.4M
$-5.4M
Q2 25
$157.0M
$-484.1M
Q1 25
$150.9M
$-25.3M
Q4 24
$154.9M
Q3 24
$146.5M
$-10.7M
Q2 24
$145.5M
$-12.4M
Q1 24
$135.7M
$-3.3M
Gross Margin
CFR
CFR
IART
IART
Q4 25
50.8%
Q3 25
51.5%
Q2 25
50.4%
Q1 25
50.8%
Q4 24
56.3%
Q3 24
52.6%
Q2 24
54.0%
Q1 24
56.1%
Operating Margin
CFR
CFR
IART
IART
Q4 25
34.1%
5.3%
Q3 25
36.7%
2.9%
Q2 25
34.1%
-123.4%
Q1 25
33.2%
-4.0%
Q4 24
34.3%
8.0%
Q3 24
33.8%
-2.1%
Q2 24
34.5%
-0.7%
Q1 24
32.2%
1.1%
Net Margin
CFR
CFR
IART
IART
Q4 25
28.6%
Q3 25
30.7%
-1.3%
Q2 25
28.7%
-116.5%
Q1 25
27.9%
-6.6%
Q4 24
28.9%
Q3 24
28.3%
-2.8%
Q2 24
28.6%
-3.0%
Q1 24
27.1%
-0.9%
EPS (diluted)
CFR
CFR
IART
IART
Q4 25
$2.56
$-0.03
Q3 25
$2.67
$-0.07
Q2 25
$2.39
$-6.31
Q1 25
$2.30
$-0.33
Q4 24
$2.36
$0.25
Q3 24
$2.24
$-0.14
Q2 24
$2.21
$-0.16
Q1 24
$2.06
$-0.04

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CFR
CFR
IART
IART
Cash + ST InvestmentsLiquidity on hand
$263.7M
Total DebtLower is stronger
$726.6M
Stockholders' EquityBook value
$4.6B
$1.0B
Total Assets
$53.0B
$3.6B
Debt / EquityLower = less leverage
0.70×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CFR
CFR
IART
IART
Q4 25
$263.7M
Q3 25
$267.9M
Q2 25
$253.6M
Q1 25
$273.3M
Q4 24
$273.6M
Q3 24
$277.6M
Q2 24
$296.9M
Q1 24
$663.1M
Total Debt
CFR
CFR
IART
IART
Q4 25
$726.6M
Q3 25
$736.3M
Q2 25
$745.9M
Q1 25
$755.6M
Q4 24
$760.5M
Q3 24
$765.3M
Q2 24
$770.2M
Q1 24
$775.0M
Stockholders' Equity
CFR
CFR
IART
IART
Q4 25
$4.6B
$1.0B
Q3 25
$4.5B
$1.0B
Q2 25
$4.2B
$1.0B
Q1 25
$4.1B
$1.5B
Q4 24
$3.9B
$1.5B
Q3 24
$4.1B
$1.5B
Q2 24
$3.7B
$1.5B
Q1 24
$3.6B
$1.6B
Total Assets
CFR
CFR
IART
IART
Q4 25
$53.0B
$3.6B
Q3 25
$52.5B
$3.6B
Q2 25
$51.4B
$3.7B
Q1 25
$52.0B
$4.1B
Q4 24
$52.5B
$4.0B
Q3 24
$51.0B
$4.1B
Q2 24
$48.8B
$4.1B
Q1 24
$49.5B
$4.1B
Debt / Equity
CFR
CFR
IART
IART
Q4 25
0.70×
Q3 25
0.71×
Q2 25
0.72×
Q1 25
0.50×
Q4 24
0.49×
Q3 24
0.50×
Q2 24
0.50×
Q1 24
0.48×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CFR
CFR
IART
IART
Operating Cash FlowLast quarter
$274.0M
$11.8M
Free Cash FlowOCF − Capex
$127.3M
$-5.4M
FCF MarginFCF / Revenue
21.9%
-1.2%
Capex IntensityCapex / Revenue
25.2%
4.0%
Cash ConversionOCF / Net Profit
1.65×
TTM Free Cash FlowTrailing 4 quarters
$116.4M
$-31.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CFR
CFR
IART
IART
Q4 25
$274.0M
$11.8M
Q3 25
$248.6M
$40.9M
Q2 25
$140.8M
$8.9M
Q1 25
$-296.1M
$-11.3M
Q4 24
$989.5M
$50.7M
Q3 24
$307.2M
$22.5M
Q2 24
$129.6M
$40.4M
Q1 24
$488.4M
$15.8M
Free Cash Flow
CFR
CFR
IART
IART
Q4 25
$127.3M
$-5.4M
Q3 25
$211.7M
$25.8M
Q2 25
$114.5M
$-11.2M
Q1 25
$-337.1M
$-40.2M
Q4 24
$861.8M
$21.1M
Q3 24
$281.9M
$-7.2M
Q2 24
$103.0M
$10.7M
Q1 24
$450.3M
$291.0K
FCF Margin
CFR
CFR
IART
IART
Q4 25
21.9%
-1.2%
Q3 25
37.3%
6.4%
Q2 25
20.9%
-2.7%
Q1 25
-62.4%
-10.5%
Q4 24
160.7%
4.8%
Q3 24
54.4%
-1.9%
Q2 24
20.3%
2.6%
Q1 24
89.8%
0.1%
Capex Intensity
CFR
CFR
IART
IART
Q4 25
25.2%
4.0%
Q3 25
6.5%
3.8%
Q2 25
4.8%
4.8%
Q1 25
7.6%
7.6%
Q4 24
23.8%
6.7%
Q3 24
4.9%
7.8%
Q2 24
5.2%
7.1%
Q1 24
7.6%
4.2%
Cash Conversion
CFR
CFR
IART
IART
Q4 25
1.65×
Q3 25
1.43×
Q2 25
0.90×
Q1 25
-1.96×
Q4 24
6.39×
Q3 24
2.10×
Q2 24
0.89×
Q1 24
3.60×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CFR
CFR

Segment breakdown not available.

IART
IART

Neurosurgery$226.2M52%
Asia Pacific$53.7M12%
Instruments$52.3M12%
ENT$44.8M10%
Other$38.9M9%
Rest Of The World$19.0M4%

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