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Side-by-side financial comparison of COMERICA INC (CMA) and Medpace Holdings, Inc. (MEDP). Click either name above to swap in a different company.
COMERICA INC is the larger business by last-quarter revenue ($838.0M vs $708.5M, roughly 1.2× Medpace Holdings, Inc.). COMERICA INC runs the higher net margin — 21.0% vs 19.1%, a 1.9% gap on every dollar of revenue. On growth, Medpace Holdings, Inc. posted the faster year-over-year revenue change (32.0% vs 3.3%). Over the past eight quarters, COMERICA INC's revenue compounded faster (108.9% CAGR vs 17.7%).
Comerica Incorporated is an American financial services company, headquartered in Dallas, Texas. It is the parent of Comerica Bank, a regional commercial bank with 413 branches in the U.S. states of Texas, Michigan, California, Florida and Arizona. Comerica is among the largest U.S. financial holding companies, with offices in a number of U.S. cities.
Medpace Holdings, Inc. is a global clinical research organization (CRO) based in Cincinnati, Ohio, employing approximately 6,000 people. Operating under a full-service model, the company also offers global central laboratory, imaging core laboratory, and bioanalytical laboratory services, as well as a Phase I unit located on its headquarters and clinical research campus in Cincinnati, Ohio.
CMA vs MEDP — Head-to-Head
Income Statement — Q3 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $838.0M | $708.5M |
| Net Profit | $176.0M | $135.1M |
| Gross Margin | — | — |
| Operating Margin | — | 21.6% |
| Net Margin | 21.0% | 19.1% |
| Revenue YoY | 3.3% | 32.0% |
| Net Profit YoY | -4.3% | 15.5% |
| EPS (diluted) | $1.35 | $4.65 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | — | $708.5M | ||
| Q3 25 | $838.0M | $659.9M | ||
| Q2 25 | $849.0M | $603.3M | ||
| Q1 25 | $829.0M | $558.6M | ||
| Q4 24 | $825.0M | $536.6M | ||
| Q3 24 | $811.0M | $533.3M | ||
| Q2 24 | $824.0M | $528.1M | ||
| Q1 24 | $784.0M | $511.0M |
| Q4 25 | — | $135.1M | ||
| Q3 25 | $176.0M | $111.1M | ||
| Q2 25 | $199.0M | $90.3M | ||
| Q1 25 | $172.0M | $114.6M | ||
| Q4 24 | $170.0M | $117.0M | ||
| Q3 24 | $184.0M | $96.4M | ||
| Q2 24 | $206.0M | $88.4M | ||
| Q1 24 | $138.0M | $102.6M |
| Q4 25 | — | 21.6% | ||
| Q3 25 | — | 21.5% | ||
| Q2 25 | — | 20.9% | ||
| Q1 25 | — | 20.3% | ||
| Q4 24 | — | 23.4% | ||
| Q3 24 | — | 21.1% | ||
| Q2 24 | — | 19.9% | ||
| Q1 24 | — | 20.4% |
| Q4 25 | — | 19.1% | ||
| Q3 25 | 21.0% | 16.8% | ||
| Q2 25 | 23.4% | 15.0% | ||
| Q1 25 | 20.7% | 20.5% | ||
| Q4 24 | 20.6% | 21.8% | ||
| Q3 24 | 22.7% | 18.1% | ||
| Q2 24 | 25.0% | 16.7% | ||
| Q1 24 | 17.6% | 20.1% |
| Q4 25 | — | $4.65 | ||
| Q3 25 | $1.35 | $3.86 | ||
| Q2 25 | $1.42 | $3.10 | ||
| Q1 25 | $1.25 | $3.67 | ||
| Q4 24 | $1.22 | $3.67 | ||
| Q3 24 | $1.33 | $3.01 | ||
| Q2 24 | $1.49 | $2.75 | ||
| Q1 24 | $0.98 | $3.20 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | — | $497.0M |
| Total DebtLower is stronger | $5.4B | — |
