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Side-by-side financial comparison of CASTLE BIOSCIENCES INC (CSTL) and Midland States Bancorp, Inc. (MSBI). Click either name above to swap in a different company.
CASTLE BIOSCIENCES INC is the larger business by last-quarter revenue ($87.0M vs $79.5M, roughly 1.1× Midland States Bancorp, Inc.). Over the past eight quarters, CASTLE BIOSCIENCES INC's revenue compounded faster (9.2% CAGR vs -6.4%).
Castle Biosciences Inc. is a commercial-stage diagnostic firm that develops and markets proprietary, clinically actionable tests for dermatological conditions such as melanoma and other skin cancers, plus rare diseases. It operates mainly in the U.S. healthcare market, focusing on segments with high unmet need for more accurate diagnostics to guide treatment choices.
Rainier Bancorporation was the Seattle-based parent corporation of Rainier National Bank, a Washington state bank with branches throughout the state. Rainier traced its roots back to the National Bank of Commerce, which was founded by Richard Holyoke in 1889. The name Rainier National Bank was adopted in 1974. Rainier Bancorp expanded into Alaska with the purchase of Anchorage's People's Bank & Trust in 1983 and into Oregon with the purchase of Gresham's Mount Hood Security Bank in 1986, expa...
CSTL vs MSBI — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $87.0M | $79.5M |
| Net Profit | — | $18.5M |
| Gross Margin | 79.0% | — |
| Operating Margin | -4.4% | — |
| Net Margin | — | 23.2% |
| Revenue YoY | 0.8% | — |
| Net Profit YoY | — | 739.3% |
| EPS (diluted) | $-0.06 | $0.74 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | — | $79.5M | ||
| Q4 25 | $87.0M | $85.6M | ||
| Q3 25 | $83.0M | $81.1M | ||
| Q2 25 | $86.2M | $82.2M | ||
| Q1 25 | $88.0M | $76.1M | ||
| Q4 24 | $86.3M | $93.9M | ||
| Q3 24 | $85.8M | $92.7M | ||
| Q2 24 | $87.0M | $90.9M |
| Q1 26 | — | $18.5M | ||
| Q4 25 | — | $-2.9M | ||
| Q3 25 | $-501.0K | $7.6M | ||
| Q2 25 | $4.5M | $12.0M | ||
| Q1 25 | $-25.8M | $-141.0M | ||
| Q4 24 | — | $-30.8M | ||
| Q3 24 | $2.3M | $20.4M | ||
| Q2 24 | $8.9M | $25.7M |
| Q1 26 | — | — | ||
| Q4 25 | 79.0% | — | ||
| Q3 25 | 77.5% | — | ||
| Q2 25 | 79.5% | — | ||
| Q1 25 | 81.4% | — | ||
| Q4 24 | 81.3% | — | ||
| Q3 24 | 81.8% | — | ||
| Q2 24 | 83.3% | — |
| Q1 26 | — | — | ||
| Q4 25 | -4.4% | -5.5% | ||
| Q3 25 | -8.2% | 13.9% | ||
| Q2 25 | -4.9% | 18.1% | ||
| Q1 25 | -31.7% | -181.2% | ||
| Q4 24 | 4.7% | -66.5% | ||
| Q3 24 | 5.9% | 26.9% | ||
| Q2 24 | 5.8% | 35.0% |
| Q1 26 | — | 23.2% | ||
| Q4 25 | — | -4.9% | ||
| Q3 25 | -0.6% | 9.3% | ||
| Q2 25 | 5.2% | 14.6% | ||
| Q1 25 | -29.4% | -185.4% | ||
| Q4 24 | — | -52.5% | ||
| Q3 24 | 2.6% | 22.1% | ||
| Q2 24 | 10.3% | 28.3% |
| Q1 26 | — | $0.74 | ||
| Q4 25 | $-0.06 | $-0.22 | ||
| Q3 25 | $-0.02 | $0.24 | ||
| Q2 25 | $0.15 | $0.44 | ||
| Q1 25 | $-0.90 | $-6.58 | ||
| Q4 24 | $0.32 | $-1.49 | ||
| Q3 24 | $0.08 | $0.83 | ||
