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Side-by-side financial comparison of CULLEN/FROST BANKERS, INC. (CFR) and Lantheus Holdings, Inc. (LNTH). Click either name above to swap in a different company.

CULLEN/FROST BANKERS, INC. is the larger business by last-quarter revenue ($580.9M vs $406.8M, roughly 1.4× Lantheus Holdings, Inc.). CULLEN/FROST BANKERS, INC. runs the higher net margin — 28.6% vs 13.3%, a 15.3% gap on every dollar of revenue. On growth, CULLEN/FROST BANKERS, INC. posted the faster year-over-year revenue change (8.3% vs 4.0%). CULLEN/FROST BANKERS, INC. produced more free cash flow last quarter ($127.3M vs $81.4M). Over the past eight quarters, CULLEN/FROST BANKERS, INC.'s revenue compounded faster (7.6% CAGR vs 4.9%).

Frost Bank is an American bank based in San Antonio that is chartered in Texas, with 200 branches and 1,750 automated teller machines in the state. It is the primary subsidiary of Cullen/Frost Bankers, Inc., a bank holding company. It is one of the 60 largest banks of the country by total assets.

Lantheus Holdings, Inc. is a global healthcare firm specializing in the development, manufacturing and commercialization of innovative diagnostic imaging agents and related solutions. Its offerings cover core medical segments including oncology, cardiology and urology, with primary markets across North America and other key global regions.

CFR vs LNTH — Head-to-Head

Bigger by revenue
CFR
CFR
1.4× larger
CFR
$580.9M
$406.8M
LNTH
Growing faster (revenue YoY)
CFR
CFR
+4.3% gap
CFR
8.3%
4.0%
LNTH
Higher net margin
CFR
CFR
15.3% more per $
CFR
28.6%
13.3%
LNTH
More free cash flow
CFR
CFR
$45.9M more FCF
CFR
$127.3M
$81.4M
LNTH
Faster 2-yr revenue CAGR
CFR
CFR
Annualised
CFR
7.6%
4.9%
LNTH

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CFR
CFR
LNTH
LNTH
Revenue
$580.9M
$406.8M
Net Profit
$166.3M
$54.1M
Gross Margin
59.2%
Operating Margin
34.1%
19.0%
Net Margin
28.6%
13.3%
Revenue YoY
8.3%
4.0%
Net Profit YoY
7.4%
558.8%
EPS (diluted)
$2.56
$0.86

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CFR
CFR
LNTH
LNTH
Q4 25
$580.9M
$406.8M
Q3 25
$567.3M
$384.0M
Q2 25
$546.9M
$378.0M
Q1 25
$540.2M
$372.8M
Q4 24
$536.3M
$391.1M
Q3 24
$518.0M
$378.7M
Q2 24
$507.9M
$394.1M
Q1 24
$501.4M
$370.0M
Net Profit
CFR
CFR
LNTH
LNTH
Q4 25
$166.3M
$54.1M
Q3 25
$174.4M
$27.8M
Q2 25
$157.0M
$78.8M
Q1 25
$150.9M
$72.9M
Q4 24
$154.9M
$-11.8M
Q3 24
$146.5M
$131.1M
Q2 24
$145.5M
$62.1M
Q1 24
$135.7M
$131.1M
Gross Margin
CFR
CFR
LNTH
LNTH
Q4 25
59.2%
Q3 25
57.9%
Q2 25
63.8%
Q1 25
63.8%
Q4 24
63.5%
Q3 24
63.9%
Q2 24
64.9%
Q1 24
65.4%
Operating Margin
CFR
CFR
LNTH
LNTH
Q4 25
34.1%
19.0%
Q3 25
36.7%
11.4%
Q2 25
34.1%
23.3%
Q1 25
33.2%
27.4%
Q4 24
34.3%
29.1%
Q3 24
33.8%
35.3%
Q2 24
34.5%
26.1%
Q1 24
32.2%
28.8%
Net Margin
CFR
CFR
LNTH
LNTH
Q4 25
28.6%
13.3%
Q3 25
30.7%
7.2%
Q2 25
28.7%
20.8%
Q1 25
27.9%
19.6%
Q4 24
28.9%
-3.0%
Q3 24
28.3%
34.6%
Q2 24
28.6%
15.8%
Q1 24
27.1%
35.4%
EPS (diluted)
CFR
CFR
LNTH
LNTH
Q4 25
$2.56
$0.86
Q3 25
$2.67
$0.41
Q2 25
$2.39
$1.12
Q1 25
$2.30
$1.02
Q4 24
$2.36
$-0.18
Q3 24
$2.24
$1.79
Q2 24
$2.21
$0.88
Q1 24
$2.06
$1.87

