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Side-by-side financial comparison of CASTLE BIOSCIENCES INC (CSTL) and TRUSTCO BANK CORP N Y (TRST). Click either name above to swap in a different company.

CASTLE BIOSCIENCES INC is the larger business by last-quarter revenue ($87.0M vs $49.5M, roughly 1.8× TRUSTCO BANK CORP N Y). Over the past eight quarters, CASTLE BIOSCIENCES INC's revenue compounded faster (9.2% CAGR vs 6.8%).

Castle Biosciences Inc. is a commercial-stage diagnostic firm that develops and markets proprietary, clinically actionable tests for dermatological conditions such as melanoma and other skin cancers, plus rare diseases. It operates mainly in the U.S. healthcare market, focusing on segments with high unmet need for more accurate diagnostics to guide treatment choices.

TRUSTCO BANK CORP N Y is a regional U.S. financial holding company that provides a full suite of retail and commercial banking products and services, including personal deposit accounts, mortgage loans, small business financing, and wealth management solutions. It primarily operates across New York, Florida, and several other U.S. states, serving individual consumers and small business client segments.

CSTL vs TRST — Head-to-Head

Bigger by revenue
CSTL
CSTL
1.8× larger
CSTL
$87.0M
$49.5M
TRST
Faster 2-yr revenue CAGR
CSTL
CSTL
Annualised
CSTL
9.2%
6.8%
TRST

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
CSTL
CSTL
TRST
TRST
Revenue
$87.0M
$49.5M
Net Profit
$16.3M
Gross Margin
79.0%
Operating Margin
-4.4%
Net Margin
32.9%
Revenue YoY
0.8%
Net Profit YoY
14.1%
EPS (diluted)
$-0.06

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CSTL
CSTL
TRST
TRST
Q1 26
$49.5M
Q4 25
$87.0M
$48.2M
Q3 25
$83.0M
$47.8M
Q2 25
$86.2M
$46.6M
Q1 25
$88.0M
$45.3M
Q4 24
$86.3M
$43.3M
Q3 24
$85.8M
$43.6M
Q2 24
$87.0M
$43.4M
Net Profit
CSTL
CSTL
TRST
TRST
Q1 26
$16.3M
Q4 25
$15.6M
Q3 25
$-501.0K
$16.3M
Q2 25
$4.5M
$15.0M
Q1 25
$-25.8M
$14.3M
Q4 24
$11.3M
Q3 24
$2.3M
$12.9M
Q2 24
$8.9M
$12.6M
Gross Margin
CSTL
CSTL
TRST
TRST
Q1 26
Q4 25
79.0%
Q3 25
77.5%
Q2 25
79.5%
Q1 25
81.4%
Q4 24
81.3%
Q3 24
81.8%
Q2 24
83.3%
Operating Margin
CSTL
CSTL
TRST
TRST
Q1 26
Q4 25
-4.4%
43.7%
Q3 25
-8.2%
44.6%
Q2 25
-4.9%
42.3%
Q1 25
-31.7%
41.3%
Q4 24
4.7%
34.0%
Q3 24
5.9%
38.8%
Q2 24
5.8%
37.9%
Net Margin
CSTL
CSTL
TRST
TRST
Q1 26
32.9%
Q4 25
32.3%
Q3 25
-0.6%
34.0%
Q2 25
5.2%
32.3%
Q1 25
-29.4%
31.5%
Q4 24
26.0%
Q3 24
2.6%
29.5%
Q2 24
10.3%
28.9%
EPS (diluted)
CSTL
CSTL
TRST
TRST
Q1 26
Q4 25
$-0.06
$0.85
Q3 25
$-0.02
$0.86
Q2 25
$0.15
$0.79
Q1 25
$-0.90
$0.75
Q4 24
$0.32
$0.59
Q3 24
$0.08
$0.68
Q2 24
$0.31
$0.66

