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Side-by-side financial comparison of CytomX Therapeutics, Inc. (CTMX) and ISABELLA BANK CORP (ISBA). Click either name above to swap in a different company.

ISABELLA BANK CORP is the larger business by last-quarter revenue ($21.2M vs $18.7M, roughly 1.1× CytomX Therapeutics, Inc.). ISABELLA BANK CORP runs the higher net margin — 22.2% vs -0.8%, a 23.0% gap on every dollar of revenue. On growth, ISABELLA BANK CORP posted the faster year-over-year revenue change (14.3% vs -25.7%). ISABELLA BANK CORP produced more free cash flow last quarter ($23.3M vs $-15.8M). Over the past eight quarters, ISABELLA BANK CORP's revenue compounded faster (12.6% CAGR vs -15.9%).

CytomX Therapeutics is a clinical-stage biotechnology company specializing in innovative cancer immunotherapies. It leverages its proprietary Probody technology platform to develop targeted therapies that activate exclusively in tumor microenvironments, minimizing off-target toxicities, with a pipeline covering multiple solid tumor indications and partnerships with leading global pharmaceutical firms.

The Bank of the Philippine Islands is a universal bank in the Philippines. It is the oldest bank in both the Philippines and Southeast Asia. It is the fourth largest bank in terms of assets, the second largest bank in terms of market capitalization, and one of the most profitable banks in the Philippines.

CTMX vs ISBA — Head-to-Head

Bigger by revenue
ISBA
ISBA
1.1× larger
ISBA
$21.2M
$18.7M
CTMX
Growing faster (revenue YoY)
ISBA
ISBA
+40.0% gap
ISBA
14.3%
-25.7%
CTMX
Higher net margin
ISBA
ISBA
23.0% more per $
ISBA
22.2%
-0.8%
CTMX
More free cash flow
ISBA
ISBA
$39.1M more FCF
ISBA
$23.3M
$-15.8M
CTMX
Faster 2-yr revenue CAGR
ISBA
ISBA
Annualised
ISBA
12.6%
-15.9%
CTMX

Income Statement — Q2 FY2025 vs Q4 FY2025

Metric
CTMX
CTMX
ISBA
ISBA
Revenue
$18.7M
$21.2M
Net Profit
$-154.0K
$4.7M
Gross Margin
Operating Margin
-6.9%
32.2%
Net Margin
-0.8%
22.2%
Revenue YoY
-25.7%
14.3%
Net Profit YoY
97.6%
17.4%
EPS (diluted)
$0.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CTMX
CTMX
ISBA
ISBA
Q4 25
$21.2M
Q3 25
$20.5M
Q2 25
$18.7M
$18.8M
Q1 25
$50.9M
$18.1M
Q4 24
$38.1M
$18.5M
Q3 24
$33.4M
$18.0M
Q2 24
$25.1M
$17.2M
Q1 24
$41.5M
$16.7M
Net Profit
CTMX
CTMX
ISBA
ISBA
Q4 25
$4.7M
Q3 25
$5.2M
Q2 25
$-154.0K
$5.0M
Q1 25
$23.5M
$3.9M
Q4 24
$18.9M
$4.0M
Q3 24
$5.7M
$3.3M
Q2 24
$-6.5M
$3.5M
Q1 24
$13.8M
$3.1M
Operating Margin
CTMX
CTMX
ISBA
ISBA
Q4 25
32.2%
Q3 25
30.7%
Q2 25
-6.9%
32.8%
Q1 25
44.4%
26.9%
Q4 24
46.4%
26.0%
Q3 24
12.3%
21.3%
Q2 24
-33.7%
23.9%
Q1 24
28.1%
21.8%
Net Margin
CTMX
CTMX
ISBA
ISBA
Q4 25
22.2%
Q3 25
25.6%
Q2 25
-0.8%
26.7%
Q1 25
46.2%
21.9%
Q4 24
49.6%
21.6%
Q3 24
17.2%
18.2%
Q2 24
-26.0%
20.3%
Q1 24
33.3%
18.7%
EPS (diluted)
CTMX
CTMX
ISBA
ISBA
Q4 25
$0.64
Q3 25
$0.71
Q2 25
$0.68
Q1 25
$0.53
Q4 24
$0.54
Q3 24
$0.44
Q2 24
$0.46
Q1 24
$0.42

