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Side-by-side financial comparison of CRISPR Therapeutics AG (CRSP) and SOUTHERN FIRST BANCSHARES INC (SFST). Click either name above to swap in a different company.
CRISPR Therapeutics AG is the larger business by last-quarter revenue ($35.7M vs $31.8M, roughly 1.1× SOUTHERN FIRST BANCSHARES INC). On growth, SOUTHERN FIRST BANCSHARES INC posted the faster year-over-year revenue change (26.1% vs -82.3%). SOUTHERN FIRST BANCSHARES INC produced more free cash flow last quarter ($29.9M vs $-50.3M).
CRISPR Therapeutics AG is a Swiss–American biotechnology company headquartered in Zug, Switzerland. The company does business as CRISPR Therapeutics, Inc. in the United States. It was one of the first companies formed to utilize the CRISPR gene editing platform to develop medicines for the treatment of various rare and common diseases. The company has approximately 500 employees and has offices in Zug, Switzerland, Boston, Massachusetts, San Francisco, California and London, United Kingdom. I...
First Community Bankshares, Inc. is a $2.43 billion bank holding company and the parent company of First Community Bank of Bluefield, Virginia, in the United States. As of 2012 First Community Bank had 45 locations in Virginia, West Virginia, and North Carolina, and two locations operating as Peoples Community Bank in Tennessee. As of April 21, 2023, First Community had $3.6 billion in assets.
CRSP vs SFST — Head-to-Head
Income Statement — Q4 FY2024 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $35.7M | $31.8M |
| Net Profit | $-37.3M | — |
| Gross Margin | — | — |
| Operating Margin | -181.0% | 40.1% |
| Net Margin | -104.5% | — |
| Revenue YoY | -82.3% | 26.1% |
| Net Profit YoY | -141.8% | — |
| EPS (diluted) | $-0.41 | $1.19 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | — | $31.8M | ||
| Q3 25 | — | $31.1M | ||
| Q2 25 | — | $28.6M | ||
| Q1 25 | — | $26.5M | ||
| Q4 24 | $35.7M | $25.2M | ||
| Q3 24 | — | $23.8M | ||
| Q2 24 | — | $23.1M | ||
| Q1 24 | — | $21.3M |
| Q4 25 | — | — | ||
| Q3 25 | — | $8.7M | ||
| Q2 25 | — | $6.6M | ||
| Q1 25 | — | $5.3M | ||
| Q4 24 | $-37.3M | — | ||
| Q3 24 | — | $4.4M | ||
| Q2 24 | — | $3.0M | ||
| Q1 24 | — | $2.5M |
| Q4 25 | — | 40.1% | ||
| Q3 25 | — | 36.4% | ||
| Q2 25 | — | 30.0% | ||
| Q1 25 | — | 26.1% | ||
| Q4 24 | -181.0% | 27.3% | ||
| Q3 24 | — | 24.1% | ||
| Q2 24 | — | 17.0% | ||
| Q1 24 | — | 15.9% |
| Q4 25 | — | — | ||
| Q3 25 | — | 27.8% | ||
| Q2 25 | — | 23.0% | ||
| Q1 25 | — | 19.9% | ||
| Q4 24 | -104.5% | — | ||
| Q3 24 | — | 18.4% | ||
| Q2 24 | — | 13.0% | ||
| Q1 24 | — | 11.8% |
| Q4 25 | — | $1.19 | ||
| Q3 25 | — | $1.07 | ||
| Q2 25 | — | $0.81 | ||
| Q1 25 | — | $0.65 | ||
| Q4 24 | $-0.41 | $0.69 | ||
| Q3 24 | — | $0.54 | ||
| Q2 24 | — | $0.37 | ||
| Q1 24 | — | $0.31 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $1.9B | — |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $1.9B | $368.7M |
| Total Assets | $2.2B | $4.4B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | $1.9B | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
| Q4 25 | — | $368.7M | ||
| Q3 25 | — | $356.3M | ||
| Q2 25 | — | $345.5M | ||
| Q1 25 | — | $337.6M | ||
| Q4 24 | $1.9B | $330.4M | ||
| Q3 24 | — | $326.5M | ||
| Q2 24 | — | $318.7M | ||
| Q1 24 | — | $315.3M |
| Q4 25 | — | $4.4B | ||
| Q3 25 | — | $4.4B | ||
| Q2 25 | — | $4.3B | ||
| Q1 25 | — | $4.3B | ||
| Q4 24 | $2.2B | $4.1B | ||
| Q3 24 | — | $4.2B | ||
| Q2 24 | — | $4.1B | ||
| Q1 24 | — | $4.1B |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-50.0M | $30.5M |
| Free Cash FlowOCF − Capex | $-50.3M | $29.9M |
| FCF MarginFCF / Revenue | -140.9% | 93.8% |
| Capex IntensityCapex / Revenue | 0.7% | 1.8% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-325.9M | $62.1M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $30.5M | ||
| Q3 25 | — | $14.5M | ||
| Q2 25 | — | $10.5M | ||
| Q1 25 | — | $7.6M | ||
| Q4 24 | $-50.0M | $25.6M | ||
| Q3 24 | — | $26.3M | ||
| Q2 24 | — | $4.0M | ||
| Q1 24 | — | $-2.9M |
| Q4 25 | — | $29.9M | ||
| Q3 25 | — | $14.4M | ||
| Q2 25 | — | $10.4M | ||
| Q1 25 | — | $7.4M | ||
| Q4 24 | $-50.3M | $24.8M | ||
| Q3 24 | — | $26.1M | ||
| Q2 24 | — | $3.9M | ||
| Q1 24 | — | $-3.2M |
| Q4 25 | — | 93.8% | ||
| Q3 25 | — | 46.3% | ||
| Q2 25 | — | 36.3% | ||
| Q1 25 | — | 28.1% | ||
| Q4 24 | -140.9% | 98.2% | ||
| Q3 24 | — | 110.0% | ||
| Q2 24 | — | 16.8% | ||
| Q1 24 | — | -15.0% |
| Q4 25 | — | 1.8% | ||
| Q3 25 | — | 0.3% | ||
| Q2 25 | — | 0.3% | ||
| Q1 25 | — | 0.5% | ||
| Q4 24 | 0.7% | 3.1% | ||
| Q3 24 | — | 0.8% | ||
| Q2 24 | — | 0.4% | ||
| Q1 24 | — | 1.3% |
| Q4 25 | — | — | ||
| Q3 25 | — | 1.67× | ||
| Q2 25 | — | 1.59× | ||
| Q1 25 | — | 1.44× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 6.01× | ||
| Q2 24 | — | 1.32× | ||
| Q1 24 | — | -1.16× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
CRSP
| Collaboration Revenue | $35.0M | 98% |
| Grant | $2.3M | 6% |
SFST
Segment breakdown not available.
