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Side-by-side financial comparison of Cannae Holdings, Inc. (CNNE) and CASTLE BIOSCIENCES INC (CSTL). Click either name above to swap in a different company.

Cannae Holdings, Inc. is the larger business by last-quarter revenue ($103.3M vs $87.0M, roughly 1.2× CASTLE BIOSCIENCES INC). On growth, CASTLE BIOSCIENCES INC posted the faster year-over-year revenue change (0.8% vs -6.0%). CASTLE BIOSCIENCES INC produced more free cash flow last quarter ($19.7M vs $12.0M). Over the past eight quarters, CASTLE BIOSCIENCES INC's revenue compounded faster (9.2% CAGR vs -3.4%).

Cannae Holdings, Inc. is a diversified holding company that primarily invests in and operates businesses across multiple sectors including financial services, restaurant and hospitality, technology, and healthcare. Its core market is the United States, and it focuses on driving long-term stakeholder value through active portfolio management and strategic operational support for its portfolio companies.

Castle Biosciences Inc. is a commercial-stage diagnostic firm that develops and markets proprietary, clinically actionable tests for dermatological conditions such as melanoma and other skin cancers, plus rare diseases. It operates mainly in the U.S. healthcare market, focusing on segments with high unmet need for more accurate diagnostics to guide treatment choices.

CNNE vs CSTL — Head-to-Head

Bigger by revenue
CNNE
CNNE
1.2× larger
CNNE
$103.3M
$87.0M
CSTL
Growing faster (revenue YoY)
CSTL
CSTL
+6.8% gap
CSTL
0.8%
-6.0%
CNNE
More free cash flow
CSTL
CSTL
$7.7M more FCF
CSTL
$19.7M
$12.0M
CNNE
Faster 2-yr revenue CAGR
CSTL
CSTL
Annualised
CSTL
9.2%
-3.4%
CNNE

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CNNE
CNNE
CSTL
CSTL
Revenue
$103.3M
$87.0M
Net Profit
$-93.0M
Gross Margin
15.2%
79.0%
Operating Margin
-23.3%
-4.4%
Net Margin
-90.0%
Revenue YoY
-6.0%
0.8%
Net Profit YoY
-101.7%
EPS (diluted)
$-2.09
$-0.06

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CNNE
CNNE
CSTL
CSTL
Q4 25
$103.3M
$87.0M
Q3 25
$106.9M
$83.0M
Q2 25
$110.2M
$86.2M
Q1 25
$103.2M
$88.0M
Q4 24
$109.9M
$86.3M
Q3 24
$113.9M
$85.8M
Q2 24
$118.0M
$87.0M
Q1 24
$110.7M
$73.0M
Net Profit
CNNE
CNNE
CSTL
CSTL
Q4 25
$-93.0M
Q3 25
$-68.4M
$-501.0K
Q2 25
$-238.8M
$4.5M
Q1 25
$-113.0M
$-25.8M
Q4 24
$-46.1M
Q3 24
$-13.6M
$2.3M
Q2 24
$-155.0M
$8.9M
Q1 24
$-89.9M
$-2.5M
Gross Margin
CNNE
CNNE
CSTL
CSTL
Q4 25
15.2%
79.0%
Q3 25
17.1%
77.5%
Q2 25
17.6%
79.5%
Q1 25
11.8%
81.4%
Q4 24
16.4%
81.3%
Q3 24
18.3%
81.8%
Q2 24
21.9%
83.3%
Q1 24
14.9%
81.0%
Operating Margin
CNNE
CNNE
CSTL
CSTL
Q4 25
-23.3%
-4.4%
Q3 25
-12.3%
-8.2%
Q2 25
-55.3%
-4.9%
Q1 25
-20.7%
-31.7%
Q4 24
-20.0%
4.7%
Q3 24
-15.9%
5.9%
Q2 24
-19.5%
5.8%
Q1 24
-36.7%
-7.5%
Net Margin
CNNE
CNNE
CSTL
CSTL
Q4 25
-90.0%
Q3 25
-64.0%
-0.6%
Q2 25
-216.7%
5.2%
Q1 25
-109.5%
-29.4%
Q4 24
-41.9%
Q3 24
-11.9%
2.6%
Q2 24
-131.4%
10.3%
Q1 24
-81.2%
-3.5%
EPS (diluted)
CNNE
CNNE
CSTL
CSTL
Q4 25
$-2.09
$-0.06
Q3 25
$-1.25
$-0.02
Q2 25
$-3.93
$0.15
Q1 25
$-1.81
$-0.90
Q4 24
$-0.75
$0.32
Q3 24
$-0.22
$0.08
Q2 24
$-2.49
$0.31
Q1 24
$-1.27
$-0.09