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CFR
CFR
LNTH
LNTH
Cash + ST InvestmentsLiquidity on hand
$359.1M
Total DebtLower is stronger
$568.7M
Stockholders' EquityBook value
$4.6B
$1.1B
Total Assets
$53.0B
$2.2B
Debt / EquityLower = less leverage
0.52×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CFR
CFR
LNTH
LNTH
Q4 25
$359.1M
Q3 25
$382.0M
Q2 25
$695.6M
Q1 25
$938.5M
Q4 24
$912.8M
Q3 24
$866.4M
Q2 24
$757.0M
Q1 24
$718.3M
Total Debt
CFR
CFR
LNTH
LNTH
Q4 25
$568.7M
Q3 25
$567.9M
Q2 25
$566.8M
Q1 25
$566.1M
Q4 24
$565.3M
Q3 24
$613.0K
Q2 24
$563.2M
Q1 24
$562.5M
Stockholders' Equity
CFR
CFR
LNTH
LNTH
Q4 25
$4.6B
$1.1B
Q3 25
$4.5B
$1.1B
Q2 25
$4.2B
$1.2B
Q1 25
$4.1B
$1.2B
Q4 24
$3.9B
$1.1B
Q3 24
$4.1B
$1.2B
Q2 24
$3.7B
$1.0B
Q1 24
$3.6B
$945.5M
Total Assets
CFR
CFR
LNTH
LNTH
Q4 25
$53.0B
$2.2B
Q3 25
$52.5B
$2.3B
Q2 25
$51.4B
$2.1B
Q1 25
$52.0B
$2.1B
Q4 24
$52.5B
$2.0B
Q3 24
$51.0B
$2.0B
Q2 24
$48.8B
$1.9B
Q1 24
$49.5B
$1.8B
Debt / Equity
CFR
CFR
LNTH
LNTH
Q4 25
0.52×
Q3 25
0.51×
Q2 25
0.49×
Q1 25
0.49×
Q4 24
0.52×
Q3 24
0.00×
Q2 24
0.55×
Q1 24
0.59×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CFR
CFR
LNTH
LNTH
Operating Cash FlowLast quarter
$274.0M
$90.2M
Free Cash FlowOCF − Capex
$127.3M
$81.4M
FCF MarginFCF / Revenue
21.9%
20.0%
Capex IntensityCapex / Revenue
25.2%
2.2%
Cash ConversionOCF / Net Profit
1.65×
1.67×
TTM Free Cash FlowTrailing 4 quarters
$116.4M
$354.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CFR
CFR
LNTH
LNTH
Q4 25
$274.0M
$90.2M
Q3 25
$248.6M
$105.3M
Q2 25
$140.8M
$87.1M
Q1 25
$-296.1M
$107.6M
Q4 24
$989.5M
$157.7M
Q3 24
$307.2M
$175.1M
Q2 24
$129.6M
$84.7M
Q1 24
$488.4M
$127.2M
Free Cash Flow
CFR
CFR
LNTH
LNTH
Q4 25
$127.3M
$81.4M
Q3 25
$211.7M
$94.7M
Q2 25
$114.5M
$79.1M
Q1 25
$-337.1M
$98.8M
Q4 24
$861.8M
$141.4M
Q3 24
$281.9M
$159.3M
Q2 24
$103.0M
$73.5M
Q1 24
$450.3M
$119.0M
FCF Margin
CFR
CFR
LNTH
LNTH
Q4 25
21.9%
20.0%
Q3 25
37.3%
24.7%
Q2 25
20.9%
20.9%
Q1 25
-62.4%
26.5%
Q4 24
160.7%
36.1%
Q3 24
54.4%
42.0%
Q2 24
20.3%
18.7%
Q1 24
89.8%
32.2%
Capex Intensity
CFR
CFR
LNTH
LNTH
Q4 25
25.2%
2.2%
Q3 25
6.5%
2.8%
Q2 25
4.8%
2.1%
Q1 25
7.6%
2.3%
Q4 24
23.8%
4.2%
Q3 24
4.9%
4.2%
Q2 24
5.2%
2.8%
Q1 24
7.6%
2.2%
Cash Conversion
CFR
CFR
LNTH
LNTH
Q4 25
1.65×
1.67×
Q3 25
1.43×
3.79×
Q2 25
0.90×
1.11×
Q1 25
-1.96×
1.47×
Q4 24
6.39×
Q3 24
2.10×
1.34×
Q2 24
0.89×
1.36×
Q1 24
3.60×
0.97×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CFR
CFR

Segment breakdown not available.

LNTH
LNTH

Radiopharmaceutical Oncology$240.2M59%
Definity$85.3M21%
Strategic Partnerships And Other$23.3M6%
Techne Lite$21.0M5%
Licenseand Royalty Revenues$17.4M4%
Other$13.6M3%
Other Precision Diagnostics$5.9M1%

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