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Side-by-side financial comparison of CATALYST PHARMACEUTICALS, INC. (CPRX) and PROASSURANCE CORP (PRA). Click either name above to swap in a different company.

PROASSURANCE CORP is the larger business by last-quarter revenue ($269.6M vs $152.6M, roughly 1.8× CATALYST PHARMACEUTICALS, INC.). CATALYST PHARMACEUTICALS, INC. runs the higher net margin — 34.5% vs 12.4%, a 22.2% gap on every dollar of revenue. On growth, CATALYST PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (7.6% vs -7.1%). Over the past eight quarters, CATALYST PHARMACEUTICALS, INC.'s revenue compounded faster (24.5% CAGR vs -2.7%).

Catalyst Pharmaceuticals, Inc. is a biopharmaceutical company based in Coral Gables, Florida, United States. The company develops medicines for rare diseases, including the phosphate salt of amifampridine for the treatment of Lambert–Eaton myasthenic syndrome (LEMS). The drug is referred to under the trade name Firdapse, which was approved by the FDA for approved use in children 6 years and older with LEMS in addition to the prior approval for use in adults with LEMS on November 28, 2018. Fir...

ProAssurance Corporation, headquartered in Birmingham, Alabama, is a property and casualty company that sells professional liability insurance to doctors. The company was founded in 1976 as Mutual Assurance and was later renamed to Medical Assurance in 1997. The name "ProAssurance" was created in 2001 when Medical Assurance merged with Professionals Group. The company is currently the fourth largest medical professional liability insurance writer and has over $6 billion in assets.

CPRX vs PRA — Head-to-Head

Bigger by revenue
PRA
PRA
1.8× larger
PRA
$269.6M
$152.6M
CPRX
Growing faster (revenue YoY)
CPRX
CPRX
+14.7% gap
CPRX
7.6%
-7.1%
PRA
Higher net margin
CPRX
CPRX
22.2% more per $
CPRX
34.5%
12.4%
PRA
Faster 2-yr revenue CAGR
CPRX
CPRX
Annualised
CPRX
24.5%
-2.7%
PRA

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CPRX
CPRX
PRA
PRA
Revenue
$152.6M
$269.6M
Net Profit
$52.7M
$33.4M
Gross Margin
82.9%
Operating Margin
40.5%
17.3%
Net Margin
34.5%
12.4%
Revenue YoY
7.6%
-7.1%
Net Profit YoY
-5.8%
106.4%
EPS (diluted)
$0.40
$0.65

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CPRX
CPRX
PRA
PRA
Q4 25
$152.6M
$269.6M
Q3 25
$148.4M
$279.6M
Q2 25
$146.6M
$276.8M
Q1 25
$141.4M
$272.1M
Q4 24
$141.8M
$290.1M
Q3 24
$128.7M
$285.3M
Q2 24
$122.7M
$290.4M
Q1 24
$98.5M
$284.7M
Net Profit
CPRX
CPRX
PRA
PRA
Q4 25
$52.7M
$33.4M
Q3 25
$52.8M
$1.4M
Q2 25
$52.1M
$21.9M
Q1 25
$56.7M
$-5.8M
Q4 24
$55.9M
$16.2M
Q3 24
$43.9M
$16.4M
Q2 24
$40.8M
$15.5M
Q1 24
$23.3M
$4.6M
Gross Margin
CPRX
CPRX
PRA
PRA
Q4 25
82.9%
Q3 25
84.7%
Q2 25
85.9%
Q1 25
87.3%
Q4 24
84.7%
Q3 24
85.0%
Q2 24
87.4%
Q1 24
87.3%
Operating Margin
CPRX
CPRX
PRA
PRA
Q4 25
40.5%
17.3%
Q3 25
44.7%
1.6%
Q2 25
45.2%
9.9%
Q1 25
44.8%
-2.3%
Q4 24
44.3%
6.5%
Q3 24
39.6%
7.4%
Q2 24
44.2%
6.2%
Q1 24
27.5%
1.9%
Net Margin
CPRX
CPRX
PRA
PRA
Q4 25
34.5%
12.4%
Q3 25
35.6%
0.5%
Q2 25
35.6%
7.9%
Q1 25
40.1%
-2.1%
Q4 24
39.4%
5.6%
Q3 24
34.1%
5.8%
Q2 24
33.2%
5.3%
Q1 24
23.6%
1.6%
EPS (diluted)
CPRX
CPRX
PRA
PRA
Q4 25
$0.40
$0.65
Q3 25
$0.42
$0.03
Q2 25
$0.41
$0.42
Q1 25
$0.45
$-0.11
Q4 24
$0.44
$0.32
Q3 24
$0.35
$0.32
Q2 24
$0.33
$0.30
Q1 24
$0.19
$0.09