| Q2 24 | $0.31 | $1.06 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $299.5M | $89.4M |
| Total DebtLower is stronger | $10.1M | $33.2M |
| Stockholders' EquityBook value | $470.9M | $569.5M |
| Total Assets | $578.6M | $6.5B |
| Debt / EquityLower = less leverage | 0.02× | 0.06× |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | $89.4M | ||
| Q4 25 | $299.5M | $127.8M | ||
| Q3 25 | $287.5M | $166.1M | ||
| Q2 25 | $275.9M | $176.6M | ||
| Q1 25 | $275.2M | $102.0M | ||
| Q4 24 | $293.1M | $114.8M | ||
| Q3 24 | $95.0M | $121.9M | ||
| Q2 24 | $85.6M | $124.6M |
| Q1 26 | — | $33.2M | ||
| Q4 25 | $10.1M | — | ||
| Q3 25 | $10.0M | — | ||
| Q2 25 | $10.0M | — | ||
| Q1 25 | $10.0M | — | ||
| Q4 24 | $10.0M | — | ||
| Q3 24 | $10.0M | — | ||
| Q2 24 | $10.0M | — |
| Q1 26 | — | $569.5M | ||
| Q4 25 | $470.9M | $565.5M | ||
| Q3 25 | $467.0M | $584.0M | ||
| Q2 25 | $455.4M | $573.7M | ||
| Q1 25 | $440.3M | $571.4M | ||
| Q4 24 | $455.8M | $710.8M | ||
| Q3 24 | $441.1M | $771.2M | ||
| Q2 24 | $423.9M | $736.8M |
| Q1 26 | — | $6.5B | ||
| Q4 25 | $578.6M | $6.5B | ||
| Q3 25 | $562.8M | $6.9B | ||
| Q2 25 | $544.7M | $7.1B | ||
| Q1 25 | $501.7M | $7.3B | ||
| Q4 24 | $531.2M | $7.5B | ||
| Q3 24 | $514.6M | $7.7B | ||
| Q2 24 | $487.3M | $7.7B |
| Q1 26 | — | 0.06× | ||
| Q4 25 | 0.02× | — | ||
| Q3 25 | 0.02× | — | ||
| Q2 25 | 0.02× | — | ||
| Q1 25 | 0.02× | — | ||
| Q4 24 | 0.02× | — | ||
| Q3 24 | 0.02× | — | ||
| Q2 24 | 0.02× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $26.9M | — |
| Free Cash FlowOCF − Capex | $19.7M | — |
| FCF MarginFCF / Revenue | 22.7% | — |
| Capex IntensityCapex / Revenue | 8.3% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $28.3M | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $26.9M | $125.7M | ||
| Q3 25 | $22.6M | $80.0M | ||
| Q2 25 | $20.8M | $28.1M | ||
| Q1 25 | $-6.0M | $24.7M | ||
| Q4 24 | $24.4M | $176.5M | ||
| Q3 24 | $23.3M | $46.5M | ||
| Q2 24 | $24.0M | $31.4M |
| Q1 26 | — | — | ||
| Q4 25 | $19.7M | $120.3M | ||
| Q3 25 | $7.8M | $78.6M | ||
| Q2 25 | $11.6M | $26.7M | ||
| Q1 25 | $-10.8M | $22.9M | ||
| Q4 24 | $16.8M | $169.6M | ||
| Q3 24 | $17.0M | $44.4M | ||
| Q2 24 | $18.8M | $29.9M |
| Q1 26 | — | — | ||
| Q4 25 | 22.7% | 140.6% | ||
| Q3 25 | 9.4% | 96.9% | ||
| Q2 25 | 13.4% | 32.4% | ||
| Q1 25 | -12.2% | 30.1% | ||
| Q4 24 | 19.5% | 180.6% | ||
| Q3 24 | 19.8% | 47.9% | ||
| Q2 24 | 21.6% | 32.9% |
| Q1 26 | — | — | ||
| Q4 25 | 8.3% | 6.2% | ||
| Q3 25 | 17.9% | 1.7% | ||
| Q2 25 | 10.7% | 1.7% | ||
| Q1 25 | 5.4% | 2.4% | ||
| Q4 24 | 8.8% | 7.3% | ||
| Q3 24 | 7.4% | 2.3% | ||
| Q2 24 | 6.0% | 1.7% |
| Q1 26 | — | — | ||
| Q4 25 | — | — | ||
| Q3 25 | — | 10.58× | ||
| Q2 25 | 4.60× | 2.33× | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | 10.29× | 2.28× | ||
| Q2 24 | 2.69× | 1.22× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
CSTL
| Dermatologic | $48.6M | 56% |
| Non Dermatologic | $38.4M | 44% |
MSBI
| Net Interest Income | $57.4M | 72% |
| Noninterest Income | $22.1M | 28% |