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CTMX
CTMX
ISBA
ISBA
Cash + ST InvestmentsLiquidity on hand
$49.0M
$26.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$119.9M
$231.4M
Total Assets
$175.1M
$2.2B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CTMX
CTMX
ISBA
ISBA
Q4 25
$26.0M
Q3 25
$161.3M
Q2 25
$49.0M
$108.6M
Q1 25
$47.6M
$69.2M
Q4 24
$38.1M
$24.5M
Q3 24
$40.6M
$27.4M
Q2 24
$43.2M
$23.6M
Q1 24
$36.2M
$25.2M
Stockholders' Equity
CTMX
CTMX
ISBA
ISBA
Q4 25
$231.4M
Q3 25
$227.4M
Q2 25
$119.9M
$220.5M
Q1 25
$25.0M
$215.6M
Q4 24
$-456.0K
$210.3M
Q3 24
$-23.5M
$213.0M
Q2 24
$-31.2M
$202.2M
Q1 24
$-31.7M
$200.7M
Total Assets
CTMX
CTMX
ISBA
ISBA
Q4 25
$2.2B
Q3 25
$2.3B
Q2 25
$175.1M
$2.2B
Q1 25
$98.5M
$2.1B
Q4 24
$120.5M
$2.1B
Q3 24
$139.0M
$2.1B
Q2 24
$159.2M
$2.1B
Q1 24
$184.7M
$2.1B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CTMX
CTMX
ISBA
ISBA
Operating Cash FlowLast quarter
$-15.8M
$26.8M
Free Cash FlowOCF − Capex
$-15.8M
$23.3M
FCF MarginFCF / Revenue
-84.6%
110.2%
Capex IntensityCapex / Revenue
0.1%
16.4%
Cash ConversionOCF / Net Profit
5.72×
TTM Free Cash FlowTrailing 4 quarters
$-77.7M
$36.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CTMX
CTMX
ISBA
ISBA
Q4 25
$26.8M
Q3 25
$2.7M
Q2 25
$-15.8M
$7.8M
Q1 25
$-21.0M
$4.7M
Q4 24
$-19.9M
$19.6M
Q3 24
$-20.7M
$3.6M
Q2 24
$-19.5M
$5.5M
Q1 24
$-26.0M
$3.4M
Free Cash Flow
CTMX
CTMX
ISBA
ISBA
Q4 25
$23.3M
Q3 25
$1.7M
Q2 25
$-15.8M
$7.2M
Q1 25
$-21.2M
$3.7M
Q4 24
$-20.0M
$17.5M
Q3 24
$-20.7M
$3.2M
Q2 24
$-19.6M
$5.1M
Q1 24
$-26.2M
$2.6M
FCF Margin
CTMX
CTMX
ISBA
ISBA
Q4 25
110.2%
Q3 25
8.5%
Q2 25
-84.6%
38.5%
Q1 25
-41.6%
20.6%
Q4 24
-52.5%
94.6%
Q3 24
-62.1%
17.7%
Q2 24
-78.2%
29.8%
Q1 24
-63.1%
15.7%
Capex Intensity
CTMX
CTMX
ISBA
ISBA
Q4 25
16.4%
Q3 25
5.0%
Q2 25
0.1%
3.2%
Q1 25
0.2%
5.5%
Q4 24
0.2%
11.4%
Q3 24
0.1%
2.0%
Q2 24
0.4%
2.4%
Q1 24
0.3%
4.9%
Cash Conversion
CTMX
CTMX
ISBA
ISBA
Q4 25
5.72×
Q3 25
0.52×
Q2 25
1.56×
Q1 25
-0.89×
1.19×
Q4 24
-1.05×
4.91×
Q3 24
-3.61×
1.08×
Q2 24
1.59×
Q1 24
-1.89×
1.10×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CTMX
CTMX

Bristol Myers Squibb Company$11.6M62%
Astellas Pharma Inc$4.6M25%
Regeneron Pharmaceuticals Inc$2.1M11%

ISBA
ISBA

Segment breakdown not available.

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