| Stockholders' EquityBook value | $7.4B | $459.1M |
| Total Assets | $77.4B | $2.0B |
| Debt / EquityLower = less leverage | 0.73× | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $497.0M | ||
| Q3 25 | — | $285.4M | ||
| Q2 25 | — | $46.3M | ||
| Q1 25 | — | $441.4M | ||
| Q4 24 | — | $669.4M | ||
| Q3 24 | — | $656.9M | ||
| Q2 24 | — | $510.9M | ||
| Q1 24 | — | $407.0M |
| Q4 25 | — | — | ||
| Q3 25 | $5.4B | — | ||
| Q2 25 | $5.8B | — | ||
| Q1 25 | $5.7B | — | ||
| Q4 24 | $6.7B | — | ||
| Q3 24 | $6.8B | — | ||
| Q2 24 | $7.1B | — | ||
| Q1 24 | $7.1B | — |
| Q4 25 | — | $459.1M | ||
| Q3 25 | $7.4B | $293.6M | ||
| Q2 25 | $6.9B | $172.4M | ||
| Q1 25 | $7.1B | $593.6M | ||
| Q4 24 | $6.5B | $825.5M | ||
| Q3 24 | $7.4B | $881.4M | ||
| Q2 24 | $6.2B | $763.6M | ||
| Q1 24 | $6.0B | $671.5M |
| Q4 25 | — | $2.0B | ||
| Q3 25 | $77.4B | $1.8B | ||
| Q2 25 | $78.0B | $1.6B | ||
| Q1 25 | $77.6B | $1.9B | ||
| Q4 24 | $79.3B | $2.1B | ||
| Q3 24 | $79.7B | $2.1B | ||
| Q2 24 | $79.6B | $1.9B | ||
| Q1 24 | $79.4B | $1.8B |
| Q4 25 | — | — | ||
| Q3 25 | 0.73× | — | ||
| Q2 25 | 0.84× | — | ||
| Q1 25 | 0.81× | — | ||
| Q4 24 | 1.02× | — | ||
| Q3 24 | 0.92× | — | ||
| Q2 24 | 1.15× | — | ||
| Q1 24 | 1.18× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-270.0M | $192.7M |
| Free Cash FlowOCF − Capex | — | $188.1M |
| FCF MarginFCF / Revenue | — | 26.6% |
| Capex IntensityCapex / Revenue | — | 0.6% |
| Cash ConversionOCF / Net Profit | -1.53× | 1.43× |
| TTM Free Cash FlowTrailing 4 quarters | — | $681.9M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $192.7M | ||
| Q3 25 | $-270.0M | $246.2M | ||
| Q2 25 | $476.0M | $148.5M | ||
| Q1 25 | $273.0M | $125.8M | ||
| Q4 24 | $601.0M | $190.7M | ||
| Q3 24 | $1.0B | $149.1M | ||
| Q2 24 | $111.0M | $116.4M | ||
| Q1 24 | $-205.0M | $152.7M |
| Q4 25 | — | $188.1M | ||
| Q3 25 | — | $235.5M | ||
| Q2 25 | — | $142.4M | ||
| Q1 25 | — | $115.8M | ||
| Q4 24 | — | $183.0M | ||
| Q3 24 | — | $138.5M | ||
| Q2 24 | — | $103.5M | ||
| Q1 24 | — | $147.2M |
| Q4 25 | — | 26.6% | ||
| Q3 25 | — | 35.7% | ||
| Q2 25 | — | 23.6% | ||
| Q1 25 | — | 20.7% | ||
| Q4 24 | — | 34.1% | ||
| Q3 24 | — | 26.0% | ||
| Q2 24 | — | 19.6% | ||
| Q1 24 | — | 28.8% |
| Q4 25 | — | 0.6% | ||
| Q3 25 | — | 1.6% | ||
| Q2 25 | — | 1.0% | ||
| Q1 25 | — | 1.8% | ||
| Q4 24 | — | 1.4% | ||
| Q3 24 | — | 2.0% | ||
| Q2 24 | — | 2.4% | ||
| Q1 24 | — | 1.1% |
| Q4 25 | — | 1.43× | ||
| Q3 25 | -1.53× | 2.22× | ||
| Q2 25 | 2.39× | 1.65× | ||
| Q1 25 | 1.59× | 1.10× | ||
| Q4 24 | 3.54× | 1.63× | ||
| Q3 24 | 5.70× | 1.55× | ||
| Q2 24 | 0.54× | 1.32× | ||
| Q1 24 | -1.49× | 1.49× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
CMA
Segment breakdown not available.
MEDP
| Metabolic | $249.8M | 35% |
| Oncology | $195.9M | 28% |
| Other | $88.3M | 12% |
| Central Nervous System | $73.2M | 10% |
| Cardiology | $63.0M | 9% |
| Antiviral And Anti Infective | $38.3M | 5% |
| Related Party | $10.3M | 1% |