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CNNE
CNNE
CSTL
CSTL
Cash + ST InvestmentsLiquidity on hand
$182.0M
$299.5M
Total DebtLower is stronger
$70.8M
$10.1M
Stockholders' EquityBook value
$1.0B
$470.9M
Total Assets
$1.3B
$578.6M
Debt / EquityLower = less leverage
0.07×
0.02×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CNNE
CNNE
CSTL
CSTL
Q4 25
$182.0M
$299.5M
Q3 25
$233.8M
$287.5M
Q2 25
$66.7M
$275.9M
Q1 25
$126.2M
$275.2M
Q4 24
$131.5M
$293.1M
Q3 24
$95.0M
Q2 24
$85.6M
Q1 24
$82.9M
Total Debt
CNNE
CNNE
CSTL
CSTL
Q4 25
$70.8M
$10.1M
Q3 25
$68.6M
$10.0M
Q2 25
$168.4M
$10.0M
Q1 25
$170.6M
$10.0M
Q4 24
$181.0M
$10.0M
Q3 24
$181.2M
$10.0M
Q2 24
$78.2M
$10.0M
Q1 24
$79.3M
$10.0M
Stockholders' Equity
CNNE
CNNE
CSTL
CSTL
Q4 25
$1.0B
$470.9M
Q3 25
$1.2B
$467.0M
Q2 25
$1.4B
$455.4M
Q1 25
$1.7B
$440.3M
Q4 24
$1.8B
$455.8M
Q3 24
$1.9B
$441.1M
Q2 24
$1.9B
$423.9M
Q1 24
$2.3B
$402.5M
Total Assets
CNNE
CNNE
CSTL
CSTL
Q4 25
$1.3B
$578.6M
Q3 25
$1.5B
$562.8M
Q2 25
$1.8B
$544.7M
Q1 25
$2.1B
$501.7M
Q4 24
$2.2B
$531.2M
Q3 24
$2.3B
$514.6M
Q2 24
$2.2B
$487.3M
Q1 24
$2.6B
$458.5M
Debt / Equity
CNNE
CNNE
CSTL
CSTL
Q4 25
0.07×
0.02×
Q3 25
0.06×
0.02×
Q2 25
0.12×
0.02×
Q1 25
0.10×
0.02×
Q4 24
0.10×
0.02×
Q3 24
0.10×
0.02×
Q2 24
0.04×
0.02×
Q1 24
0.03×
0.02×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CNNE
CNNE
CSTL
CSTL
Operating Cash FlowLast quarter
$16.0M
$26.9M
Free Cash FlowOCF − Capex
$12.0M
$19.7M
FCF MarginFCF / Revenue
11.6%
22.7%
Capex IntensityCapex / Revenue
3.9%
8.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-28.5M
$28.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CNNE
CNNE
CSTL
CSTL
Q4 25
$16.0M
$26.9M
Q3 25
$-21.6M
$22.6M
Q2 25
$-21.6M
$20.8M
Q1 25
$9.1M
$-6.0M
Q4 24
$-12.0M
$24.4M
Q3 24
$-31.9M
$23.3M
Q2 24
$-10.2M
$24.0M
Q1 24
$-36.0M
$-6.8M
Free Cash Flow
CNNE
CNNE
CSTL
CSTL
Q4 25
$12.0M
$19.7M
Q3 25
$-24.1M
$7.8M
Q2 25
$-23.6M
$11.6M
Q1 25
$7.2M
$-10.8M
Q4 24
$-14.4M
$16.8M
Q3 24
$-33.6M
$17.0M
Q2 24
$-11.8M
$18.8M
Q1 24
$-37.3M
$-16.0M
FCF Margin
CNNE
CNNE
CSTL
CSTL
Q4 25
11.6%
22.7%
Q3 25
-22.5%
9.4%
Q2 25
-21.4%
13.4%
Q1 25
7.0%
-12.2%
Q4 24
-13.1%
19.5%
Q3 24
-29.5%
19.8%
Q2 24
-10.0%
21.6%
Q1 24
-33.7%
-21.9%
Capex Intensity
CNNE
CNNE
CSTL
CSTL
Q4 25
3.9%
8.3%
Q3 25
2.3%
17.9%
Q2 25
1.8%
10.7%
Q1 25
1.8%
5.4%
Q4 24
2.2%
8.8%
Q3 24
1.5%
7.4%
Q2 24
1.4%
6.0%
Q1 24
1.2%
12.5%
Cash Conversion
CNNE
CNNE
CSTL
CSTL
Q4 25
Q3 25
Q2 25
4.60×
Q1 25
Q4 24
Q3 24
10.29×
Q2 24
2.69×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CNNE
CNNE

Reportable Segment Aggregation Before Other Operating Segment$94.9M92%
Other Operating Revenue$8.4M8%

CSTL
CSTL

Dermatologic$48.6M56%
Non Dermatologic$38.4M44%

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