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Side-by-side financial comparison of Coya Therapeutics, Inc. (COYA) and Onfolio Holdings, Inc (ONFO). Click either name above to swap in a different company.

Coya Therapeutics, Inc. is the larger business by last-quarter revenue ($4.0M vs $2.0M, roughly 2.0× Onfolio Holdings, Inc). On growth, Coya Therapeutics, Inc. posted the faster year-over-year revenue change (202768.8% vs -20.1%).

Coya Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing innovative regulatory T cell (Treg)-based therapies to address unmet medical needs for patients with neurodegenerative, autoimmune, and inflammatory diseases. Its core pipeline includes lead candidates targeting conditions like amyotrophic lateral sclerosis, with primary planned commercial markets across North America and the European Union.

Onfolio Holdings Inc. acquires, manages and grows a diversified portfolio of small to medium-sized online businesses, including niche content sites, e-commerce stores, and SaaS tools. It operates primarily in North America and Western Europe, focusing on high-margin, sustainable digital assets with stable revenue streams.

COYA vs ONFO — Head-to-Head

Bigger by revenue
COYA
COYA
2.0× larger
COYA
$4.0M
$2.0M
ONFO
Growing faster (revenue YoY)
COYA
COYA
+202788.9% gap
COYA
202768.8%
-20.1%
ONFO

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
COYA
COYA
ONFO
ONFO
Revenue
$4.0M
$2.0M
Net Profit
$-547.1K
Gross Margin
50.0%
Operating Margin
-59.1%
Net Margin
-27.0%
Revenue YoY
202768.8%
-20.1%
Net Profit YoY
-95.8%
-69.0%
EPS (diluted)
$-0.37

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
COYA
COYA
ONFO
ONFO
Q4 25
$4.0M
$2.0M
Q3 25
$3.6M
$2.7M
Q2 25
$3.1M
Q1 25
$2.8M
Q4 24
$2.5M
Q3 24
$0
$2.0M
Q2 24
$3.4M
$1.7M
Q1 24
$1.6M
Net Profit
COYA
COYA
ONFO
ONFO
Q4 25
$-547.1K
Q3 25
$-2.1M
$-700.7K
Q2 25
$-534.4K
Q1 25
$-806.4K
Q4 24
$-323.8K
Q3 24
$-4.0M
$-335.6K
Q2 24
$-2.9M
$-629.0K
Q1 24
$-477.8K
Gross Margin
COYA
COYA
ONFO
ONFO
Q4 25
50.0%
Q3 25
64.6%
Q2 25
61.6%
Q1 25
60.7%
Q4 24
53.6%
Q3 24
59.9%
Q2 24
56.5%
Q1 24
63.3%
Operating Margin
COYA
COYA
ONFO
ONFO
Q4 25
-59.1%
Q3 25
-68.3%
-9.8%
Q2 25
-16.1%
Q1 25
-27.9%
Q4 24
-43.9%
Q3 24
-16.5%
Q2 24
-94.5%
-35.1%
Q1 24
-28.7%
Net Margin
COYA
COYA
ONFO
ONFO
Q4 25
-27.0%
Q3 25
-59.4%
-25.6%
Q2 25
-17.0%
Q1 25
-28.7%
Q4 24
-12.8%
Q3 24
-16.7%
Q2 24
-84.4%
-36.4%
Q1 24
-30.1%
EPS (diluted)
COYA
COYA
ONFO
ONFO
Q4 25
$-0.37
Q3 25
$-0.13
$-0.16
Q2 25
$0.13
Q1 25
$-0.18
Q4 24
$-0.36
Q3 24
$-0.26
$-0.08
Q2 24
$-0.19
$0.14
Q1 24
$-0.11

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
COYA
COYA
ONFO
ONFO
Cash + ST InvestmentsLiquidity on hand
$46.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$43.0M
$2.5M
Total Assets
$50.0M
$11.4M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
COYA
COYA
ONFO
ONFO
Q4 25
$46.8M
Q3 25
$28.1M
Q2 25
Q1 25
Q4 24
Q3 24
$31.1M
Q2 24
$36.6M
Q1 24
$529.8K
Stockholders' Equity
COYA
COYA
ONFO
ONFO
Q4 25
$43.0M
$2.5M
Q3 25
$27.3M
$2.2M
Q2 25
$3.1M
Q1 25
$3.6M
Q4 24
$3.3M
Q3 24
$32.0M
$3.9M
Q2 24
$35.3M
$4.5M
Q1 24
$5.2M
Total Assets
COYA
COYA
ONFO
ONFO
Q4 25
$50.0M
$11.4M
Q3 25
$32.0M
$8.3M
Q2 25
$8.8M
Q1 25
$9.4M
Q4 24
$9.6M
Q3 24
$35.6M
$8.6M
Q2 24
$39.9M
$8.9M
Q1 24
$8.7M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
COYA
COYA
ONFO
ONFO
Operating Cash FlowLast quarter
$-10.7M
$-397.3K
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
COYA
COYA
ONFO
ONFO
Q4 25
$-10.7M
$-397.3K
Q3 25
$-1.1M
$34.2K
Q2 25
$-430.1K
Q1 25
$-145.0K
Q4 24
$-471.6K
Q3 24
$-5.5M
$67.0K
Q2 24
$-4.6M
$-332.7K
Q1 24
$-431.0K

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

COYA
COYA

Segment breakdown not available.

ONFO
ONFO

B Two B$1.6M81%
B Two C$243.0K12%
Other$138.6K7%

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