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CPRX
CPRX
PRA
PRA
Cash + ST InvestmentsLiquidity on hand
$709.2M
$36.5M
Total DebtLower is stronger
$420.4M
Stockholders' EquityBook value
$954.3M
$1.3B
Total Assets
$1.1B
$5.4B
Debt / EquityLower = less leverage
0.31×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CPRX
CPRX
PRA
PRA
Q4 25
$709.2M
$36.5M
Q3 25
$689.9M
$54.5M
Q2 25
$652.8M
$41.6M
Q1 25
$580.7M
$43.5M
Q4 24
$517.6M
$54.9M
Q3 24
$442.3M
$45.3M
Q2 24
$375.7M
$36.9M
Q1 24
$310.4M
$65.4M
Total Debt
CPRX
CPRX
PRA
PRA
Q4 25
$420.4M
Q3 25
$421.5M
Q2 25
$422.6M
Q1 25
$423.7M
Q4 24
$424.9M
Q3 24
$425.9M
Q2 24
$426.9M
Q1 24
$427.8M
Stockholders' Equity
CPRX
CPRX
PRA
PRA
Q4 25
$954.3M
$1.3B
Q3 25
$920.2M
$1.3B
Q2 25
$856.0M
$1.3B
Q1 25
$794.3M
$1.2B
Q4 24
$727.6M
$1.2B
Q3 24
$660.9M
$1.2B
Q2 24
$608.7M
$1.1B
Q1 24
$561.4M
$1.1B
Total Assets
CPRX
CPRX
PRA
PRA
Q4 25
$1.1B
$5.4B
Q3 25
$1.1B
$5.6B
Q2 25
$971.9M
$5.5B
Q1 25
$908.9M
$5.5B
Q4 24
$851.4M
$5.6B
Q3 24
$772.0M
$5.7B
Q2 24
$706.4M
$5.6B
Q1 24
$646.7M
$5.7B
Debt / Equity
CPRX
CPRX
PRA
PRA
Q4 25
0.31×
Q3 25
0.32×
Q2 25
0.33×
Q1 25
0.34×
Q4 24
0.35×
Q3 24
0.35×
Q2 24
0.38×
Q1 24
0.38×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CPRX
CPRX
PRA
PRA
Operating Cash FlowLast quarter
$44.9M
$-25.6M
Free Cash FlowOCF − Capex
$44.9M
FCF MarginFCF / Revenue
29.4%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
0.85×
-0.77×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CPRX
CPRX
PRA
PRA
Q4 25
$44.9M
$-25.6M
Q3 25
$32.4M
$27.2M
Q2 25
$71.3M
$-28.1M
Q1 25
$60.0M
$-11.6M
Q4 24
$70.9M
$-10.7M
Q3 24
$72.9M
$14.0M
Q2 24
$64.1M
$-12.8M
Q1 24
$31.9M
$-11.6M
Free Cash Flow
CPRX
CPRX
PRA
PRA
Q4 25
$44.9M
Q3 25
Q2 25
$71.3M
Q1 25
Q4 24
$70.8M
Q3 24
$72.6M
Q2 24
$64.1M
Q1 24
$31.7M
FCF Margin
CPRX
CPRX
PRA
PRA
Q4 25
29.4%
Q3 25
Q2 25
48.6%
Q1 25
Q4 24
49.9%
Q3 24
56.4%
Q2 24
52.3%
Q1 24
32.2%
Capex Intensity
CPRX
CPRX
PRA
PRA
Q4 25
0.0%
Q3 25
0.0%
Q2 25
0.0%
Q1 25
0.0%
Q4 24
0.1%
Q3 24
0.2%
Q2 24
0.0%
Q1 24
0.2%
Cash Conversion
CPRX
CPRX
PRA
PRA
Q4 25
0.85×
-0.77×
Q3 25
0.61×
18.81×
Q2 25
1.37×
-1.28×
Q1 25
1.06×
Q4 24
1.27×
-0.66×
Q3 24
1.66×
0.85×
Q2 24
1.57×
-0.83×
Q1 24
1.37×
-2.52×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CPRX
CPRX

Firdapse$97.6M64%
Agamree$35.3M23%
Fycompa$19.6M13%

PRA
PRA

Workers Compensation Insurance Segment$164.4M61%
Other$59.6M22%
Segregated Portfolio Cell Reinsurance$45.7M17%

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