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CSTL
CSTL
TRST
TRST
Cash + ST InvestmentsLiquidity on hand
$299.5M
Total DebtLower is stronger
$10.1M
$112.9M
Stockholders' EquityBook value
$470.9M
$670.9M
Total Assets
$578.6M
$6.5B
Debt / EquityLower = less leverage
0.02×
0.17×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CSTL
CSTL
TRST
TRST
Q1 26
Q4 25
$299.5M
$730.4M
Q3 25
$287.5M
$695.6M
Q2 25
$275.9M
$713.6M
Q1 25
$275.2M
$756.1M
Q4 24
$293.1M
$641.8M
Q3 24
$95.0M
$523.0M
Q2 24
$85.6M
$536.1M
Total Debt
CSTL
CSTL
TRST
TRST
Q1 26
$112.9M
Q4 25
$10.1M
Q3 25
$10.0M
Q2 25
$10.0M
Q1 25
$10.0M
Q4 24
$10.0M
Q3 24
$10.0M
Q2 24
$10.0M
Stockholders' Equity
CSTL
CSTL
TRST
TRST
Q1 26
$670.9M
Q4 25
$470.9M
$686.6M
Q3 25
$467.0M
$692.0M
Q2 25
$455.4M
$692.8M
Q1 25
$440.3M
$687.8M
Q4 24
$455.8M
$676.3M
Q3 24
$441.1M
$669.0M
Q2 24
$423.9M
$655.2M
Total Assets
CSTL
CSTL
TRST
TRST
Q1 26
$6.5B
Q4 25
$578.6M
$6.4B
Q3 25
$562.8M
$6.3B
Q2 25
$544.7M
$6.3B
Q1 25
$501.7M
$6.3B
Q4 24
$531.2M
$6.2B
Q3 24
$514.6M
$6.1B
Q2 24
$487.3M
$6.1B
Debt / Equity
CSTL
CSTL
TRST
TRST
Q1 26
0.17×
Q4 25
0.02×
Q3 25
0.02×
Q2 25
0.02×
Q1 25
0.02×
Q4 24
0.02×
Q3 24
0.02×
Q2 24
0.02×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CSTL
CSTL
TRST
TRST
Operating Cash FlowLast quarter
$26.9M
Free Cash FlowOCF − Capex
$19.7M
FCF MarginFCF / Revenue
22.7%
Capex IntensityCapex / Revenue
8.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$28.3M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CSTL
CSTL
TRST
TRST
Q1 26
Q4 25
$26.9M
$57.6M
Q3 25
$22.6M
$12.8M
Q2 25
$20.8M
$27.1M
Q1 25
$-6.0M
$1.3M
Q4 24
$24.4M
$59.4M
Q3 24
$23.3M
$16.5M
Q2 24
$24.0M
$18.7M
Free Cash Flow
CSTL
CSTL
TRST
TRST
Q1 26
Q4 25
$19.7M
$45.7M
Q3 25
$7.8M
$10.0M
Q2 25
$11.6M
$24.9M
Q1 25
$-10.8M
$-3.3M
Q4 24
$16.8M
$54.6M
Q3 24
$17.0M
$15.6M
Q2 24
$18.8M
$17.6M
FCF Margin
CSTL
CSTL
TRST
TRST
Q1 26
Q4 25
22.7%
95.0%
Q3 25
9.4%
20.9%
Q2 25
13.4%
53.5%
Q1 25
-12.2%
-7.2%
Q4 24
19.5%
126.0%
Q3 24
19.8%
35.7%
Q2 24
21.6%
40.5%
Capex Intensity
CSTL
CSTL
TRST
TRST
Q1 26
Q4 25
8.3%
24.6%
Q3 25
17.9%
5.9%
Q2 25
10.7%
4.5%
Q1 25
5.4%
10.0%
Q4 24
8.8%
11.3%
Q3 24
7.4%
2.1%
Q2 24
6.0%
2.6%
Cash Conversion
CSTL
CSTL
TRST
TRST
Q1 26
Q4 25
3.70×
Q3 25
0.79×
Q2 25
4.60×
1.80×
Q1 25
0.09×
Q4 24
5.27×
Q3 24
10.29×
1.28×
Q2 24
2.69×
1.49×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CSTL
CSTL

Dermatologic$48.6M56%
Non Dermatologic$38.4M44%

TRST
TRST

Net Interest Income$44.7M90%
Noninterest Income$4.8M10%

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