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Side-by-side financial comparison of Connect Biopharma Holdings Ltd (CNTB) and Usio, Inc. (USIO). Click either name above to swap in a different company.

Connect Biopharma Holdings Ltd is the larger business by last-quarter revenue ($24.1M vs $22.2M, roughly 1.1× Usio, Inc.). Connect Biopharma Holdings Ltd runs the higher net margin — 61.6% vs -6.7%, a 68.3% gap on every dollar of revenue.

Connect Biopharma Holdings Ltd is a clinical-stage global biopharmaceutical company dedicated to developing innovative targeted therapies for inflammatory, immunological and autoimmune diseases. Its core pipeline includes candidate treatments for asthma, atopic dermatitis and other conditions with high unmet medical needs, with main operations across the U.S., China and key global markets to deliver effective therapeutic solutions to patients.

Usio, Inc. is an American financial technology company headquartered in San Antonio, Texas. It provides integrated electronic payment services, including ACH processing, credit card and debit card acceptance, payment facilitation for software platforms, prepaid card issuing and a document print and mail operation.

CNTB vs USIO — Head-to-Head

Bigger by revenue
CNTB
CNTB
1.1× larger
CNTB
$24.1M
$22.2M
USIO
Higher net margin
CNTB
CNTB
68.3% more per $
CNTB
61.6%
-6.7%
USIO

Income Statement — Q2 FY2024 vs Q4 FY2025

Metric
CNTB
CNTB
USIO
USIO
Revenue
$24.1M
$22.2M
Net Profit
$14.8M
$-1.5M
Gross Margin
21.9%
Operating Margin
56.6%
-5.7%
Net Margin
61.6%
-6.7%
Revenue YoY
8.2%
Net Profit YoY
148.7%
-337.8%
EPS (diluted)
$0.27
$-0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CNTB
CNTB
USIO
USIO
Q4 25
$22.2M
Q3 25
$21.2M
Q2 25
$20.0M
Q1 25
$22.0M
Q4 24
$20.6M
Q3 24
$21.3M
Q2 24
$24.1M
$20.1M
Q1 24
$21.0M
Net Profit
CNTB
CNTB
USIO
USIO
Q4 25
$-1.5M
Q3 25
$-415.1K
Q2 25
$-366.7K
Q1 25
$-235.0K
Q4 24
$628.9K
Q3 24
$2.9M
Q2 24
$14.8M
$75.5K
Q1 24
$-250.2K
Gross Margin
CNTB
CNTB
USIO
USIO
Q4 25
21.9%
Q3 25
23.0%
Q2 25
25.8%
Q1 25
21.9%
Q4 24
24.6%
Q3 24
23.0%
Q2 24
23.9%
Q1 24
23.1%
Operating Margin
CNTB
CNTB
USIO
USIO
Q4 25
-5.7%
Q3 25
-2.2%
Q2 25
-2.0%
Q1 25
-1.1%
Q4 24
-2.9%
Q3 24
-1.8%
Q2 24
56.6%
-1.0%
Q1 24
-1.3%
Net Margin
CNTB
CNTB
USIO
USIO
Q4 25
-6.7%
Q3 25
-2.0%
Q2 25
-1.8%
Q1 25
-1.1%
Q4 24
3.1%
Q3 24
13.4%
Q2 24
61.6%
0.4%
Q1 24
-1.2%
EPS (diluted)
CNTB
CNTB
USIO
USIO
Q4 25
$-0.05
Q3 25
$-0.02
Q2 25
$-0.01
Q1 25
$-0.01
Q4 24
$0.03
Q3 24
$0.10
Q2 24
$0.27
$0.00
Q1 24
$-0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CNTB
CNTB
USIO
USIO
Cash + ST InvestmentsLiquidity on hand
$110.2M
$7.4M
Total DebtLower is stronger
$1.4M
Stockholders' EquityBook value
$110.9M
$17.9M
Total Assets
$120.6M
$134.9M
Debt / EquityLower = less leverage
0.08×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CNTB
CNTB
USIO
USIO
Q4 25
$7.4M
Q3 25
$7.7M
Q2 25
$8.1M
Q1 25
$8.7M
Q4 24
$8.1M
Q3 24
$8.4M
Q2 24
$110.2M
$7.2M
Q1 24
$7.1M
Total Debt
CNTB
CNTB
USIO
USIO
Q4 25
$1.4M
Q3 25
$836.7K
Q2 25
$647.1K
Q1 25
$683.3K
Q4 24
$719.4K
Q3 24
$562.9K
Q2 24
$597.2K
Q1 24
$630.9K
Stockholders' Equity
CNTB
CNTB
USIO
USIO
Q4 25
$17.9M
Q3 25
$18.7M
Q2 25
$18.7M
Q1 25
$19.0M
Q4 24
$19.2M
Q3 24
$18.9M
Q2 24
$110.9M
$15.7M
Q1 24
$15.3M
Total Assets
CNTB
CNTB
USIO
USIO
Q4 25
$134.9M
Q3 25
$99.4M
Q2 25
$108.4M
Q1 25
$109.6M
Q4 24
$107.2M
Q3 24
$114.6M
Q2 24
$120.6M
$108.8M
Q1 24
$99.1M
Debt / Equity
CNTB
CNTB
USIO
USIO
Q4 25
0.08×
Q3 25
0.04×
Q2 25
0.03×
Q1 25
0.04×
Q4 24
0.04×
Q3 24
0.03×
Q2 24
0.04×
Q1 24
0.04×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CNTB
CNTB
USIO
USIO
Operating Cash FlowLast quarter
$-8.0M
$1.5M
Free Cash FlowOCF − Capex
$1.1M
FCF MarginFCF / Revenue
4.8%
Capex IntensityCapex / Revenue
2.0%
Cash ConversionOCF / Net Profit
-0.54×
TTM Free Cash FlowTrailing 4 quarters
$1.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CNTB
CNTB
USIO
USIO
Q4 25
$1.5M
Q3 25
$303.8K
Q2 25
$-263.9K
Q1 25
$1.4M
Q4 24
$2.9M
Q3 24
$1.4M
Q2 24
$-8.0M
$369.1K
Q1 24
$88.7K
Free Cash Flow
CNTB
CNTB
USIO
USIO
Q4 25
$1.1M
Q3 25
$85.2K
Q2 25
$-503.2K
Q1 25
$1.1M
Q4 24
$2.7M
Q3 24
$1.4M
Q2 24
$246.3K
Q1 24
$-88.1K
FCF Margin
CNTB
CNTB
USIO
USIO
Q4 25
4.8%
Q3 25
0.4%
Q2 25
-2.5%
Q1 25
4.8%
Q4 24
13.1%
Q3 24
6.4%
Q2 24
1.2%
Q1 24
-0.4%
Capex Intensity
CNTB
CNTB
USIO
USIO
Q4 25
2.0%
Q3 25
1.0%
Q2 25
1.2%
Q1 25
1.4%
Q4 24
1.0%
Q3 24
0.3%
Q2 24
0.6%
Q1 24
0.8%
Cash Conversion
CNTB
CNTB
USIO
USIO
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
4.61×
Q3 24
0.50×
Q2 24
-0.54×
4.89×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CNTB
CNTB

Segment breakdown not available.

USIO
USIO

Credit Card Revenue$7.7M35%
ACH And Complementary Service Revenue$6.1M28%
Output Solutions$5.4M24%
Prepaid Card Services Revenue$2.6M12%

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